High Quality Lotilaner CAS 1369852-71-0 Powder

Lotilaner More Info

Lotilaner is a veterinary antiparasitic medication primarily used for the treatment and prevention of flea and tick infestations in dogs. It belongs to the class of isoxazolines and is known for its efficacy against various ectoparasites. Here are the key details about Lotilaner:

Mechanism of Action

Lotilaner works by inhibiting the action of specific neurotransmitter receptors in parasites. As a potent antagonist of the glutamate-gated chloride channels (GluCl) and GABA-gated chloride channels (GABA), Lotilaner disrupts the nervous system function in fleas and ticks. This leads to an increase in neural excitation, resulting in paralysis and subsequent death of these parasites.

Indications

Lotilaner is indicated for:

Flea Control: Effective against adult fleas, providing rapid relief from infestations.

Tick Control: It is also effective against various tick species, including those that may transmit diseases to dogs.

Acaricide: Provides control of certain mite infestations as well.

Dosage and Administration

Lotilaner is typically administered orally as a flavored chewable tablet. The dosage will depend on the weight of the animal, and it is generally given once a month. It is important for pet owners to adhere to their veterinarian's recommendations regarding dosing and administration to ensure optimal efficacy.