 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > (-)-Caryophyllene for Sale > β-Caryophyllene CAS:87-44-5

β-Caryophyllene CAS:87-44-5 buy - large image1

β-Caryophyllene CAS:87-44-5 buy - image1

β-Caryophyllene CAS:87-44-5 buy - image2

β-Caryophyllene CAS:87-44-5 buy - image3

β-Caryophyllene CAS:87-44-5 buy - image4

β-Caryophyllene CAS:87-44-5

Name: β-Caryophyllene CAS:87-44-5
Brand: Orient
SKU: pr2512192389
Price: 4 USD
Availability: InStock

TDS 9 Inquiries

Unit Price: Get Latest Price 

CAS No.:

87-44-5

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2026-01-19

Contact Supplier

 Chat Now

Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Name:	β-Caryophyllene
Synonyms:	β-caryophyllen;1-caryophyllene;2-Methylene-6,10,10-trimethyl bicyclo[7.2.0]undec-5-ene;BetaCarryophellene;β-caryophyllene,[1R-(1R,4E,9S)]-4,11,11-trimethyl-8-methylene-bicyclo[7.2.0]undec-4-ene,(E)-caryophyllene;Bicyclo7.2.0undec-4-ene, 4,11,11-trimethyl-8-methylene-, (1R,4E,9S)-;CARYOPHYLLENE, (-)-trans-(SG);HUMULENE, alpha-(SG)
CAS:	87-44-5
MF:	C15H24
MW:	204.35
EINECS:	201-746-1
Product Categories:	Chiral Reagents;Intermediates & Fine Chemicals;Sesqui-Terpenoids;Biochemistry;Terpenes;Pharmaceuticals;Terpenes (Others)
Mol File:	87-44-5.mol

β-Caryophyllene Chemical Properties

Melting point	<25℃
alpha	D -8 to -9° (chloroform)
Boiling point	129-130 °C/14 mmHg (lit.)
density	0.901 g/mL at 25 °C (lit.)
vapor pressure	6Pa at 20℃
refractive index	n20/D 1.5(lit.)
FEMA	2252 \| BETA-CARYOPHYLLENE
Fp	205 °F
storage temp.	-20°C
solubility	Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
form	Liquid
color	Colourless
Specific Gravity	0.90
Odor	at 100.00 %. sweet woody spice clove dry
Odor Type	spicy
Optical Rotation	[α]23/D 7.5°, neat
biological source	synthetic
Water Solubility	88μg/L at 20℃
Merck	14,1875
JECFA Number	1324
BRN	2044564
Stability:	Light Sensitive
Cosmetics Ingredients Functions	PERFUMING SKIN CONDITIONING FRAGRANCE
LogP	6.23 at 25℃
CAS DataBase Reference	87-44-5(CAS DataBase Reference)
EPA Substance Registry System	Bicyclo[7.2.0]undec-4-ene, 4,11,11-trimethyl-8-methylene-, (1R,4E,9S)- (87-44-5)

Safety Information

Risk Statements	36/37/38
Safety Statements	26-36-24/25
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
RTECS	DT8400000
HS Code	29021990

MSDS Information

β-Caryophyllene Usage And Synthesis

Description	β-Caryophyllene is a sesquiterpene that has been found in plants, including C. sativa, C. indica, and hemp, and has diverse biological activities, including lipid metabolic, antioxidant, anti-neuroinflammatory, anti-proliferative, and antinociceptive properties.
Chemical Properties	β-Caryophyllene has a woody-spicy, dry, clove-like aroma.
Occurrence	Three isomers (α-, β-, and γ-caryophyllene) are found in nature. The β-isomer is the most frequently encountered and most abundant. This sesquiterpene hydrocarbon occurs naturally in approximately 60 essential oils, mainly in that of cloves, from which it was originally isolated. The chemical structure has been thoroughly studied; other studies have been conducted on the isolation and the dipolar moment, as well as on its oxide. Reported found in lime peel oil, lemon, grapefruit, guava fruit, raspberry, black currant, carrot, celery seed, cinnamon bark, anise, nutmeg, cumin seed, ginger, pepper, peppermint oil, mace, laurel and caraway herb.
Uses	β-Caryophyllene is notable for having a cyclobutane ring, a rarity in nature. β-Caryophyllene is one of the chemical compounds that contributes to the spiciness of black pepper. β-Caryophyllene was shown to selectively bind to the cannabinoid receptor type-2 (CB2) and to exert significant cannabimimetic antiinflammatory effects in mice.
Definition	ChEBI: A beta-caryophyllene in which the stereocentre adjacent to the exocyclic double bond has S configuration while the remaining stereocentre has R configuration. It is the most commonly occurring form of
Preparation	Isolated from oil of clove stems and separated from eugenol by treating the oil with 7% sodium carbonate solution, extracting with ether, repeating the carbonate treatment on the concentrated extracts, and finally steam distilling.
Aroma threshold values	Detection at 64 to 90 ppb
Taste threshold values	Taste characteristics at 50 ppm: spicy, pepper-like, woody, camphoraceous with a citrus background.
Synthesis Reference(s)	Journal of the American Chemical Society, 86, p. 485, 1964 DOI: 10.1021/ja01057a040
Air & Water Reactions	Insoluble in water.
Reactivity Profile	The unsaturated aliphatic hydrocarbons, such as BETA-CARYOPHYLLENE, are generally much more reactive than the alkanes. Strong oxidizers may react vigorously with them. Reducing agents can react exothermically to release gaseous hydrogen. In the presence of various catalysts (such as acids) or initiators, compounds in this class can undergo very exothermic addition polymerization reactions.
Health effects	β-caryophyllene has shown anti-inflammatory activity via decreasing TLR-4, IL-1?, and TNF-α levels. It attenuated oxidative stress by restoring antioxidant enzymes and repressing lipid peroxidation as well as GSH depletion.
Fire Hazard	BETA-CARYOPHYLLENE is combustible.
Safety Profile	A skin irritant. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
Carcinogenicity	Caryophyllene showed significant activity as an inducer of the detoxifying enzyme glutathione S-transferase in the mouse liver and small intestine. The ability of natural anticarcinogens to induce detoxifying enzymes has been found to correlate with their activity in the inhibition of chemical carcinogenesis (253a).

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

Shop Orthophosphorus acid 10294-56-1-Detailed Image 1

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 2

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 3

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 4

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 5

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 6

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 7

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 8

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 9

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 10

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 11

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 12

—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

(-)-Caryophyllene

Other Name:

Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-,(1R,4E,9S)-;Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-,(E)-(1R,9S)-(-)-;Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-,[1R-(1R*,4E,9S*)]-;(1R,4E,9S)-4,11,11-Trimethyl-8-methylenebicyclo[7.2.0]undec-4-ene;trans-Caryophyllene;Caryophyllene;l-Caryophyllene;β-Caryophyllene;β-Caryophyllen;(-)-β-Caryophyllene;β-Caryophyllene,(-);(-)-Caryophyllene;(-)-trans-Caryophyllene;(-)-E-Caryophyllene;(E)-Caryophyllene;(-)-(E)-Caryophyllene;NSC 11906;Caryophyllene B;trans-β-Caryophyllene;Caryophylline;1407-53-0;8007-38-3;1233519-47-5

CAS No.:

87-44-5

Molecular Formula:

C15H24

InChIKeys:

InChIKey=NPNUFJAVOOONJE-FLFDDASRSA-N

Molecular Weight:

204.35

Exact Mass:

204.35

EC Number:

201-746-1

DSSTox ID:

DTXSID8024739

HScode:

2902199090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

0 Å²

XLogP3:

4.72520

Appearance:

Beta-caryophyllene is a pale yellow oily liquid with an odor midway between odor of cloves and turpentine. (NTP, 1992)

Density:

0.9052 g/cm³ @ Temp: 17 °C

Melting Point:

<25 °C

Boiling Point:

129.5 °C

Flash Point:

205 °F

Refractive Index:

1.495

Water Solubility:

less than 1 mg/mL at 70° F (NTP, 1992)

Storage Conditions:

2-8°C

Toxicity:

Celiac-rat LD:> 48 mg/kg

Flammability characteristics:

In case of high temperature, open flame, strong oxidant is flammable; thermal decomposition is spicy and stimulates smoke

Specific rotation:

D -8 to -9° (chloroform)

OH:

2.00e-10 cm3/molecule*sec

Air and Water Reactions:

Insoluble in water.

Reactive Group:

Hydrocarbons, Aliphatic Unsaturated

Reactivity Profile:

The unsaturated aliphatic hydrocarbons, such as BETA-CARYOPHYLLENE, are generally much more reactive than the alkanes. Strong oxidizers may react vigorously with them. Reducing agents can react exothermically to release gaseous hydrogen. In the presence of various catalysts (such as acids) or initiators, compounds in this class can undergo very exothermic addition polymerization reactions.

See More (-)-Caryophyllene Properties 

Hazard Identification

Classification of the substance or mixture

Aspiration hazard, Category 1

Skin sensitization, Sub-category 1B

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H304 May be fatal if swallowed and enters airways H317 May cause an allergic skin reaction H413 May cause long lasting harmful effects to aquatic life
Prevention	P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P331 Do NOT induce vomiting. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More (-)-Caryophyllene Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

9 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	BETA-CARYOPHYLLENE 99% powder aly- 87-44-5 lk	5 G	Oct 31, 2023
Thailand	High Purity Beta-Caryophyllene CAS 87-44-5	1 KG	Aug 23, 2023
Indonesia	BETA CARYOPHYLLENE	1000 KG	Mar 16, 2026
Philippines	β-caryophyllene	0.5 L	Apr 17, 2026
Canada	BETA-CARYOPHYLLENE	1 KG	Mar 29, 2025
Sri Lanka	Beta-caryophyllene	1000.00 KG	Feb 14, 2025
Thailand	Beta Caryophellene	2 KG	Aug 23, 2023
United States	BETA-CARYOPHYLLENE 99% powder aly- 87-44-5 lk	5 KG	Dec 19, 2025
Germany	BETA-CARYOPHYLLENE 99% powder aly- 87-44-5 lk	5 KG	Aug 10, 2024

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Supplier Name	Details
High Purity Beta-Caryophyllene CAS 87-44-5	/	Shandong zhishang chemical Co.,Ltd	Inquiry
BETA-CARYOPHYLLENE 99% powder aly- 87-44-5 lk	Agricultural Grade/99	SHANDONG LOOK CHEMICAL CO.,LTD	Inquiry
BETA-CARYOPHYLLENE	/99.00	HANGZHOU LEAP CHEM CO., LTD.	Inquiry
(-)-trans-Caryophyllene 99% high quality see COA KANBEI	Industrial Grade/99	Henan Lihao Chem Plant Limited	Inquiry
BETA-CARYOPHYLLENE 99% high purity certified Professional producer Greenbo	Food Grade/99	Greenbo Biochem	Inquiry

Hot Related Products



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.