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Mirodenafil   RC09973 buy - large image1
Mirodenafil   RC09973 buy - image1

Mirodenafil RC09973

3 Inquiries

Unit Price:

$1/KG EXW

Get Latest Price
CAS No.:

862189-95-5

Grade:

Pharmaceutical Grade

Content:

99%

Brand:

Royalchem

Packaging:

25kg/drum

Sample Available:

Yes

Price valid (until):

2030-01-01

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
14 days
Qualification:
Main Products:

Pharmaceutical intermediates

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Manufacturer: Hangzhou Royalchem Co.,LTD.

    Website:  www.cnroyalchem.com 

    Hangzhou Royalchem Co., Ltd. was founded by a senior team with profound professional backgrounds in the chemical field, focusing on providing comprehensive chemical products and services. Its business scope covers a wide range, including the sales of core chemical products such as pharmaceutical raw materials and intermediates, food/feed additives, specialty chemicals, dyes & pigments, new catalytic materials, chemical reagents, engineering plastics and synthetic resins. It also engages in the sales of daily chemicals, containers, and import-export business, meeting the needs of clients across multiple sectors. Leveraging the technical accumulation of its professional team and strict quality control, the company has established a stable cooperation network in domestic and international markets. It not only provides high-quality raw material support for industries but also promotes global chemical resource circulation through import-export operations. Adhering to the philosophy of "win-win cooperation," Hangzhou Royalchem Co., Ltd. takes professionalism and integrity as its cornerstone, and sincerely looks forward to working with global partners to drive high-quality development in the chemical industry.


    Hangzhou Royalchem Co., Ltd.  Is focus on services on CMO & CDMO

    Esterification, saponification, hydrolysis, alkylation, halogenation, acetylation, pressurized hydrogenation, and other reactions .


    Preparation and separation of various impurities .


    Development of preparation and purification production processes, salt conversion, liquid preparation post-treatment, etc.



    Items Specifications






    ECHEMI Editorial Reference
    Mirodenafil is a member of the class of pyrrolopyrimidines that is 3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one having a 5-{[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl}-2-propoxyphenyl group at positon 2, ethyl group at position 5, and a propyl group at position 7. It is a phosphodiesterase type 5 inhibitor which is used for the treatment of erectile dysfunction. It has a role as an EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor and a vasodilator agent. It is a sulfonamide, a pyrrolopyrimidine, a N-alkylpiperazine, a primary alcohol and an aromatic ether.|Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
    Mirodenafil (Mvix), a second-generation PDE5i, was launched in Korea in November 2007, and its orally dissolving film (Mvix S) was launched in December 2011. The product is available in tablet formulation or orally dissolving film of 50 and 100 mg. Mirodenafil has been approved only in Korea. Its pharmacokinetic profiles include a Tmax of 1.25 h, T1/2 of 2.5 h, and a IC50 for PDE5 of 0.34 nmol/L, which would confer a biochemical property of relatively high affinity (potency) for PDE5. While the pharmacokinetic profile is similar to that of sildenafil, mirodenafil appears to be 10 times more selective for PDE5 than sildenafil.

    Basic Info
    Product Name:

    MIRODENAFIL

    Other Name:

    5-Ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one;MIRODENAFIL;5-ethyl-2-[5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl-2-propoxyphenyl]-7-propyl-1H-pyrrolo[3,2-d]pyrimidin-4-one;4H-Pyrrolo[3,2-d]pyriMidin-4-one,5-ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-;Mirodenafil, >=98%;5-Ethyl-2-(5-{[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl}-2-propoxyphenyl)-7-propyl-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;MILONAFIL;Mirodenafil Solution, 100μg/mL

    CAS No.:

    862189-95-5

    Molecular Formula:

    C26H37N5O5S

    InChIKeys:

    MIJFNYMSCFYZNY-UHFFFAOYSA-N

    Molecular Weight:

    531.67

    Exact Mass:

    531.67

    EC Number:

    1533716-785-6

    UNII:

    504G362H0H

    Color/Form:

    White to off-white

    Categories:

    Inhibitor Drugs

    Characteristics
    Density:

    1.33

    Boiling Point:

    730.4±70.0 °C(Predicted)

    PKA:

    14.96±0.10(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceutical intermediates

    Location:

    Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou

    Payment Terms:

    TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    14 days

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    Less than 5

    Year of Establishment:

    2025

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Mirodenafil

    100 KG Jun 26, 2024
    Canada

    Mirodenafil

    1 KG Dec 2, 2024
    Indonesia

    Mirodenafil

    1 KG Sep 2, 2024
    Post an enquiry for this product

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