Hot Sale Ara290 Dsip VIP Dihexa Epitalon Glutathione Ghk-Cu Kpv Ll37 Melanotan2 Nad+ Oxytocin Pnc27 Selank Semax Ss31 Snap-8 with High Purity and Lowe
41 Inquiries
9004-61-9
Research Grade
98%
shanghai
rxc
5mg 10mg 15mg 20mg 30mg 40mg
2026-02-22
peptide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial Referencehyaluronic acid: A glycosaminoglycan(mucopolysaccharide) that ispart of the matrix of connective tissue.Hyaluronic acid binds cells togetherand helps to lubricate joints.It may play a role in the migration ofcells at wounds; this activity ceaseswhen hyaluronidase breaks downhyaluronic acid. ChEBI: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates.Basic Info
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Product Name:
Hyaluronic acid
Other Name:Hyaluronic acid;Mucoitin;Luronit;Hyaluronan;Sepracoat;ACP gel;ACP;ACP (polysaccharide);Durolane;Hylartil;Synvisc;Sofast;HA 9;Hylan G-F 20;Genzyme 9983;Hyalofill;Hy 20;Hyaluronsan HA-F;Hyalobarrier gel;Chlamyhyaluronic acid;Q 5AQ;Cystitat;Hyal;Hyruan Plus;Sepragel Sinus;Bio Hyaluro 9;HA-LF;Nutra-HAF;Hyaluronsan HA-LF;Hyaluronsan HA-L 510;Hyaferm;Macronan;FCH-A;Voluma;Biohyalo 12;Juvederm;Juvederm Voluma;Aquify;FCH 120;Hyalo-Oligo;Hyal-Joint;HA-LQ;Xiloial;Amalian I;Amalian II;Amalian III;Amalian Lips;Viscofill Basic;Viscofill Medium;Viscofill Extra;FCH 9;FUH-SU;Hyalorigo;Fluka 53747;PU 98;Mesolis;Emervel;PrimalHyal 300;Juvederm Ultra III;HyStem-C;Ialuset;Excellentha;Elevess;Restylene;Hyalrepair 07M;Hyalrepair 02;Hyacare 50;Hyalofemme;Belotero Balance;Perlane-L;Restylane-L;Hyalobarrier;Termira Auxigel;Oralvisc;Hyaluronsan HA-LF-P;Hilo Komod;Blepharogel;HA 700K1;Modelishape;Eschelissoft;Jolidermis 18;Gel 200;Gel-One;Revie reform;Bellcontour Gvisc;Juvederm Volbella XC;FCH 201P;Gengigel;HAO 1025;Tastex Hyalu 04;9039-38-7;29382-75-0;37243-73-5;165324-65-2;953845-54-0;953845-55-1;953845-56-2;953845-57-3;1257406-45-3;1357910-24-7;1444006-49-8;1623804-64-7;1623804-65-8
CAS No.:9004-61-9
Molecular Weight:403.31
EC Number:232-678-0
HScode:3004909090
Categories:
Characteristics-
PSA:
399.71000
XLogP3:-8.49480
Appearance:White Lyophilized Powder
Density:1.78 g/cm3
Boiling Point:1274.4ºC at 760 mmHg
Flash Point:724.5ºC
Refractive Index:1.666
Water Solubility:soluble in water.H2O: 5 mg/mL, clear, colorless
Storage Conditions:−20°C
Research-
Class:
Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator
Status:Research compound — Not FDA approved
Mechanism:A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.
EC50 (HGF Binding KD):65 pM
Activity note:Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).
Source:Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.
Clinical Development:
References-
PubChem:UNII:Literature:
Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status
Disclaimer:Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
peptide
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Location:
south road and north road
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2022
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Inquiry History41 Inquiries
Country Product Purchase Quantity Date Posted
India
Hyaluronic acid
1.00 MT Dec 13, 2023
India
Hyaluronic acid
5.00 KG Jan 19, 2024
India
Hyaluronic acid
15.00 MT Nov 10, 2023
United States
Hyaluronic acid
100 G May 11, 2026
Germany
Hyaluronic Acid
500 KG Sep 4, 2025
Brazil
Hyaluronic Acid
2 Aug 19, 2025
Peru
Singjoint Hyaluronic Acid
1 KG Jun 9, 2025
Nicaragua
Hyaluronic Acid
10 May 14, 2025
Russia
hyaluronic acid
100 KG Apr 22, 2025
Vietnam
Oligo sodium hyaluronate
50 KG Apr 17, 2025
India
Hyaluronic Acid
10 KG Nov 18, 2024
Egypt
Hyaluronic Acid
1 KG Jan 30, 2024
Egypt
Hyaluronic Acid cas99% white powderHyaluronic Acid
50 Jan 17, 2024
Indonesia
Hyaluronic acid
2 KG Jan 9, 2024
India
Hyaluronic acid
10.00 KG Jan 5, 2024
United Kingdom
Hyaluronic acid 99% Powder Pharmacy Grade C14H22NNaO11 Top Purity Senwayer
1 KG Nov 6, 2023
Netherlands
Low molecular weight hyaluronic acid
100 Sep 18, 2023
United Kingdom
Hyaluronic Acid
1 KG Mar 7, 2026
United Arab Emirates
Hyaluronic Acid
120 KG Sep 28, 2025
Mexico
Hyaluronic Acid
10 Aug 21, 2025 Post an enquiry for this product
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Shandong Runxin Biotechnology Co. , Ltd.