99% purity Cagrilintide Peptides CAS 1415456-99-3 raw materials Weight Loss factory selling

     Cagrilintide (commonly translated as "Cagrilinide") is a long-acting analog of amylin that is currently in clinical research. It was developed by the Danish pharmaceutical company Novo Nordisk and is mainly used for the treatment of obesity and type 2 diabetes.

     Calglucin peptide is a non-selective amylin receptor (AMYR) and calcitonin gene-related peptide (CTR) receptor. It enhances satiety and reduces food intake by mimicking the human endocrine-like amylin similar to insulin, thereby achieving the effect of weight loss. Its mechanism of action is different from GLP-1 receptors (such as semaglutide), providing a new approach for the treatment of obesity.
As a long-acting lipophilic amylin analogue, it achieves weight loss, blood sugar control, and metabolic optimization through multi-target synergy, and is an important supplement to GLP-1 drugs.

     Storage conditions: Store at -20℃ in a dark and sealed container.

     Main function
   1.Strong weight loss effect: 2.4mg of the drug once a week, an average weight loss of 11.8% over 68 weeks. Compared with the 2.4mg combination formulation of semaglutide (CagriSema), the average weight loss over 68 weeks was 20.4%, and 40.4% of patients achieved a weight loss of ≥25%.
   2. Collaborative glucose control: Inhibiting glucagon, improving insulin sensitivity. When combined with semaglutide, it can reduce HbA1c levels by 1.91% in patients with type 2 diabetes.
   3. Multiple mechanisms: Activates the brainstem satiety pathway, delays gastric emptying, reduces fat tissue, and has a low incidence of gastrointestinal adverse reactions and good tolerance.

     Mechanism of action
   1. Simulates the natural secretion of amylin after a meal, activating the dual pathways of amylin receptors (AMYRs) and calcitonin receptors (CTR).

   2. Acts on the hypothalamus and the solitary nucleus of the brainstem, enhancing the feeling of fullness, suppressing appetite, and prolonging the interval between meals.
   3. Delay gastric emptying, reduce gastric acid secretion, prolong the retention time of nutrients, and lower calorie intake.
   4. Inhibit the secretion of glucagon, reduce the output of liver glycogen, and improve fluctuations in blood sugar levels.

    Hongbai Technology Co., Ltd. is  a branch of Changsha Dolo Technology Co., Ltd.，which is a pioneering force in the biotechnology sector.

    At the core of our operations is the unwavering commitment to our guiding principles : "Quality First, Service Supreme."Our mission is to spearhead advancements in biotechnology by consistently upholding the highest standards of quality and service. Through innovation and excellence, we aim to contribute to the betterment of global health and well-being.

   Our primary focus encompasses a range of products , including weight loss peptideses, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Tirzepatide, Retatrutide, and others.Provides reliable and timely custom manufacturing services for API following stringent quality system and close communication with the Clients.We have professional sales team , focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market, our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.

   With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers .

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