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Upadacitinib White Crystalline Powder CAS No 1310726-60-3 Upadacitinib

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CAS No.:

1310726-60-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

Packaging:

25kg drum

Sample Available:

Yes

Price valid (until):

2026-04-24

Contact Supplier

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HNB Biotech

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

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Product Details
Seller Information
Inquiry History

Description

Product Detail

whasapp：+8615202961574
Email:gary@xahnb.com

Items	Standard		Test Results

Identification	A.H-NMR:Comply with the structure		Complies
	B.LC-MS:Comply with the structure		Complies
	C.The IR spectrum of sample should be identical with that of reference standard.		Complies
	D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.		Complies
Loss on drying %	≤2.0		0.19
Heavy metals ppm	≤10		<10
Moisture %	≤1.0		0.1
Sulphated ash %	≤0.5 determined on 1.0 g.		0.009
Residue on ignition %	≤0.1		0.03
Related Substances %	Unspecified impurities: for each impurity	≤0.10	<0.10
Related Substances %	Total Impurity	≤0.5	0.18
Purity %	≥99.0		99.7
Assay %	99.0 ~101.0 (anhydrous substance).		99.8
Storage	Preserve in well-closed, light-resistant and airtight containers.		Complies

Xran Harmonious Natural Bio- Technology Co., Ltd was founded in 2017, and located in Xlan International Logistics Industrial Zone, Xran City. ShaanxtProvince, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainlessextraction equipment.

We have 2 sales deparments over 20 people and sellour products allover the word. We also have strong professional research and developmentteamtalented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on
HNB mainly engaged in export of products incuding,wthoutlimitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acidsminerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond andAchieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
Passion to innovate, Power to deliver !

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Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T,or Paypal or Escrow(Alibaba).
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8 How to contact us
A8 You can chat with us by Trademanager,MSN&Skype Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly or send Email to us., you will get our reply.

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ECHEMI Editorial Reference

Upadacitinib is a JAK1 inhibitor (IC50= 47 nM). It is selective for JAK1 over JAK3 and tyrosine kinase 2 (Tyk2; IC50s = 2,304 and 4,690 nM, respectively), as well as a panel of 83 additional kinases at 1 μM, but does inhibit JAK2, Rho-associated kinase I (ROCK1), and ROCK2 (IC50s = 120, 920, and 430 nM, respectively). Upadacitinib decreases cytokine-induced STAT phosphorylation in a variety of human cells with IC50values ranging from 1.6 to 649 nM. It reducesM. tuberculosis-induced paw swelling and bone erosion in a rat model of arthritis when administered at doses of 1, 3, and 10 mg/kg twice per day for 17 days. Formulations containing upadacitinib have been used in the treatment of rheumatoid arthritis.
Upadacitinib was discovered by AbbVie scientists, RINVOQ is a JAK inhibitor that is being studied in several immune-mediated inflammatory diseases. In human leukocyte cellular assays, RINVOQ inhibited cytokine-induced STAT phosphorylation mediated by JAK1 and JAK1/JAK3 more potently than JAK2/JAK2 mediated STAT phosphorylation. Upadacitinib (RINVOQ) received FDA approval in 2019 for the treatment of moderate to severe RA.

Certificates

Basic Info

Product Name:

Upadacitinib

Other Name:

Upadacitinib;Upadacitinib (ABT-494);ABT-494 (Upadacitinib);Upadacitinib (Rinvoq);ABT-494; ABT494; ABT 494;CS-2730;(3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, Upadacitinib;1-Pyrrolidinecarboxamide, 3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-, (3S,4R)-

CAS No.:

1310726-60-3

Molecular Formula:

C17H19F3N6O

InChIKeys:

WYQFJHHDOKWSHR-MNOVXSKESA-N

Molecular Weight:

380.37

Exact Mass:

380.37

EC Number:

213-161-9

Color/Form:

White to off-white

Categories:

Antidementia Agents

Characteristics

PSA:

78.32

XLogP3:

3.2367

Density:

1.56±0.1 g/cm3(Predicted)

PKA:

11.89±0.60(Predicted)

Critical Temperature & Pressure:

Store at -20°C

See More Upadacitinib Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Upadacitinib Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2017

Company Certificates
- ISO
- ISO
Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

leading researcher and one of the biggest manufacturer in high technology API area.

There are 8 experts in our research team. We insist in innovation and produce high quality

products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales departments over 20 people and sell our products all over the world.

We also have strong professional research and development team, talented personnel and

completely equipped laboratory for the quality controlling. Various Detection Device is

equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

extract, feed and food additives.

Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

from both home and abroad.

Passion to innovate, Power to deliver !

Inquiry History

13 Inquiries

Country	Product	Purchase Quantity	Date Posted
Hongkong, China	Upadacitinib	50 MG	Apr 7, 2026
Pakistan	UPADACITINIB	0.51 KG	Feb 25, 2026
India	Upadacitinib	100 G	Nov 24, 2025
Pakistan	Upadacitinib	1 KG	Feb 17, 2025
India	Upadacitinib	1000.00 KG	Feb 13, 2025
India	Upadacitinib	30.00 KG	May 20, 2024
India	URSODEOXYCHOLIC ACID	10.00 KG	Mar 6, 2024
India	Upadacitinib	10.00 KG	Mar 6, 2024
India	Acarbose	10.00 KG	Mar 6, 2024
India	Ripretinib	10.00 KG	Mar 6, 2024
India	Upadacitinib - ABT- 494	5.00 KG	Jan 19, 2024
India	Upadacitinib	5 KG	Jan 17, 2024
India	Upadacitinib	5 KG	Nov 29, 2023

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Upadacitinib White Crystalline Powder CAS No 1310726-60-3 Upadacitinib

Product Details

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