Cost-effective sourcing of 99% pure Tamsulosin CAS 106133-20-4 raw material
1 Inquiries
106133-20-4
Pharmaceutical Grade
99%
shanghai
1kg/bag;25kg/Cardboard Drum
2026-03-03
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTamsulosin hydrochloride is the first in the class of potent and selective α- 1Aadrenoceptor antagonists introduced for the treatment of dysuria associated with benign prostatic hypertrophy (BPH). In a clinical study, significant improvement in irritative and obstructive symptoms has been reported for tamsulosin treated patients with BPH. ln vitro studies in human penile erectile tissue and vas deferens indicated that tamsulosin may be ofuse in treating male sexual dysfunction.Tamsulosin (Flo
Solid
Tamsulosin is a 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide that has (R)-configuration. A specific alpha1 adrenoceptor antagonist used (generally as its hydrochloride salt, tamsulosin hydrochloride) in the treatment of prostatic hyperplasia, chronic prostatitis, urinary retention, and help with the passage of kidney stones. It has a role as an alpha-adrenergic antagonist and an antineoplastic agent. It is a conjugate base of a tamsulosin(1+). It is an enantiomer of an ent-tamsulosin.|Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow. Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension. Tamsulosin was first approved by the FDA on April 15, 1997.|Tamsulosin is an alpha-Adrenergic Blocker. The mechanism of action of tamsulosin is as an Adrenergic alpha-Antagonist.|Tamsulosin is a selective alpha-1a adrenergic antagonist used in the therapy of benign prostatic hypertrophy. Tamsulosin therapy is associated with a low rate of serum aminotransferase elevations, but clinically apparent acute liver injury due to tamsulosin is very rare.|A sulfonamide derivative and adrenergic alpha-1 receptor antagonist that is used to relieve symptoms of urinary obstruction caused by BENIGN PROSTATIC HYPERPLASIA.Basic Info-
Product Name:
Tamsulosin
Other Name:Benzenesulfonamide,5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-;Benzenesulfonamide,5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-,(R)-;5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide;Amsulosin;Tamsulosin;(-)-Tamsulosin;(R)-Tamsulosin;(R)-5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide;Tulosin;Contiflo OD
CAS No.:106133-20-4
Molecular Formula:C20H28N2O5S
InChIKeys:InChIKey=DRHKJLXJIQTDTD-OAHLLOKOSA-N
Molecular Weight:408.51
Exact Mass:408.51
EC Number:1533716-785-6
UNII:G3P28OML5I
DSSTox ID:DTXSID3023631
ATC Code:G04CA02|G - Genito urinary system and sex hormones
HScode:2935009090
Categories:
Characteristics-
PSA:
108
XLogP3:2.7
Appearance:Solid
Density:1.191±0.06 g/cm3(Predicted)
Melting Point:228-230 °C
Boiling Point:595.5±60.0 °C(Predicted)
Flash Point:313.9±32.9 °C
Refractive Index:1.553
Water Solubility:Sparingly soluble in water
Storage Conditions:Store at 25 deg C (77 deg F); excursions permitted to 15-30 deg C (59-86 deg F).
Vapor Pressure:3.96X10-11 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 4.95X10-15 atm-cu m/mol at 25 °C (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 1.55X10-10 cu cm/molec-sec at 25 °C (est)|MW 444.97. MP 228-230 °C; Specfic optical rotation: -4.0 deg at 24 °C/D (c = 0.35 in methanol) /Tamsulosin hydrochloride/
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
India
Tamsulosin
50 G Oct 15, 2023 Post an enquiry for this product