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High Purity Busulfan CAS 55-98-1 99% Assay Raw Powder USP Standard

Name: High Purity Busulfan CAS 55-98-1 99% Assay Raw Powder USP Standard
Brand: Wuhan pnq
SKU: pr2603251178
Price: 10.2 USD
Availability: InStock

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Unit Price:

$10.2-11.22/G FOB

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CAS No.:

55-98-1

Grade:

Chemical Grade

Content:

99%

Port:

shanghai

Brand:

Wuhan pnq

Packaging:

Aluminum foil bag

Price valid (until):

2026-06-25

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Wuhan Pnq Int Trade Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Apigenin,PQQ,NMNH

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Seller Information
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Q1: What's your MOQ?

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Q2:How about delivery leadtime?

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

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Description

Name	Busulfan
CAS number	55-98-1
EINECS number	200-250-2
Synonym	BUSULFAN;tetramethylene bis(methanesulfonate);myleran;busulfex;busulphan;
Description	Busulfan is a cell cycle non-specific alkylating agent, belonging to the alkyl sulfonate type, with the chemical name 1,4-butanediol dimethyl sulfonate.
Structure	\
Molecular Formula	C6H14O6S2
Molecular Weight	246.3g/mol
Appearance	White powder
Quality Standard	In-house
Assay	99.79%
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

More Info

Busulfan is a potent chemotherapy drug classified as an alkylating agent. It primarily treats certain types of leukemia and is a crucial part of the conditioning regimen before a bone marrow or stem cell transplant.

Mechanism of action

Busulfan works by damaging the DNA of cancer cells, which prevents them from dividing and eventually leads to their death. This action makes it particularly effective at suppressing bone marrow activity (myelosuppression), making room for transplanted hematopoietic stem cells to grow.

Medical Uses

Palliative Treatment: In lower doses, it can be used for the palliative treatment of CML and other myeloproliferative disorders like polycythemia vera and essential thrombocythemia.

Basic Info

Product Name:

Busulfan

Other Name:

1,4-Butanediol,1,4-dimethanesulfonate;1,4-Butanediol,dimethanesulfonate;Methanesulfonic acid,tetramethylene ester;GT 41;NSC 750;CB 2041;1,4-Bis(methanesulfonoxy)butane;Busulphan;1,4-Dimethanesulfonoxybutane;1,4-Dimethylsulfonyloxybutane;Mablin;Mitostan;Myelosan;Myleran;Tetramethylene bis[methanesulfonate];Busulfan;Misulban;Mielosan;Mileran;Milecitan;Sulfabutin;1,4-Bis(methanesulfonyloxy)butane;Leucosulfan;Mylecytan;Mielucin;1,4-Butanediol dimesylate;Glyzophrol;Butane-1,4-diyl bis(methanesulfonate);1,4-Dibutanediol dimethanesulfonate;Busulfex;GT 2041;Myeloleukon;X 149;Sulphabutin;2041CB;AN 33501;Mielevcin;NCI C01592;Citosulfan;Busilvex;Myran;4-Methylsulfonyloxybutyl methanesulfonate

CAS No.:

55-98-1

Molecular Formula:

C6H14O6S2

InChIKeys:

InChIKey=COVZYZSDYWQREU-UHFFFAOYSA-N

Molecular Weight:

246.3

Exact Mass:

246.30

EC Number:

200-250-2

UNII:

G1LN9045DK

NSC Number:

755916|750

UN Number:

2811

DSSTox ID:

DTXSID3020910

NCI Thesaurus Code:

C321

Color/Form:

White needles|Crystals

ATC Code:

L01AB01|L - Antineoplastic and immunomodulating agents

HScode:

2942000000

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

104

XLogP3:

-0.5

Appearance:

Pale Brown Crystalline Powder

Density:

1.56 g/cm³

Melting Point:

114-118 °C

Boiling Point:

464ºC at 760 mmHg

Flash Point:

9℃

Refractive Index:

1.471

Water Solubility:

Decomposes in water

Storage Conditions:

Hygroscopic, Refrigerator, Under Inert Atmosphere

Vapor Pressure:

6.56X10-6 mm Hg at 25 deg C (est)

Toxicity:

Peritoneal-rat LD50: 22 mg/kg; oral-mouse LD50: 110 mg/kg

Flammability characteristics:

Thermal decomposition to emit toxic sulfur oxide fumes

Henrys Law Constant:

Henry's Law constant = 5.16X10-10 atm-cu m/mol at 25 °C (est)

Experimental Properties:

Hydroxyl radical reaction rate constant = 4.70X10-12 cu cm/molec-sec at 25 °C (est)

Air and Water Reactions:

This compound is an alkylating agent which hydrolyzes in water. (NTP, 1992).

Reactive Group:

Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

Reactivity Profile:

MYLERAN is an alkylating agent which hydrolyzes in water. (NTP, 1992). Strong reducers may yield hydrogen sulfide.

See More Busulfan Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Acute toxicity - Category 2, Dermal

Acute toxicity - Category 2, Inhalation

Carcinogenicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H310 Fatal in contact with skin H330 Fatal if inhaled H350 May cause cancer
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. P203 Obtain, read and follow all safety instructions before use.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Commercially available busulfan for injection concentrate should be stored in unopened ampules at 2-8 deg C. The manufacturer states that, when diluted as directed in 0.9% sodium chloride injection or 5% dextrose injection, busulfan solutions are stable for up to 8 hours when stored at room temperature (approximately 25 deg C), and the busulfan infusion must be completed during the 8-hour time period. Solutions of busulfan diluted in 0.9% sodium chloride injection also have been shown to be stable when refrigerated at 2-8 deg C for up to 12 hours, during which time the infusion must be completed.

See More Busulfan Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Apigenin,PQQ,NMNH

Location:
Room 1006, Building C6, Economic Development Wanda, Caidian District, Wuhan City, Hubei Province

Payment Terms:
100% TT in advance

Average lead Time:
30

Total Annual Revenue:
Less than $1 million

Total Employees:
5-10

Year of Establishment:
2021

Wuhan PNQ trade located in Wuhan, China, is an innovative natural products manufacturer and supplier that offers raw powders as dietary ingredients, food and beverage additives, sports nutrition supplements.
Weekly Price

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Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Taiwan, China	Busulfan	1 KG	Oct 10, 2024

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High Purity Busulfan CAS 55-98-1 99% Assay Raw Powder USP Standard

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