Loperamide hydrochloride Dideu
1 Inquiries
34552-83-5
shanghai
25KG/Drum
2026-01-25
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceLoperamide hydrochloride is an opiate receptor agonist for the treatment of diarrhea.
Loperamide hydrochloride is a hydrochloride obtained by combining loperamide with one equivalent of hydrochloric acid. Used for treatment of diarrhoea resulting from gastroenteritis or inflammatory bowel disease. It has a role as a mu-opioid receptor agonist, an antidiarrhoeal drug and an anticoronaviral agent. It contains a loperamide(1+).|Loperamide Hydrochloride is the hydrochloride salt form of loperamide, a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity. Loperamide acts on the mu-receptors in the intestinal mucosa. This leads to a decrease in gastrointestinal motility by decreasing the circular and longitudinal smooth muscle activity of the intestinal wall. This slows intestinal transit and allows for more water and electrolyte absorption from the intestines. Loperamide is not significantly absorbed from the gut and does not cross the blood-brain barrier. Therefore it has no central nervous system effects.|One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.Basic Info-
Product Name:
Loperamide hydrochloride
Other Name:1-Piperidinebutanamide,4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-,hydrochloride (1:1);1-Piperidinebutanamide,4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-,monohydrochloride;4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinobutyramide hydrochloride;Loperamide hydrochloride;R 18553;Lopemin;Imodium;Loperazine;Lopodium;PJ 185;Arret;Imosec;Fortasec;Maalox Antidiarrheal;Imossel;Blox;Tebloc;Dissenten;Suprasec;Loperyl;Brek;Lopemid;Imodium A-D;NSC 696356
CAS No.:34552-83-5
Molecular Formula:C29H33ClN2O2.ClH
InChIKeys:InChIKey=PGYPOBZJRVSMDS-UHFFFAOYSA-N
Molecular Weight:513.5
Exact Mass:512.199707
EC Number:252-082-4
UNII:77TI35393C
NSC Number:759568|696356
NCI Thesaurus Code:C1584
HScode:29333990
Categories:
Characteristics-
PSA:
43.8
XLogP3:5.82790
Appearance:Crystals, practically insoluble in water
Density:1.1905 (rough estimate)
Melting Point:222-223 °C
Boiling Point:647.2ºC at 760 mmHg
Flash Point:345.2ºC
Water Solubility:>77 [ug/mL]
Storage Conditions:Store at RT
Toxicity:LD50 in mice (mg/kg): 75 s.c.; 28 i.p.; 105 orally; in rats (mg/kg): 185 orally (Niemegeers)
Collision Cross Section:219.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
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Certifications:
ISO Certificate,REACH
">Company Profile -
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Australia
Loperamide hydrochloride
1 MT Dec 24, 2025 Post an enquiry for this product