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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Bedaquiline for Sale > High Quality Bedaquiline CAS 843663-66-1 Raw Materials White Powder
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High Quality Bedaquiline CAS 843663-66-1 Raw Materials White Powder

Unit Price:

$10.2-11.22/G FOB

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CAS No.:

843663-66-1

Grade:

Chemical Grade

Content:

99%

Port:

shanghai

Brand:

Wuhan pnq

Packaging:

Aluminum foil bag

Price valid (until):

2026-06-25

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Apigenin,PQQ,NMNH

  • Product Description

  • Seller Information

  • History Price

  • Description
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    Q1: What's your MOQ?
    A:It depends on different products,we can accept sample order or provide free sample for your test.
    Q2:How about delivery leadtime?
    A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
    Q3: Is there a discount?
    A:Different quantity has different discount.
    Q4:How to start orders or make payments?
    A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T or Bitcoin.
    Q5: How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
    Q6:We don't know you at all, how can we trust you?
    A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
    Q7:Do you test all your goods before delivery?
    A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.

    Introduction: 

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    Description

    Name

    Bedaquiline

    CAS number

    843663-66-1

    EINECS number

    1308068-626-2

    Synonym

    TMC-207;6-Bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinolineethanol;

    Description

    Bedaquiline is a novel diarylquinoline based anti tuberculosis drug that inhibits the activity of the ATP synthase proton pump in Mycobacterium tuberculosis, thereby affecting its ATP synthesis and exerting antibacterial and bactericidal effects.



    Molecular Formula

    C32H31BrN2O2

    Molecular Weight

    555.5g/mol

    Appearance

    White powder

    Quality Standard

    In-house

    Assay

    99.31%

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    More Info

    Bedaquiline is a diarylquinoline antimycobacterial agent used to treat multi-drug resistant tuberculosis (MDR-TB) by inhibiting mycobacterial ATP synthase. It is a critical, often life-saving component of 6-month, short-course regimens, providing a faster, more effective treatment option for drug-resistant TB compared to older methods.


    How it works

    Bedaquiline has equal bactericidal activity against both sensitive and resistant strains of Mycobacterium tuberculosis, and also has good bactericidal effect on dormant bacteria.





    Basic Info
    Product Name:

    Bedaquiline

    Other Name:

    3-Quinolineethanol,6-bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-,(αS,βR)-;(αS,βR)-6-Bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol;R 207910;TMC 207;Bedaquiline;Sirturo

    CAS No.:

    843663-66-1

    Molecular Formula:

    C32H31BrN2O2

    InChIKeys:

    InChIKey=QUIJNHUBAXPXFS-XLJNKUFUSA-N

    Molecular Weight:

    525.487

    Exact Mass:

    555.50

    EC Number:

    1308068-626-2

    Color/Form:

    White solid

    Characteristics
    PSA:

    45.6

    XLogP3:

    log Kow = 7.74 (est)

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    104 °C

    Flash Point:

    378.8±32.9 °C

    Refractive Index:

    1.666

    Water Solubility:

    Insoluble

    Storage Conditions:

    Tablets dispensed outside the original container should be stored in a tight light-resistant container with an expiration date not to exceed 3 months. Store at 25 °C (77 °F); excursions permitted to 15-30 °C (59-86 °F).

    Vapor Pressure:

    3.66X10-16 mm Hg at 25 °C (est)

    Specific rotation:

    Specific optical rotation: -166.98 deg at 20 °C/D (c = 0.505 in dimethyl formamide)

    Henrys Law Constant:

    Henry's Law constant = 4.41X10-18 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa1 = 1.57 (imine); pKa2 = 8.91 (amine); pKa3 = 13.61 (hydroxyl) (est)

    Experimental Properties:

    White to almost white powder; practically insoluble in aqueous media/Bedaquiline fumarate/|White solid /Bedaquiline fumarate/

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Specific target organ toxicity – repeated exposure, Category 2

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H373 May cause damage to organs through prolonged or repeated exposure

    H400 Very toxic to aquatic life

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P273 Avoid release to the environment.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Apigenin,PQQ,NMNH

    Location:

    Room 1006, Building C6, Economic Development Wanda, Caidian District, Wuhan City, Hubei Province

    Payment Terms:

    100% TT in advance

    Average lead Time:

    30

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2021

    Wuhan PNQ trade located in Wuhan, China, is an innovative natural products manufacturer and supplier that offers raw powders as dietary ingredients, food and beverage additives, sports nutrition supplements.

  • Weekly Price

    The chart shows the price trend of the product in the past 12 months.

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