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Cost-effective sourcing of 99% pure Trimethoprim CAS 738-70-5 raw material

17 Inquiries

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CAS No.:

738-70-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Packaging:

1kg/bag;25kg/Cardboard Drum

Price valid (until):

2026-03-04

Contact Supplier

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Xi'an Honest BioEngr Co.,Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Superiority

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request.

Our service

1. Reply your inquiry in 24 working hours.
2. Customized design is available. OEM are welcomed.
3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
staff.
4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.

Shop High-purity raw material Vortioxetine CAS 508233-74-7 at competitive pricing-Detailed Image 1

FAQ

1.: Are you a factory or trading company
We are the integration of factory and trade.

2.: How is the quality I want to test.
Before production and extraction, we will test all raw materials.Quality is our top priority.All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.

3.: Can I get a Free sample
Yes,We can provide free samples.For most products we can provide you a free sample, You only need to pay for Shipping. Plesae be free to consult our salesman.
For a larger quantity, we always support you with better price, and we will have some discount in some especial days.

4. : What's your main payment method
T/T (Bank transfer), Wechat,Alipay,Credit card payment.

5. : Have you received my payment How long will it take
Generally, we can receive your payment the next day, and we will inform you as soon as we receive your payment.
After confirmation payment, we will send out package

6.:When will you sent out the goods after successful payment
Normally the order will be delivery within 1-3 days after the order confirmed, except the customized products.

7.:What modes of transportation do you have to choose
We cooperate with HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post ,sea transportation etc.
And with the SAFE SHIPPING in each country, you can receive the goods smoothly.It is fast and safe method.

8.:How long does it take to the goods arrived
It is Depending on your location:
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, HKEMS,Netherlands post.
For large order, please allow 5-8 days by Air, 20-35 days by Sea
At the same time, we have warehouses in Germany and California, and some orders can be sent directly from Germany or California.

9.:How is the goods packed
We usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.

10.: How can I get a discount
Our products have already given you a discount, and the price is favorable. Orders above $1,000 can enjoy 95% discount, transportation discount or additional sample products. Therefore, for larger quantities, we always support better prices.

11.: How to proceed order
Please Let me konw the product you are looking for,quantity and the destination country wihch help me to give you a right price;
After you confirm all details of order, pay money in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.

12.:When will I receive the shipping number Where I can check status of my order
After the goods are sent out, our staff will send you the shipping number via email, online or WhatsApp ASAP.You can also check the status online on 17track.

13.:Is a signature required for the shipping?
Our shipping method requires no signature from your side upon delivery.

ECHEMI Editorial Reference

Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections.Target: DHFRTrimethoprim (TMP), an inhibitor of dihydrofolate reductase, decreases the level of tetrahydrofolate supplying one-carbon units for biosynthesis of nucleotides, proteins, and panthotenate. TMP caused induction of DnaK, DnaJ, GroEL, ClpB, and IbpA/B Hsps. Among these Hsps, IbpA/B were most efficiently induced by TMP and coaggregated with the insoluble proteins [
Trimethoprim is an odorless white powder. Bitter taste. (NTP, 1992)|Solid
Trimethoprim is an odorless white powder. Bitter taste. (NTP, 1992)|Trimethoprim is an aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge. It has a role as an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, a xenobiotic, an environmental contaminant, a drug allergen, an antibacterial drug and a diuretic. It is a member of methoxybenzenes and an aminopyrimidine.|Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary tract infections. It is structurally and chemically related to [pyrimethamine], another antifolate antimicrobial used in the treatment of plasmodial infections.|Trimethoprim is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.|Sulfamethoxazole with trimethoprim is a fixed antibiotic combination that is widely used for mild-to-moderate bacterial infections and as prophylaxis against opportunistic infections. Like other sulfonamide-containing medications, this combination has been linked to rare instances of clinically apparent acute liver injury.|Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)|A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.

Basic Info

Product Name:

Trimethoprim

Other Name:

2,4-Pyrimidinediamine,5-[(3,4,5-trimethoxyphenyl)methyl]-;Pyrimidine,2,4-diamino-5-(3,4,5-trimethoxybenzyl)-;5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine;BW 56-72;2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine;Syraprim;Trimethoprim;NIH 204;2,4-Diamino-5-(3′,4′,5′-trimethoxybenzyl)pyrimidine;Trimethioprim;Trimetoprim;Triprim;Trimpex;Trimanyl;Instalac;Trimogal;Wellcoprim;Monotrim;Proloprim;Tiempe;Trimopan;Uretrim;NSC 106568;Infectotrimet

CAS No.:

738-70-5

Molecular Formula:

C14H18N4O3

InChIKeys:

InChIKey=IEDVJHCEMCRBQM-UHFFFAOYSA-N

Molecular Weight:

290.31800

Exact Mass:

290.32

EC Number:

212-006-2

UNII:

AN164J8Y0X

NSC Number:

757370|752719|106568

UN Number:

2811

DSSTox ID:

DTXSID3023712

NCI Thesaurus Code:

C908

Color/Form:

White to cream, crystalline powder

ATC Code:

J01EE01|J - Antiinfectives for systemic use

HScode:

2933599090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

105.51000

XLogP3:

0.9

Appearance:

Trimethoprim is an odorless white powder. Bitter taste. (NTP, 1992)

Density:

1.252 g/cm3

Melting Point:

199-203 °C

Boiling Point:

526ºC at 760 mmHg

Flash Point:

271.9ºC

Refractive Index:

1.600

Water Solubility:

<0.1 g/100 mL at 24 ºC

Storage Conditions:

2-8ºC

Toxicity:

LD50 orally in mice: 7000 mg/kg (Yamamoto)

Odor:

Odorless

Taste:

Bitter

PKA:

7.12(at 20 °C)

Dissociation Constants:

7.12 (at 20 °C)|pKa= 7.12 (conjugate acid)

Collision Cross Section:

170.8 Å² [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|171.2 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|172.89 Å² [M+H]+

Air and Water Reactions:

Insoluble in water.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Profile:

This compound readily forms salts with acids. (NTP, 1992).

See More Trimethoprim Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Trimethoprim Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10

Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA

Payment Terms:
TT against copy of documents,100% TT in advance

Average lead Time:
30

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2023

Company Profile

Inquiry History

17 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Trimethoprim	50 KG	Dec 16, 2025
India	Trimethoprim	25 KG	Sep 13, 2024
Ecuador	TRIMETOPRIM	25 KG	May 29, 2024
Pakistan	Trimethoprim	300 KG	Apr 8, 2024
Peru	Trimethoprim	2.00 MT	Nov 7, 2023
India	Trimethoprim	3000 KG	Oct 1, 2023
Paraguay	Doxycycline hyclata	150.00 KG	Sep 25, 2025
Paraguay	Chlorhexidine digluconate	400.00 KG	Sep 25, 2025
Paraguay	Praziquantel	100.00 KG	Sep 26, 2025
Paraguay	Benzidamine hidrochloride	500.00 KG	Sep 25, 2025
Paraguay	Choline chloride	200.00 KG	Sep 25, 2025
Paraguay	Trichlorfon	200.00 KG	Sep 25, 2025
Paraguay	Azepromacine maleate	10 KG	Sep 25, 2025
Paraguay	Tylosin tartrate	100.00 KG	Sep 26, 2025
Paraguay	Copper disodium EDTA	200.00 KG	Sep 26, 2025
Paraguay	Fipronil	800.00 KG	Sep 26, 2025
Paraguay	Dichloromethane	4000.00 KG	Sep 25, 2025

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