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Glutathione CAS:70-18-8

Name: Glutathione CAS:70-18-8
Brand: Orient
SKU: pr2512121414
Price: 4 USD
Availability: InStock

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CAS No.:

70-18-8

Grade:

Industrial Grade

Content:

98%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 25KG, 200KG, 1000KG, customized

Price valid (until):

2026-01-12

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Focusing on innovative research, development, and production in the field of fine chemicals, we prioritize technology, quality, and market orientation. We collaborate with global partners to build a high-tech chemical industry chain and promote sustainable development in the industry.

The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

Glutathione Basic information

Features and functions Three active peptide compound The physical and chemical properties Food additives Foods rich in glutathione Reduced glutathione Antidote Antiallergic agent Protect liver agent GSH depletion Antioxidants The preparation of GSH Uses

Product Name:	Glutathione
Synonyms:	glutatiol;glutatione;glutide;glutinal;isethion;l-glutatione;N(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine;n-(n-l-gamma-glutamyl-l-cysteinyl)-glycin
CAS:	70-18-8
MF:	C10H17N3O6S
MW:	307.32
EINECS:	200-725-4
Product Categories:	chemical;Inhibitors;Amino Acids & Derivatives;Material;Pharmaceutical intermediates;pharmaceutical;pharmacetical;Amino Acids 13C, 2H, 15N;Antioxidant;Biochemistry;Intermediates & Fine Chemicals;Pharmaceuticals;API;70-18-8
Mol File:	70-18-8.mol

Glutathione Chemical Properties

Melting point	192-195 °C (dec.) (lit.)
alpha	-16.5 º (c=2, H2O)
Boiling point	754.5±60.0 °C(Predicted)
bulk density	160kg/m3
density	1.4482 (rough estimate)
refractive index	-17 ° (C=2, H2O)
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL
pka	pK1 2.12; pK2 3.53; pK3 8.66; pK4 9.12(at 25℃)
form	powder
color	White
PH	3 (10g/l, H2O, 20°C)
Odor	Odorless
Optical Rotation	-21.327 (H2O)
Water Solubility	soluble
Merck	14,4475
BRN	1729812
Sequence	H-γ-Glu-Cys-Gly-OH
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	RWSXRVCMGQZWBV-WDSKDSINSA-N
LogP	-1.645 (est)
CAS DataBase Reference	70-18-8(CAS DataBase Reference)
EPA Substance Registry System	Glutathione (70-18-8)

Safety Information

Hazard Codes	Xi
Risk Statements	68-36/37/38
Safety Statements	24/25-36/37/39-27-26
WGK Germany	2
RTECS	MC0556000
F	9-23
TSCA	Yes
HS Code	29309070

MSDS Information

Glutathione Usage And Synthesis

Features and functions	Glutathione is composed of glutamic acid, cysteine and glycine by peptide bonds condensation of three peptide compounds,which is the most important antioxidant stress of low molecular mercaptan in mammalian cells.We discovered it in 1921 and determined the chemical structure in 1930 , the famous American nutrition health experts said Dr Al sensitive del glutathione is three times the efficiency of the anti-aging amino acid, also known as the antioxidant master of nature, the appearance is colorless transparent thin granular crystal, it is soluble in water, dilute alcohol, liquid ammonia, dimethyl formamide,and it’s insoluble in ethanol, ether, acetone.Its solid character is stable, its aqueous solution is easy oxidized in the air for oxidized glutathione, widely exists in baker's yeast, wheat germ, animal liver, chicken blood, pig blood, tomato, pineapple, cucumber, of which is highest in the wheat germ and liver, content as high as 100~1000 mg/100 g.With antioxidant, scavenging free radicals, detoxification, enhance immunity, anti-aging, anti-cancer, anti radiation damage, and other functions.It also helps white blood cells to kill bacteria and prevent the oxidation of the vitamins C and E, to prevent stroke and cataract formation.In addition, glutathione can bind the carcinogen, than excrete them through the urine in vitro. The liver is the most important detoxification organs, which contains rich in glutathione (GSH) on the liver function such as synthesis, detoxification, estrogen inactivated protection.It is the first anti-oxidant that the human body is to counteract the damage of free radicals, and the free radical is a contributing factor to the aging and disease.When the liver is damage, such as suffering from all kinds of liver disease, the body will consume large amounts of GSH to help repair the injured liver and detoxification, that cause the body's glutathione are greatly reduced.But this time we need to take some glutathione peptide drugs, is advantageous to the injury of liver to repair itself.Thus, glutathione peptide drugs are suitable for viral hepatitis (hepatitis a and hepatitis b, etc.), alcoholic liver disease,drug-induced liver disease, fatty liver disease ,it’s a good medicine to protect liver.
Three active peptide compound	Glutathione (Glutathione, GSH) is made up of glutamic acid, cysteine and glycine by peptide bonds condensation of three peptide compounds, chemical name called gamma-L-glutamine-L-in ammonia acyl-glycine, its structural formula is shown in figure 1. Structured from the figure, the GSH and other peptide and protein is different, it's a special peptide bond in the molecule,by glutamate gamma carboxyl (-COOH) and alpha amino-cysteine (NH2) peptidebond condensation. Figure 1 :Glutathione (GSH) chemical structural formula GSH biosynthesis is directly controlled by its synthetase, rather than as protein synthesis is conducted on the ribosome, glutathione biosynthesis includes the following two reaction, as shown in figure 2. Figure 2: The synthesis of GSH Hopkins first discovered glutathione as early as 1921 , than divided it into reduced glutathione (GSH) and oxidative type (GSSG) two kinds.GSH exists in all living cells, it’s higher in yeast, wheat germ and liver, 100~1000 mg/100 g.According to recent data, S.c erevisiae Jacqueline Nottingham-5-8 strains of GSH content of up to 3058 mg/3058 g.In dry yeast type oxidation GSH exists, and almost all people in red blood cells were reduced glutathione, GSH can be synthesized in the red blood cells.Glutathione molecule contains a lively mercapto-SH, susceptible to oxidative dehydrogenation, two molecules of reduced glutathione (GSH) into a molecular dehydrogenation oxidation type glutathione (GSSG).Peptide by oxidation type in two three disulfide bond together, which play an important physiological role in living organisms is reduced glutathione, GSSG as GSH is physiological activity.
The physical and chemical properties	Glutathione molecular weight of 307.33, melting point of 189~193 ℃ (decomposition), crystal is colorless transparent thin cylindrical in shape and isoelectric point of 5.93.It is soluble in water, dilute alcohol, liquid ammonia and methyl formamide, and insoluble in alcohol, ether and acetone.Organisms only with physiological activity, GSH and GSSG need to restore to play its important physiological functions.The GSH under high water activity is not easy to save, only controlling the water activity below 0.3 to long-term stability.Studies have found that in vitamin C (pH3.3) in aqueous solution containing GSH, with strong reducing effect of vitamin C, GSH no oxidation of solution for the GSSG, but the decomposition speed is accelerated;But in the vitamin C solution GSSG will not change as GSH, and save the stability is very good.And oral intake of GSSG in the upper small intestine can be restored as GSH, in the small intestine epithelial cell surface by gamma GTP (GSH is decomposed into glutamic acid and Cys-Gly) and the role of the dipeptide enzyme and is absorbed, can also play an important physiological function. Glutathione is widely found in animals and plants, and the contents of the bread yeast, wheat germ and animal liver are very high,100~100 mg/1000 g;Content is also rich in human and animal blood, such as human blood contains 26~34 mg/100 g, chicken blood contains 58-73 mg/73 g, pig blood contains 10~15 mg/100 g, the dog blood contains 14~22 mg/100 g.Many vegetables, potato and corn also contains GSH (see table 1).

First aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Firefighting measures

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

ECHEMI Editorial Reference

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.
Solid
Glutathione is a tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine. It has a role as a skin lightening agent, a human metabolite, an Escherichia coli metabolite, a mouse metabolite, an antioxidant and a cofactor. It is a tripeptide, a thiol and a L-cysteine derivative. It is a conjugate acid of a glutathionate(1-).|A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.|Glutathione is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue. Glutathione acts as an antioxidant, a free radical scavenger and a detoxifying agent. Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids, and in the synthesis of leukotrienes. As a substrate for glutathione S-transferase, this agent reacts with a number of harmful chemical species, such as halides, epoxides and free radicals, to form harmless inactive products. In erythrocytes, these reactions prevent oxidative damage through the reduction of methemoglobin and peroxides. Glutathione is also involved in the formation and maintenance of disulfide bonds in proteins and in the transport of amino acids across cell membranes.

Certificates

Basic Info

Product Name:

Glutathione

Other Name:

Glycine,L-γ-glutamyl-L-cysteinyl-;Glutathione;Glycine,N-(N-L-γ-glutamyl-L-cysteinyl)-;L-γ-Glutamyl-L-cysteinylglycine;γ-L-Glutamyl-L-cysteinylglycine;Glutathione-SH;GSH;L-Glutathione;Reduced glutathione;Triptide;Glutide;Tathion;Tathione;Copren;Deltathione;Glutathion;Glutinal;Isethion;Neuthion;Agifutol S;γ-Glutamylcysteinylglycine;N-(N-L-γ-Glutamyl-L-cysteinyl)glycine;Bakezyme RX;ReadiSorb;Atomolan;High Thione Extract YH 15;N5-((R)-1-((Carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)-L-glutamine;TAD 600;1109226-07-4;1655518-50-5

CAS No.:

70-18-8

Molecular Formula:

C10H17N3O6S

InChIKeys:

InChIKey=RWSXRVCMGQZWBV-WDSKDSINSA-N

Molecular Weight:

307.32300

Exact Mass:

307.32

EC Number:

200-725-4

UNII:

GAN16C9B8O

NSC Number:

758199

DSSTox ID:

DTXSID6023101

NCI Thesaurus Code:

C523

ATC Code:

V - Various

HScode:

2930909090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

197.62000

XLogP3:

-4.5

Appearance:

Solid

Density:

1.441 g/cm3

Melting Point:

195 °C

Boiling Point:

410.1ºC

Flash Point:

410.1±32.9 °C

Refractive Index:

1.571

Water Solubility:

H2O: 292.5 mg/mL

Storage Conditions:

2-8ºC

Collision Cross Section:

167.4 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|168.23 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|164.24 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|165 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|167.8 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|167 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|162.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|164.8 Å² [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|165.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|164.8 Å² [M-2H+Na]-

See More Glutathione Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Glutathione Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

72 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Glutathione Quality Research Chemical Peptide Cas Number 70-18-8 Lyophilized Powder	50 PCS	Apr 14, 2026
Colombia	Glutathione \| Peptides \| 99% Purity \| CAS 70-18-8 \| White Powder \| Antioxidant Detox	5 G	May 12, 2026
India	Glutathione	100.00 G	Nov 22, 2024
Philippines	Glutathione	50 MG	Aug 19, 2026
United States	Glutathione	1 MG	Aug 10, 2026
United States	Glutathion	100 MG	Aug 3, 2026
United Kingdom	Glutathione	10 MT	Jul 30, 2026
United States	Glutathione	100 MG	Jul 27, 2026
United Kingdom	Glutathione 1200mg	50	Jul 23, 2026
Canada	Glutathione	10 G	Jul 16, 2026
United States	Glutathione	500 PCS	Jun 6, 2026
South Africa	Glutathione	50 MG	Jun 1, 2026
United States	Glutathione	10 MT	May 29, 2026
United Kingdom	Glutathione	100 G	May 16, 2026
United States	Glutathione	1500 MG	May 8, 2026
United States	Glutathione	1000 MG	Apr 3, 2026
United States	Glutathione 1500	100 MT	Mar 26, 2026
United States	Glutathione	1500 BOU	Mar 16, 2026
United States	Glutathione	1 KG	Feb 18, 2026
Australia	GLucathione	3 PCS	Feb 12, 2026

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Glutathione CAS:70-18-8

Product Description

Seller Information

Inquiry History

First aid measures

Firefighting measures

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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