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High Quality 99% Chlorpheniramine Maleate Powder CAS 113-92-8

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CAS No.:

113-92-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

HNB

Packaging:

25kg Cardboard Drum

Sample Available:

Yes

Price valid (until):

2026-04-13

Contact Supplier

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HNB Biotech

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

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Product Description
Seller Information
Inquiry History

Description

Product Description

Chlorpheniramine maleate, White crystalline powder. Melting point of 131-135 ºC. Soluble in water, chloroform, slightly soluble in ether, odorless, bitter taste.

Application

Chlorpheniramine maleate has more antihistamine effect than phenhydramine and promethazine. Used for urticaria, vasodilatory rhinitis, cold, asthma, rhinitis, contact dermatitis, also used for allergy, insect bite and motion sickness caused by medicine and food.

Use 1ethanol
Used as an anti-allergy drug
Use 2
Antihistamines. Similar to Cloromitone, bromphenyramide is also an antihistamine. Bromphenyramide is also produced in a similar way to cloromitone.
Use 3
The antihistamine effect of the product is more than diphenhydramine and promethazine, the dosage is small, the side effect is light. It is used for urticaria, vasodilator rhinitis, cold, asthma, rhinitis, contact dermatitis, and allergy caused by drugs and food, insect bites and motion sickness.

Items	Specifications
Name	Chlorpheniramine maleate
CAS	113-92-8
Molecular formula	C20H23ClN2O4
Density	390.861

About Us

Xian Harmonious Natural Bio- Technology Co., Ltd was founded in 2017, and located in Xian International Logistics Industrial Zone, Xian City. Shaanxi Province, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales deparments over 20 people and sell our products allover the word. We also have strong professional research and development team talented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
HNB mainly engaged in export of products incuding,without limitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acids minerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond and Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
Passion to innovate, Power to deliver !

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FAQ

Q1 Can i get some samples?

A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2 How to start orders or make payments?

A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information.

Payment by T/T,or Paypal or Escrow(Alibaba).

Q3 How to confirm the Product Quality before placing orders?

A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier

to us and take the samples. You can send us your product specifications and requests,we will manufacture

the products according to your requests.

Q4 What’s your MOQ?

A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge

is 100% paid.

Q5 How about delivery leadtime?

A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6 Is there a discount?

A6 Different quantity has different discount.

Q7 How do you treat quality complaint?

A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem

caused by us, we will send you free goods for replacement or refund your loss.

Q8 How to contact us ?

A8 You can choose your interested products and send inquiry to us.

ECHEMI Editorial Reference

Chlorpheniramine maleate is an histamine H1 receptor antagonist with IC50 of 12 nM.Target: Histamine H1 ReceptorChlorpheniramine inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 μM [1]. Chlorpheniramine displaces of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cells with IC50 of 66 nM. Chlorpheniramine displays antimalarial a
Chlorpheniramine maleate appears as odorless white crystalline solid or white powder with a bitter taste. pH (2% aqueous solution) 5. pH (1% aqueous solution) 4-5. (NTP, 1992)|Solid
Chlorpheniramine maleate appears as odorless white crystalline solid or white powder with a bitter taste. pH (2% aqueous solution) 5. pH (1% aqueous solution) 4-5. (NTP, 1992)|Chlorphenamine is a tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma. It has a role as a H1-receptor antagonist, an antipruritic drug, a histamine antagonist, a serotonin uptake inhibitor, an antidepressant and an anti-allergic agent. It is a tertiary amino compound, a member of monochlorobenzenes and a member of pyridines.|A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.|Brompheniramine and chlorpheniramine maleate are first generation antihistamines that are widely used to treat symptoms of allergic rhinitis and the common cold. Clinically apparent liver injury from brompheniramine or chlorpheniramine must be exceeding rare, if it occurs at all.|A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.

Certificates

Basic Info

Product Name:

Chlorpheniramine maleate

Other Name:

2-Pyridinepropanamine,γ-(4-chlorophenyl)-N,N-dimethyl-,(2Z)-2-butenedioate (1:1);Pyridine,2-[p-chloro-α-[2-(dimethylamino)ethyl]benzyl]-,maleate (1:1);2-Pyridinepropanamine,γ-(4-chlorophenyl)-N,N-dimethyl-,(Z)-2-butenedioate (1:1);1-p-Chlorophenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate;Histadur dura-tabs;Ibioton;1-Parachlorophenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate;Piriex;Synistamin;Teldrin;Chlorpheniramine maleate;Piriton;Chlor-Trimeton;Chloroprophenpyridamine maleate;Chlor-Tripolon;Chlorprophenpyridamine maleate;Carbinoxamide maleate;Neorestamin;Allergin;Chlorphenamine maleate;Puermin;dl-Chlorpheniramine maleate;(±)-Chlorpheniramine maleate;Chlorophenamine;Cloropiril;Allergisan;Histaspan;Antagonate;C-Meton;Chlorphenamine hydrogen maleate;Pyridamal 100;Histadur;Lorphen;Pirafene;Anallerge 4;Calimal;Niramine;Iramine;Histamil;Chlorphenamine;7054-11-7

CAS No.:

113-92-8

Molecular Formula:

C16H19ClN2.C4H4O4

InChIKeys:

InChIKey=DBAKFASWICGISY-BTJKTKAUSA-N

Molecular Weight:

390.86

Exact Mass:

390.134644

EC Number:

205-054-0

DSSTox ID:

DTXSID0022804

Color/Form:

OILY LIQUID

ATC Code:

R06AB54|R - Respiratory system

HScode:

2933399090

Categories:

Other Chemical Drugs

Characteristics

PSA:

90.7

XLogP3:

3.53040

Appearance:

Chlorpheniramine maleate appears as odorless white crystalline solid or white powder with a bitter taste. pH (2% aqueous solution) 5. pH (1% aqueous solution) 4-5. (NTP, 1992)

Density:

1.1±0.1 g/cm3

Melting Point:

130-135 °C

Boiling Point:

579.3°C at 760 mmHg

Flash Point:

9℃

Refractive Index:

1.565

Water Solubility:

H2O: 1-5 g/100 mL at 21 ºC

Storage Conditions:

-20°C Freezer

Vapor Pressure:

2.9E-14mmHg at 25°C

Dissociation Constants:

9.13 (at 25 °C)

Collision Cross Section:

164.5 Å² [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]

Experimental Properties:

WHITE CRYSTALLINE POWDER; ODORLESS; SOLN ARE ACID TO LITMUS HAVING PH BETWEEN 4 & 5; MP:BETWEEN 130 °C & 135 °C; SLIGHTLY SOL IN ETHER & BENZENE /MALEATE/

Air and Water Reactions:

Water soluble.

Reactive Group:

Hydrocarbons, Aliphatic Unsaturated

Reactivity Profile:

An acidic salt of an organic amine. Materials in this group are generally soluble in water, though some also may react with water. The resulting solutions contain moderate concentrations of hydrogen ions and have pHs of less than 7.0. Compounds in this group react as weak acids to neutralize bases. These neutralizations generate heat, but less than is generated by neutralization of inorganic acids, inorganic oxoacids, or carboxylic acids. Many of these compounds catalyze organic reactions.

See More Chlorpheniramine maleate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Chlorpheniramine maleate Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2017

Company Certificates
- ISO
- ISO
Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

leading researcher and one of the biggest manufacturer in high technology API area.

There are 8 experts in our research team. We insist in innovation and produce high quality

products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales departments over 20 people and sell our products all over the world.

We also have strong professional research and development team, talented personnel and

completely equipped laboratory for the quality controlling. Various Detection Device is

equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

extract, feed and food additives.

Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

from both home and abroad.

Passion to innovate, Power to deliver !

Inquiry History

20 Inquiries

Country	Product	Purchase Quantity	Date Posted
Indonesia	High Purity 99% Chlorpheniramine Maleate Powder CAS 113-92-8	100 G	Feb 20, 2024
Nigeria	Chloropheniramine	200 G	Jun 26, 2025
Egypt	Chlorpheniramine Maleate	200 G	Jan 29, 2026
Pakistan	Chlorpheniramine Maleate	10000 KG	Jun 5, 2025
India	Chlorpheniramine maleate 98 %	5 MT	Apr 11, 2024
Myanmar	Chlorpheniramine maleate	1 KG	Jan 12, 2024
Bangladesh	Chlorphenamine maleate API BP 99% powder.	800 KG	Aug 18, 2026
United States	Chlorpheniramine maleate	1 KG	Apr 15, 2026
Ecuador	CLORFENAMINA MALEATO	1 KG	Nov 19, 2024
Egypt	chlorphenamine maleate	1 KG	Jul 9, 2024
Thailand	High Purity 99% Chlorpheniramine Maleate Powder	1 KG	Mar 7, 2024
Bangladesh	Chlorpheniramine Maleate	1000 KG	Feb 28, 2024
Paraguay	Sodium lauryl ether sulphate	4000 KG	Feb 25, 2026
Paraguay	Fenthion	400 KG	Mar 13, 2026
Paraguay	N-Methil-2-pyrrolidone	1000 KG	Feb 25, 2026
Paraguay	Benzidamine hidrochloride	300 KG	Feb 25, 2026
Paraguay	Cypermethrin	3000 KG	Feb 25, 2026
Paraguay	Penicillin G sodium	2200 BOU	Mar 24, 2026
Paraguay	Cypermethrin	300 KG	Mar 24, 2026
Paraguay	Eprinomectina	3 KG	Apr 23, 2026

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High Quality 99% Chlorpheniramine Maleate Powder CAS 113-92-8

Product Description

Seller Information