Eptifibatide CAS 188627-80-7 / Plecanatide / Selank / dihexa / Semax / N acetyl selank / epitalon/Nad+
TDS 2 Inquiries
188627-80-7
Pharmaceutical Grade
99%
shenzhen
RL
0.05kg/box
Yes
2028-01-30
Peptide,retatrutide,Semaglutide
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Product Details
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Seller Information
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History Price
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Inquiry History
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DescriptionECHEMI Editorial ReferenceEptifibatide is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.Target: OthersEptifibatide is an anti-coagulant that selectively blocks the platelet glycoprotein IIb/IIIa receptor. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarus barbouri). It belongs to the class of the so called arginin-glycin-aspartat-mimetics and reversibly binds to platelets [1, 2].Certificates
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TDS
Basic Info-
Product Name:
Eptifibatide
Other Name:MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;Intrifiban;N6-(AMinoiMinoMethyl)-N2-(3-Mercapto-1-oxopropyl)-L-lysylglycyl-L-.alpha.-aspartyl-L-tryptophyl-L-prolyl-L-cysteinaMide Cyclic (16)-Disulfide;3-Mercaptopropionyl-HoMoarg-Gly-Asp-Trp-Pro-Cys-NH2
CAS No.:188627-80-7
Molecular Formula:C35H49N11O9S2
InChIKeys:CZKPOZZJODAYPZ-UHFFFAOYSA-N
Molecular Weight:831.96
Exact Mass:831.315613
EC Number:1312995-182-4
DSSTox ID:DTXSID7046673
Categories:
Characteristics-
PSA:
377 Ų
XLogP3:log Kow = -4.33 (est)
Density:1.6±0.1 g/cm3
Refractive Index:1.735
Water Solubility:In water, 1108 mg/L at 25 °C (est)
Storage Conditions:Eptifibatide should be refrigerated at between 2-8 °C and protected from light until administration.|Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20 °C. Store with desiccant. /Eptifibatide acetate/
Vapor Pressure:1.78X10-40 mm Hg at 25 °C (est)
Henrys Law Constant:Henry's Law constant = 9.88X10-34 atm-cu m/mol at 25 °C (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 6.79X10-10 cu cm/molec-sec at 25 °C (est)
Research-
Class:
Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator
Status:Research compound — Not FDA approved
Mechanism:A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.
EC50 (HGF Binding KD):65 pM
Activity note:Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).
Source:Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.
Clinical Development:
References-
PubChem:UNII:Literature:
Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status
Disclaimer:Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Hazard IdentificationClassification of the substance or mixture
Specific target organ toxicity â single exposure, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H370 Causes damage to organs
Precautionary statement(s) Prevention P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P308+P316 IF exposed or concerned: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Peptide,retatrutide,Semaglutide
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Location:
Room 2008, 20th Floor, Unit 2, Building 15, No. 152, Dongsanmalu, Guancheng Hui District, Zhengzhou City, Henan Province
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Average lead Time:
15 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2024
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Weekly Price
The chart shows the price trend of the product in the past 12 months.
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Uzbekistan
Eptifibatide
60 G Dec 10, 2023
India
Eptifibatide
10 G May 13, 2026 Post an enquiry for this product
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