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NR

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CAS No.:

23111-00-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Packaging:

25kg drum

Price valid (until):

2026-04-19

Company Type:
Trader
Location:
China
Qualification:
Main Products:

500

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Product Name: Nicotinamide Riboside Chloride (NR-Cl)

    CAS No.: 23111-00-4

    Alias: Nicotinamide Riboside, NRC

    Chemical Formula: C₁₁H₁₅ClN₂O₅

    Molecular Weight: 290.70

    Basic Properties


    • Appearance: White to off-white crystalline powder
    • Odor & Taste: Odorless, slightly bitter
    • Solubility: Freely soluble in water; soluble in DMSO
    • Purity: ≥98.0% (HPLC) (customizable to ≥99.0% for high-purity grade)

    Core Function & Mechanism


    As a bioactive form of vitamin B3 and a direct precursor of NAD⁺ (Nicotinamide Adenine Dinucleotide), NR-Cl is endogenously present in trace amounts in natural sources like milk, yeast, and brewer’s yeast. It acts as a substrate for nicotinamide riboside kinases (NRK1/2), facilitating its conversion to NMN and ultimately NAD⁺ in vivo.

    By boosting intracellular NAD⁺ levels, NR-Cl activates SIRT1 and SIRT3 deacetylases, supporting:

    • Mitochondrial function & energy metabolism
    • Cellular redox balance & antioxidant defense
    • DNA repair & anti-aging processes
    • Metabolic regulation & skeletal muscle health

    Key Applications


    1. Dietary Supplement Ingredient: A premium vitamin B3 source for NAD⁺ enhancement, widely used in anti-aging, metabolic health, and energy-boosting formulations.
    2. Biomedical Research: Tool compound for studying NAD⁺ metabolism, mitochondrial biogenesis, sirtuin biology, and age-related disease mechanisms.
    3. Functional Food & Cosmeceuticals: Incorporated into nutraceuticals and skincare for cellular anti-aging and skin barrier support.

    Storage & Handling


    • Storage Conditions: Store at -20°C in a dry, airtight container; protect from light and repeated freeze-thaw cycles.
    • Transport: Shipped on ice packs to maintain stability.
    • Shelf Life: 3 years when properly stored (-20°C, dry).

    Specifications (Standard Grade




    Parameter Specification Test Method
    Assay (HPLC) ≥98.0% HPLC
    Loss on Drying ≤1.0% Gravimetry
    Residue on Ignition ≤0.1% Gravimetry
    Heavy Metals ≤10 ppm ICP-MS
    Microbial Limit Complies with food safety standards Plate count

    Customization Options


    • Purity grades: 98.0% / 99.0% / 99.9%
    • Packaging sizes: 1g, 5g, 25g, 1kg, 5kg, 25kg (aluminum foil bags, cardboard drums)
    • Custom formulations: Coated NR, NR complex blends, and bulk raw materials for OEM/ODM projects

    Advantages


    • High Bioavailability: Superior absorption compared to conventional niacin/nicotinamide
    • NAD⁺ Precursor: Directly supports cellular energy production
    • Safe & Well-Tolerated: Suitable for long-term supplementation in healthy adults
    • Stable Form: Crystalline powder with long shelf life and easy handling

    Compliance


    Complies with international food safety and quality standards (FCC, EP, USP). Suitable for use in dietary supplements and functional food products worldwide.

    Certificates

    Basic Info
    Product Name:

    Nicotinamide riboside chloride

    Other Name:

    Nicotinamide riboside chloride;Nicotinamide Riboside.Cl;Nicotimide riboside chloride;Pyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, chloride (1:1);3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride;3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium chloride;3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride;Nicotinamide Riboside Chloride(NRC)

    CAS No.:

    23111-00-4

    Molecular Formula:

    C11H15ClN2O5

    InChIKeys:

    YABIFCKURFRPPO-TUHHAUDNNA-N

    Molecular Weight:

    290.7

    EC Number:

    200-184-4

    Color/Form:

    White

    HScode:

    2938909090

    Categories:

    Other Chemical Drugs

    Characteristics
    Water Solubility:

    10mg/mL, clear, colorless

    Critical Temperature & Pressure:

    under inert gas (nitrogen or Argon) at 2-8°C

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    500

    Location:

    NO.2 High Tech Road ,Xi'an,China

    Year of Establishment:

    2025

    Puremake Chem is an innovative life sciences supplements, custom synthesis and manufacturing services company. We are FDA registered manufacturer securing human health with consistent quality, sustainable growth. We manufacture and source a vast range of nutrition supplements, pharmaceutical products, and take pride in delivering them while others cannot. We are experts in both small molecules and biological raw materials. We provide a full range of products and services to support life science research and development, with around a hundred of complex manufacturing service projects. 

    Our R&D resources and production facilities, analytical instruments are modern and versatile, allowing us to produce chemicals on the milligram to ton scale, and at ISO 9001 and GMP.

    With chemistry & biology specialties and manufacturing services from the first idea to the finished product, from route scouting to GMP or ton scale production.  

    As a professional supplier and manufacturer of pharmaceutical chemicals and plant active ingredients, our products are mainly used in medicine, health supplement, cosmetics and other fields.







    Production  status

    Our production factory the floor area have of 12,000 square meters, and annual production capacity is more than several hundreds tons. Our company carries on complete quality management with quality manual under GMP regulation. Many products were approved by FDA, HACCP, KOSHER. Strict quality control is performed in every process from material sourcing, processing and analysis to packaging. We export products to North America, Europe, Southeast Asia, Oceania and etc. Our products gain wide praises at home and abroad.




    We warmly welcome customers from at home and abroad to establish cooperation and create a bright future with us together. And leading the way to make health industries heathier, help more people healthy and happy…


    Why Choose Us

    1. 10 + years specialized in health products field.

    2. GMP/ISO certificated factories and stable supply chain.

    3. Quality first, strictly control before shipments.

    4. Custom synthesis by more than 20 professional chemists.

    5. Small order,free sample and one step service available.

    6. Rapid delivery, 1-6 business days from China warehouse.

    7. Support 7 days refund money in case delay shipment.

    8. Assessment conducted by Bureau Veritas at 2018.


  • Inquiry History
    5 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Nicotinamide riboside chloride 98% NR 23111-00-4

    5 MT Jun 22, 2024
    Pakistan

    Wholesale Nicotinamide Riboside Chloride Powder 99% Powder Evergreen EGC-Nicotinamide Riboside Chloride CAS 23111-00-4

    50 KG Oct 17, 2023
    United States

    nicotinamide riboside chloride

    1 KG Feb 27, 2024
    Philippines

    NRcl

    1 KG Mar 1, 2026
    United States

    β-Nicotinamide Riboside Chloride

    1 KG Nov 22, 2024
    Post an enquiry for this product
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