ISO Factory Supply CAS 53179-13-8 Pirfenidone Pharmaceutical raw powder Pirfenidone
TDS
53179-13-8
Pharmaceutical Grade
99%
Shanghai
HNB
1kg/bag, 25kg/drum or as request
2026-04-26
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferencePirfenidone is a drug used for the treatment of idiopathic pulmonary fibrosis. It inhibits FGFR, EGFR, PDGFR, TGF-β, thereby slowing tumor cell proliferation.
Pirfenidone is a pyridone that is 2-pyridone substituted at positions 1 and 5 by phenyl and methyl groups respectively. An anti-inflammatory drug used for the treatment of idiopathic pulmonary fibrosis. It has a role as a non-narcotic analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.|Pirfenidone is an orally active small molecule drug that may inhibit collagen synthesis, down regulate production of multiple cytokines and block fibroblast proliferation and stimulation in response to cytokines. Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver. It is being investigated by InterMune.|Pirfenidone is a Pyridone.|Pirfenidone is an orally available pyridinone derivative that inhibits collagen formation and is used to treat idiopathic pulmonary fibrosis. Elevations in serum enzyme levels during pirfenidone therapy are not uncommon, but it has yet to be implicated in cases of clinically apparent liver injury with jaundice.|Pirfenidone is an orally active synthetic antifibrotic agent structurally similar to pyridine 2,4-dicarboxylate. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis. (NCI04)CertificatesBasic Info-
Product Name:
Pirfenidone
Other Name:2(1H)-Pyridinone,5-methyl-1-phenyl-;5-Methyl-1-phenyl-2(1H)-pyridinone;Pirfenidone;5-Methyl-1-phenyl-2(1H)-pyridone;AMR 69;5-Methyl-1-phenyl-1H-pyridin-2-one;Deskar;Pirespa;Esbriet;RG6062;RG 6062;RG-6062;835632-50-3
CAS No.:53179-13-8
Molecular Formula:C12H11NO
InChIKeys:InChIKey=ISWRGOKTTBVCFA-UHFFFAOYSA-N
Molecular Weight:185.22200
Exact Mass:185.22
UNII:D7NLD2JX7U
NSC Number:748456
DSSTox ID:DTXSID4045183
NCI Thesaurus Code:C2635
Color/Form:White solid from hot water
ATC Code:L04AX05|L - Antineoplastic and immunomodulating agents
HScode:2933399090
Categories:
Characteristics-
PSA:
22.00000
XLogP3:1.9
Appearance:Off-White Solid
Density:1.137 g/cm3
Melting Point:96-97ºC
Boiling Point:329.1ºC at 760 mmHg
Flash Point:152.7ºC
Refractive Index:1.592
Water Solubility:DMSO: ≥10 mg/mL, soluble ;Solubule in methanol
Storage Conditions:Store at RT
Vapor Pressure:3.68X10-5 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 9.16X10-8 at 25 °C (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 5.12X10-12 cu cm/molecule-sec at 25 °C (est)|Ozone radical reaction rate constant = 5.26X10-17 cu cm/molecule-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China
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Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2017
Company Certificates-
![HNB BiotechISO]( "ISO")
ISO
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![HNB BiotechISO]( "ISO")
ISO
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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