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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > MOTS-c for Sale > Factory direct sales/High quality/High purity/Mots-c
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Factory direct sales/High quality/High purity/Mots-c

TDS 132 Inquiries

Unit Price:

$75/UNIT FOB

Get Latest Price
CAS No.:

1627580-64-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Guanzghou

Brand:

Guangsheng

Packaging:

10mg*10vials; 15mg*10vials; 20mg*10vials; 40mg*10vials

Price valid (until):

2030-01-07

Company Type:
Trader
Location:
China
Qualification:
Main Products:

beaty prodt

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Name:  Lynn
    Wechat:  15914422644

    Tel:+86  15914422644

    Whatsapp: +852 6252 8290

    Email:    guangsheng 5   @zgguangsheng.com

    Product Description

    MOTS-c is a mitochondrial-derived peptide consisting of amino acids. This bioactive peptide has attracted research interest for its potential role in cellular metabolism regulation. The synthetic version maintains identical sequence to the native peptide while ensuring high purity and batch-to-batch consistency.

    Key Features

    •  High-purity grade suitable for research applications
    • Structural verification by mass spectrometry and HPLC
    • Stable lyophilized form for long-term storage
    • Custom modifications available (e.g., labeling, conjugation)

    Research Applications

    • Metabolic pathway studies

    • Cellular energy regulation research

    • Mitochondrial function investigations

    • Biochemical mechanism exploration

    Quality Assurance

    • Comprehensive Certificate of Analysis (COA)

    • Sterility testing available upon request

    • Endotoxin levels <1.0 EU/mg

    • Packaging Options

      Available in:

      • 1mg, 5mg, 10mg vials

      • Bulk quantities (custom packaging)

      • Special temperature-controlled shipping

      Important Notes

      • For research use only (not for human or veterinary use)

      • Researchers must comply with all applicable regulations

      • Proper handling procedures required

      For detailed technical specifications or custom synthesis inquiries, please contact our scientific team.

    • MOTS-c is a novel mitochondrial-derived peptide consisting of  amino acids that has emerged as a subject of significant scientific interest. As a naturally occurring peptide encoded in the mitochondrial genome, our synthetic version replicates the exact biological sequence while ensuring pharmaceutical-grade purity. The product undergoes multiple purification steps to remove impurities and maintain structural integrity, making it ideal for rigorous research applications.



     About Us 


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      Product Detail  


    1. Molecular & Physical Properties

    • Amino Acid Sequence: Ala-His-Lys-Cu, formed by chelating the tripeptide alanyl-histidyl-lysine with copper ions.
    • Purity: ≥99% (HPLC verified), ensuring high bioactivity and minimal impurities.
    • Physical Appearance: Deep blue lyophilized powder, highly water-soluble for easy formulation into solutions, creams, or injectables.
    • Stability: Optimal storage at -20℃; stable for 24 months when sealed from light and moisture; avoid high temperatures to prevent copper ion dissociation.

    2. Core Biological Mechanisms

    • Collagen & Elastin Synthesis: It upregulates the expression of TGF-β and matrix metalloproteinase inhibitors (TIMPs), stimulating fibroblasts to produce type I/III collagen and elastin. This enhances skin elasticity, reduces fine lines, and improves skin texture.
    • Antioxidant & Anti-inflammatory Effects: The copper ion moiety scavenges free radicals (e.g., superoxide anion, hydroxyl radicals) to mitigate oxidative stress. It also inhibits NF-κB pathways, reducing the release of pro-inflammatory cytokines (TNF-α, IL-6) and alleviating tissue inflammation.
    • Hair Follicle Activation: It extends the anagen (growth) phase of hair follicles, increases dermal papilla cell proliferation, and improves microcirculation around hair follicles, which aids in reversing hair miniaturization associated with androgenetic alopecia.
    • Wound Healing Acceleration: By promoting angiogenesis and fibroblast migration, it speeds up granulation tissue formation and epithelialization, shortening recovery time for acute and chronic wounds (e.g., burns, diabetic ulcers).

    3. Application Scenarios

    • Dermatological Cosmetics: Added to anti-aging serums, creams, and masks to improve skin firmness, fade wrinkles, and repair photodamaged skin.
    • Trichological Research: Used in topical formulations or scalp injections for androgenetic alopecia treatment and hair regrowth studies.
    • Regenerative Medicine: Applied in wound care dressings and tissue engineering scaffolds to enhance skin and soft tissue repair.
    • Laboratory Research: Serves as a tool compound for studying copper peptide biology, oxidative stress, and tissue regeneration mechanisms.

    4. Safety & Advantages

    • Non-immunogenic, with no reported allergic reactions or systemic side effects in topical use.
    • Biodegradable, breaking down into natural amino acids and copper ions that are metabolized by the body.
    • Compatible with most cosmetic and pharmaceutical excipients (e.g., hyaluronic acid, glycerin), suitable for multi-component formulations.


      Product Detail  


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    ECHEMI Editorial Reference
    MOTS-C Synthetic is a single, non-glycosylated polypeptide chain containing 16 amino acids, having a molecular mass of 2174.59 Dalton and a Molecular formula of C10H152N280O22 S2.

    Certificates

    Basic Info
    Product Name:

    MOTS-c

    Other Name:

    MOTS-c;L-Arginine, L-methionyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-α-glutamyl-L-methionylglycyl-L-tyrosyl-L-isoleucyl-L-phenylalanyl-L-tyrosyl-L-prolyl-L-arginyl-L-lysyl-L-leucyl-;MOTS-C acetate;Cosmetic Peptide Mots-C;MOTS-c POWDER;MOTS-c peptide;MOTS-c 5mg/10mg;H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

    CAS No.:

    1627580-64-6

    Molecular Formula:

    C101H152N28O22S2

    InChIKeys:

    WYTHCOXVWRKRAH-JIJBDQHHNA-N

    Molecular Weight:

    2174.62

    Exact Mass:

    2174.1110958

    EC Number:

    200-001-8

    Color/Form:

    Solid lyophilized powder

    Categories:

    Other Chemical Drugs

    Characteristics
    Density:

    1.44±0.1 g/cm3(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    Mitochondrial-derived peptide (MDP), 16-amino-acid peptide

    Status:

    Research compound — Not FDA approved

    Mechanism:

    MOTS-c (mitochondrial ORF of the twelve S rRNA-c) is a 16-amino-acid peptide encoded by the mitochondrial genome (not nuclear DNA). It is a mitochondrial-derived peptide that regulates metabolic homeostasis by activating the AMPK/PGC-1\u03b1 pathway, improving insulin sensitivity, and enhancing exercise capacity. MOTS-c crosses the blood-brain barrier and has been shown to reduce body weight and improve glucose tolerance in preclinical models.

    Activity note:

    MOTS-c does not act via a traditional receptor. It functions as a metabolic regulator, activating AMPK. Functional effects are observed at micromolar concentrations in cell-based assays.

    Source:

    Lee C, et al. Cell Metab. 2015;21(3):443-454. MCE: MOTS-c (CAS 1627580-64-6).DOI

    References
    PubChem:

    PubChem

    Disclaimer:

    MOTS-c is NOT FDA-approved or EMA-approved. It is a research compound only. All data are from preclinical (cell/animal) studies; no human clinical trials have been completed. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    beaty prodt

    Location:

    Yongtai Jinli City Plaza, Baiyun District, Guangzhou City, Guangdong Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    30

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2023

  • Inquiry History
    132 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Mots-C CAS 1627580-64-6

    5 G Apr 26, 2026
    United States

    Bodygrowth Peptides CAS 1627580-64-6 MOTS-c (Human) Acetate peptides powder

    1 G Feb 23, 2026
    United States

    MOTS-c (Human) Acetate peptides powder

    1 G Mar 12, 2026
    Brazil

    MOTS-c 10mg Peptide Raw Material High Purity

    10 PCS Feb 17, 2026
    United States

    Mots-C

    1 KG Sep 12, 2025
    United Kingdom

    mots-c

    15 MG Aug 3, 2026
    United States

    Mots c

    10 MG Jul 23, 2026
    United States

    MOTS-c

    20 MG Jul 21, 2026
    Azerbaijan

    Mots-c

    5 G Jun 25, 2026
    United States

    MOTS-c

    500 MT Jun 22, 2026
    United States

    Mots-c

    1 MT Jun 16, 2026
    Australia

    MOTS-c 50mg

    30 PCS May 25, 2026
    United States

    Mots C

    4000 MG May 20, 2026
    China

    Mots-C

    10000 MT May 19, 2026
    Brazil

    most-C

    1 KG May 12, 2026
    Canada

    Mots-c

    1 KG Apr 23, 2026
    Greece

    MOTS-C

    10 G Apr 14, 2026
    Pakistan

    MOTS-C

    10 PCS Apr 6, 2026
    United States

    Mots-C

    10 MT Apr 4, 2026
    United States

    Mots-c

    100 MG Mar 29, 2026
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