High Quality CAS 111470-99-6 Amlodipine Besylate Powder

Amlodipine besylate, commonly known by the brand name Norvasc, is a long-acting calcium channel blocker used to treat hypertension (high blood pressure) and angina (chest pain). It works by relaxing the arteries and increasing their diameter, a process known as vasodilation.

Mechanism of Action

Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. It primarily affects vascular smooth muscle cells, causing vasodilation and reducing peripheral vascular resistance, which lowers blood pressure. Amlodipine can also prevent excessive constriction in the coronary arteries.
The mechanisms by which amlodipine relieves angina are:
Stable angina: Amlodipine reduces the total peripheral resistance (afterload) against which the heart works, reducing myocardial oxygen demand.
Variant angina: Amlodipine blocks spasm of the coronary arteries and restores blood flow.

Applications

Amlodipine besylate is primarily used to treat:
Hypertension (high blood pressure)
Chronic stable angina (chest pain)
Vasospastic angina (Prinzmetal's angina)
It can be used alone or in combination with other medications to manage these conditions. A fixed-dose combination of amlodipine and perindopril, an angiotensin converting enzyme inhibitor, is also available.

Xian Harmonious Natural Bio- Technology Co., Ltd was founded in 2017, and located in Xian International Logistics Industrial Zone, Xian City. Shaanxi Province, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales deparments over 20 people and sell our products allover the word. We also have strong professional research and development team talented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
HNB mainly engaged in export of products incuding,without limitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acids minerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond and Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
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Q1 Can i get some samples?

A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2 How to start orders or make payments?

A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information.

Payment by T/T,or Paypal or Escrow(Alibaba).

Q3 How to confirm the Product Quality before placing orders?

A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier

to us and take the samples. You can send us your product specifications and requests,we will manufacture

the products according to your requests.

Q4 What’s your MOQ?

A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge

is 100% paid.

Q5 How about delivery leadtime?

A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6 Is there a discount?

A6 Different quantity has different discount.

Q7 How do you treat quality complaint?

A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem

caused by us, we will send you free goods for replacement or refund your loss.

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