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Home > Biochemical Engineering > Polypeptide > HKPao for Sale > AP2 Adipotide Fast delivery High purity After Sales Assured Top rated
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AP2 Adipotide Fast delivery High purity After Sales Assured Top rated

20 Inquiries

Unit Price:

$20-25/G FOB

Get Latest Price
CAS No.:

859216-15-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

GUANGZHOU

Brand:

SH

Packaging:

2 mg/vial 5 mg/vial

Price valid (until):

2027-12-24

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Peptides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  



                                      Sales manager:Evelyn
                                   whatsapp:+1 608 209 3424
                                      Email:Sales03@adsh.top Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 1


    Fat-Targeting Pro-Apoptotic Peptide (FTPP) is a substance that binds to specific proteins (such as inhibitory proteins and annexin A2) on the surface of vascular endothelial cells in white adipose tissue. This substance consists of two functional domains: a targeting domain responsible for precisely identifying blood vessels in adipose tissue; and a pro-apoptotic domain that, upon entering the cell, disrupts the mitochondrial membrane, inducing apoptosis of vascular endothelial cells, cutting off the blood supply to adipose tissue, leading to atrophy or death of fat cells due to nutrient deficiency, ultimately achieving the goal of reducing fat.

    Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 2 Main Functions and Related Research
    Animal studies have shown that obese rhesus monkeys treated with Adipotide experienced an average weight loss of 11% after several weeks, with fat reduction primarily concentrated in areas associated with metabolic diseases, such as the abdomen; obese rats showed a 30% weight loss after 28 days of treatment. Preliminary human studies are consistent with animal studies, indicating that Adipotide can directly target fat accumulation sites for rapid and precise fat reduction.
    After using Adipotide, experimental animals showed significantly improved insulin sensitivity, which has potential implications for improving metabolic disorders such as diabetes. Human studies have also observed positive effects of Adipotide on metabolic health indicators.
    Potential Anti-Cancer Effects: The peptide can inhibit the growth of cancer cells by blocking their blood supply without damaging healthy tissue. It has shown some potential in studies of cancers such as prostate cancer, and its anti-angiogenic effect aligns with anti-angiogenic strategies in cancer research.
    Differences from Traditional Weight Loss Methods
    Compared to dieting and exercise, which are fundamental to weight management but require long-term commitment and are difficult to target stubborn fat, Adipotide can reduce localized fat more precisely and potentially faster.

    Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 3
    Compared to surgical methods: While surgical procedures such as liposuction are effective, they are invasive, high-risk, and expensive. Adipotide is a non-invasive therapy with less trauma to the body.
    Compared to other weight-loss peptides: Unlike peptides that suppress appetite or boost metabolism, Adipotide directly acts on fat cells, offering a unique weight-loss mechanism.

    Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 4

    The Importance of Peptides:
    Many active substances in the human body exist in the form of peptides. Peptides are involved in various areas of the human body, including hormones, nerves, cell growth, and reproduction. Their importance lies in regulating the physiological functions of various systems and cells in the body, activating related enzyme systems, promoting the permeability of intermediate metabolic membranes, or controlling DNA transcription or influencing the synthesis of specific proteins, ultimately producing specific physiological effects. Peptides are important substances involved in various cellular functions of the human body. Peptides can be synthesized within cells and regulate their functional activities. Peptides act as neurotransmitters to transmit information in the body. Peptides can also act as transport vehicles in the body, delivering various nutrients, vitamins, biotin, calcium, and trace elements—substances beneficial to the human body—to cells, organs, and tissues. Peptides are important physiological regulators in the human body, capable of comprehensively regulating physiological functions, enhancing and promoting physiological activities, and possessing important biological functions.

    Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 5

    Company Introduction
    Shanxi An Da Si Hai Technology Co., Ltd. is a professional manufacturer of various peptide products and chemical raw materials.
    We have a dedicated R&D team and a reliable, efficient logistics team to ensure you receive high-quality products safely and promptly. Our customers come from countries including the United States, Europe,
    Europe, Japan, South Korea, and India. Most of our main products are in stock and ready for immediate shipment. Please let us know the specific quantity you need, and we will offer you the most competitive price. Feel free to contact us for more information.

    We offer various types of peptides,are widely used in life science research, drug discovery, cosmetics, anti-aging medicine, and functional health industries.about the peptides,we can provide the good quality,the good price.Customers who have ordered our products(peptides)have had very good feedback.
    World wide relaible buyers can contact us about the peptides.

    Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 6 Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 7

    Items Specifications
    Product Name Adipotide
    CAS NO 859216-15-2
    form Solid freeze-dried powder
    Molecular formula C111H206N36O28S2
    Molecular weight 2557.21

    Shop AP2 Adipotide Fast delivery High purity After Sales Assured Top rated-Detailed Image 8

    ECHEMI Editorial Reference

    Adipotide is a synthetic chimeric peptidomimetic composed of a prohibitin-targeting peptide and a pro-apoptotic peptide sequence. Its defined structure, commonly represented as CKGGRAKDC-GG-D(KLAKLAK)₂, combines a vascular-targeting domain with a pro-apoptotic domain. As a specialized peptide research and pharmaceutical raw material, Adipotide is suitable for biochemical research, analytical studies, and pharmaceutical development.

    Basic Info
    Product Name:

    HKPao

    Other Name:

    D-Lysine, L-cysteinyl-L-lysylglycylglycyl-L-arginyl-L-alanyl-L-lysyl-L-α-aspartyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-;Adipotide Powder;Weight Loss Peptides Adipotide Adipotide Ftpp;HKPao;Adipotide (FTPP) 5mg 10mg;Prohibitin-targeting peptide 1

    CAS No.:

    859216-15-2

    Molecular Formula:

    C111H206N36O28S2

    InChIKeys:

    GZESIPHLGJDZRG-XRIURATCNA-N

    Molecular Weight:

    2557.21

    EC Number:

    200-001-8

    Categories:

    Polypeptide

    Characteristics
    Density:

    1.40±0.1 g/cm3(Predicted)

    Research
    Class:

    Chimeric peptidomimetic (fat-targeting vascular disruptor)

    Status:

    Research compound — Not FDA approved, clinical development discontinued

    Mechanism:

    A synthetic chimeric peptide composed of a fat-vascular-targeting cyclic peptide (CKGGRAKDC) linked via a GG spacer to a pro-apoptotic peptide (KLAKLAK)2. Adipotide selectively binds prohibitin in the vasculature of white adipose tissue, then delivers the pro-apoptotic domain to induce vascular disruption, causing fat tissue death. In primate studies (2011), it produced significant weight loss (~11%) but also caused renal toxicity, leading to development discontinuation.

    Activity note:

    Adipotide is not a receptor agonist. It functions as a targeted vascular disruptor. Functional activity is measured by tissue-specific apoptosis, not traditional EC50.

    Source:

    PubChem: Adipotide (CID 163360068); Kolonin MG, et al. Sci Transl Med. 2004;6(148):148ra16.DOI

    References
    PubChem:

    PubChem

    Disclaimer:

    Adipotide is NOT FDA-approved or EMA-approved. It is a research compound only. Clinical development was discontinued due to renal toxicity observed in primate studies. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides

    Location:

    Shanxi An Da Si Hai Technology Co., Ltd.

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Less than 5

    Year of Establishment:

    2025

  • Inquiry History
    20 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Adipotide

    10 MG Jun 6, 2025
    United States

    adipotide

    10  May 30, 2025
    United States

    Adipotide

    2 BOU Nov 26, 2024
    Germany

    Adipotide

    100  Nov 6, 2024
    Mexico

    adipotide

    5 G Sep 8, 2025
    United States

    adipotide

    10 MG Aug 21, 2025
    United States

    adipotide

    15 MG Jun 15, 2025
    Germany

    Adipotide FTPP

    200 MG Oct 18, 2024
    United States

    adipotide

    1 KG Feb 24, 2026
    Philippines

    Adipotide

    10 PCS Oct 20, 2025
    United States

    ADIPOTIDE

    100 MG Jul 21, 2025
    Thailand

    adipotide

    100  Apr 23, 2025
    United States

    Adipotide

    10 G Apr 18, 2025
    United States

    Adipotide

    5 G Apr 12, 2025
    United States

    Adipotide

    5 MG Jan 9, 2025
    United States

    99% Purity Weight Loss Peptide Adipotide for Slimdown

    57 KG Nov 30, 2024
    United States

    Adipotide

    500 MG Nov 20, 2024
    United States

    Adipotide

    10 G Sep 25, 2024
    United States

    Adipotide 5mg 10vial kit

    1 MT Feb 25, 2024
    United States

    Adipotide CAS Weight Loss Peptides 859216-15-2 99% Purity CAS 859216-15-2 5mg 10mg 20mg vials

    15 MG Jun 15, 2025
    Post an enquiry for this product
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