Safe shipment Nootropics Dihexa Peptide CAS 1401708-83-5 Raw Powder
TDS 53 Inquiries
1094-61-7
Pharmaceutical Grade
99%
shenzhen
HS
25kg drum
2026-04-03
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial Referenceβ-nicotinamide mononucleotide is an intermediate in NAD+ biosynthesis produced from nicotinamide (NAM) and phosphoribosyl pyrophosphate (PRPP) by nicotinamide phosphoribosyl transferase enzyme.
NMN zwitterion is a nicotinamide mononucleotide. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a conjugate base of a NMN(+). It is a conjugate acid of a NMN(-).|3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN.CertificatesBasic Info-
Product Name:
Nicotinamide mononucleotide
Other Name:Pyridinium,3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-,inner salt;Pyridinium,3-carbamoyl-1-β-D-ribofuranosyl-,hydroxide,5′-(dihydrogen phosphate),inner salt;Pyridinium,3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-,hydroxide,inner salt;3-Carbamoyl-1-β-D-ribofuranosylpyridinium hydroxide,5′-phosphate,inner salt;Nicotinamide mononucleotide;Nicotinamide ribonucleotide;NMN;Nicotinamide ribotide;β-NMN;Nicotinamide ribonucleoside 5′-phosphate;NMN (mononucleotide);β-D-NMN;27626-81-9;1140909-84-7
CAS No.:1094-61-7
Molecular Formula:C11H15N2O8P
InChIKeys:InChIKey=DAYLJWODMCOQEW-TURQNECASA-N
Molecular Weight:334.22
Exact Mass:334.056610
EC Number:214-136-5
UNII:2KG6QX4W0V
Categories:
Characteristics-
PSA:
166
XLogP3:-3.5
Storage Conditions:2-8°C
Collision Cross Section:165.2 Ų [M]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|165.2 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|167.13 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|166 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|165.8 Ų [M+H]+
Research-
Class:
Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator
Status:Research compound — Not FDA approved
Mechanism:A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.
EC50 (HGF Binding KD):65 pM
Activity note:Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).
Source:Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.
Clinical Development:
References-
PubChem:UNII:Literature:
Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status
Disclaimer:Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China
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Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2017
Company Certificates-
ISO
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ISO
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Inquiry History53 Inquiries
Country Product Purchase Quantity Date Posted 
Australia
NMN β-Nicotinamide Mononucleotide 1094-61-7 99.5% Uthever
50 KG Nov 17, 2023 
Philippines
β-NMN bulk powder 1094-61-7 Purity 99.9% food grade Beta Nicotinamide Mononucleotide powder
500 G Jul 17, 2025 
India
Beta-Nicotinamide Mononucleotide
1 KG Jan 19, 2026
India
NMN
1.00 KG Dec 21, 2023 
United States
β-Nicotinamide Mononucleotide (NMN)
1 G Aug 11, 2026
India
Nicotinamide mononucleotide (NMN)
300.00 KG Sep 4, 2026
India
Nicotinamide mononucleotide (NMN)
50.00 KG Aug 26, 2026 
Pakistan
Nicotinamide
500.00 KG Jul 24, 2026
India
Nicotinamide mononucleotide
50 G Apr 8, 2026
United States
NMN
100 G Mar 14, 2026
India
Niacinamide
75.00 KG Feb 25, 2026
Australia
NMN
1 KG Feb 21, 2026 
Indonesia
Nicotinamide mononucleotide NMN
1 KG Oct 13, 2025
Australia
NMN
1 KG Nov 1, 2024
United States
β-Nicotinamid Mononucleotide
1 KG Sep 26, 2024 
South Korea
b-NMN
1 KG May 30, 2024 
Vietnam
NMN
1 MT May 24, 2024
United States
NMN
1 MT Mar 7, 2024
Australia
NMN
50 KG Dec 12, 2023 
Peru
NMN
1 KG Nov 29, 2023 Post an enquiry for this product
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