2-Bromo-3'-chloropropiophenone Dideu

**Product Name: 2-Bromo-3'-chloropropiophenone**
**CAS No.: 34911-51-8**
**Molecular Formula: C₉H₈BrClO**
**Molecular Weight: 247.52 g/mol**
**Purity: ≥98% (HPLC/GC), customizable**
**Appearance: White to off-white crystalline powder**

**Product Overview**

2-Bromo-3'-chloropropiophenone is a versatile α-halogenated aryl ketone featuring dual halogen functionality with bromine at the alpha position and chlorine at the meta position of the phenyl ring. This strategically designed molecular architecture combines high reactivity of the α-bromo ketone moiety with the electron-withdrawing effect of the meta-chloro substituent, creating an exceptional bifunctional building block for complex organic synthesis. The compound's excellent crystallinity, controlled reactivity profile, and compatibility with diverse reaction conditions make it indispensable for pharmaceutical intermediates, agrochemical synthesis, and heterocyclic compound development requiring precise structural modifications and high-yield transformations.

**Main Applications**

**Pharmaceutical Intermediate Synthesis**
Critical building block for synthesizing bioactive molecules including antifungal agents, anticonvulsants, and CNS-active compounds. The α-bromo ketone functionality enables efficient construction of oxazoles, imidazoles, and other nitrogen-containing heterocycles essential for developing novel therapeutic agents targeting infectious diseases and neurological disorders.

**Agrochemical Manufacturing**
Essential intermediate for producing advanced herbicides, fungicides, and insecticides where the dual halogen substitution pattern provides enhanced bioactivity and environmental stability. Particularly valuable for developing selective crop protection agents with improved efficacy and reduced ecotoxicological impact.

**Heterocyclic Chemistry**
Versatile precursor for synthesizing diverse heterocyclic scaffolds including benzoxazoles, quinolines, and fused ring systems through cyclization reactions. The compound's bifunctional nature enables sequential transformations for constructing complex molecular architectures in medicinal chemistry programs and natural product synthesis.

**Organic Synthesis Building Block**
Key reagent for α-functionalization reactions, nucleophilic substitution, and cross-coupling processes in complex molecule assembly. The bromine atom serves as an excellent leaving group for Suzuki, Stille, and Negishi coupling reactions, while the ketone functionality enables aldol condensations and nucleophilic additions.

**Chemical Research & Development**
Valuable tool compound for investigating reaction mechanisms, stereoselective transformations, and catalytic processes in academic and industrial research laboratories. Used extensively in methodology development for new synthetic routes and green chemistry applications.

**Custom Synthesis & CRO Services**
High-demand intermediate for contract research organizations engaged in multi-step synthesis projects requiring halogenated aryl ketones as key structural components for drug discovery and specialty chemical development.

**Product Features**

- **High Purity Standard**: ≥98% analytical purity with strict control of residual solvents and trace impurities
- **Excellent Crystallinity**: Well-defined crystal structure ensures consistent reactivity and handling properties
- **Controlled Reactivity Profile**: Optimized halogen positioning enables selective transformations without unwanted side reactions
- **Superior Stability**: Stable under standard storage conditions with minimal degradation during extended periods
- **Good Solubility**: Soluble in common organic solvents including acetone, ethyl acetate, dichloromethane, and THF
- **Batch-to-Batch Consistency**: Rigorous quality control with comprehensive analytical documentation (HPLC, NMR, GC-MS)
- **Low Moisture Content**: <0.3% moisture ensures optimal performance in moisture-sensitive reactions

**Packaging & Storage**

**Packaging Options**: 100 g, 500 g, 1 kg, 5 kg, 25 kg HDPE drums with double-layer sealing under inert atmosphere; custom bulk packaging available
**Storage Conditions**: Store at 2-8°C in airtight containers, protected from light and moisture to maintain stability
**Shelf Life**: 24 months when stored under recommended conditions
**Transport**: Standard chemical shipment with moisture-proof packaging; temperature-controlled shipping recommended for extended transit periods

**Why Choose Us**

- **Specialized Fine Chemical Manufacturer**: Advanced synthesis technology with proprietary purification processes ensuring superior purity and consistent quality
- **Comprehensive Analytical Capabilities**: In-house laboratory with HPLC, GC-MS, NMR, FTIR, and elemental analysis for complete product characterization
- **Technical Expertise**: Dedicated organic chemists providing application support, synthetic route optimization, and custom development services
- **GMP Compliance**: Manufacturing facilities operating under Good Manufacturing Practices with full documentation and traceability systems
- **Scalable Production**: Flexible capacity from research quantities (grams) to industrial-scale (hundreds of kilograms) with consistent quality parameters
- **Global Supply Chain**: Established logistics network with customs clearance expertise serving customers worldwide with reliable delivery schedules
- **Custom Synthesis Services**: Ability to modify molecular structure or develop derivative compounds based on specific customer requirements

*Note: This product is intended for industrial and research use only. Handle with appropriate personal protective equipment in well-ventilated areas. All specifications subject to change without notice. Contact us for customized purity requirements, special packaging requests, or bulk pricing inquiries. Certificate of Analysis and Safety Data Sheet available upon request.*