Fmoc-D-Phe(2-Me)-OH | CAS 352351-63-4

Fmoc-D-Phe(2-Me)-OH is an unnatural amino acid derivative of phenylalanine, which can be used in the synthesis of peptides and is often used in scientific research.

Unnatural amino acids (ncAAs) play a wide and important role in the application of peptides, which are mainly reflected in structural optimization, functional enhancement, improvement of pharmaceutical properties and construction of new materials. Their core applications can be summarized as follows:

Improve the pharmaceutical properties of peptide 

Enhance stability: resist protease/peptidase degradation and prolong half-life.

Improve pharmacokinetics: improve water solubility, reduce immunogenicity and optimize biological distribution.

Typical application: peptide receptor agonists, such as smegrupeptide and liraglutide, all contain unnatural amino acid modifications to prolong the in vivo action time.

A series of unnatural amino acids have been used for protein modification in bacteria, yeast and mammalian cells with high accuracy and efficiency. Most of them are derivatives of 20 natural amino acids.

Omizzur biotech is committed to the synthesis of various amino acid derivatives and peptides. At present, there are more than 1,000 kinds of amino acid products and more than 200 kinds of peptide products available in stock. In addition, Omizzur also provides customized synthesis of peptides, which can be used for scientific research. A large order will have discount.