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SLU-PP-332 is a pan-agonist of the estrogen receptor-related receptors (EC50’s cell-based cotransfection/reporter assay: ERRα = 98 nM, ERRß = 230 nM, ERRγ = 430 nM) with highest potency for ERRα. Developed to mimic the physiological benefits of exercise, it has shown promise in alleviating conditions such as obesity and metabolic syndrome in preclinical studies. This compound activates all three ERR isoforms, with a slightly higher potency towards ERRα, making it a significant candidate for therapeutic applications in metabolic diseases.
Mechanism of Action
SLU-PP-332 functions by activating ERRs, which are nuclear receptors involved in regulating energy metabolism. Upon administration, it induces a metabolic shift towards increased fatty acid oxidation and energy expenditure, similar to the physiological adaptations observed during exercise. Specifically, studies have shown that SLU-PP-332 leads to:
1. Increased Fatty Acid Oxidation: A 25% increase compared to control groups.
2. Decreased Carbohydrate Utilization: Indicating a preference for lipid metabolism.
3. Enhanced Glucose Uptake: Notably in muscle tissues after prolonged treatment
Applications
SLU-PP-332 has potential applications in:
1. Metabolic Syndrome Treatment: By reducing fat mass and improving insulin sensitivity.
2. Obesity Management: Demonstrating efficacy in mouse models for weight loss and metabolic health improvement.
3. Exercise Mimetic Research: Offering an alternative to physical exercise for those unable to engage in regular activity due to health constraints
Safety and Side Effects
While specific human clinical data on the safety profile of SLU-PP-332 are limited, preclinical studies indicate that it effectively reduces hepatic triglycerides without significant adverse effects noted in animal models. Further research is necessary to fully understand its safety profile and potential side effects in humans.
| Items | Specifications |
| Product Name | SLU PP |
| Purity | >99% |
| Appearance | White lyophilized powder |
| Package | 5mg ,10mgvials/box |
| Function | Weight Loss Anti-aging |
| Shelf Life | 2 years |
| Storage | Cool and Dry Place |
Function
1. Weight Loss
SLU-PP-332 induces weight loss by mimicking the metabolic effects of exercise. The compound activates key pathways involved in fat oxidation and energy expenditure, leading to increased calorie burning even at rest. This product effect helps users achieve a caloric deficit, facilitating fat loss while preserving lean muscle mass. Importantly, SLU-PP-332 does not suppress appetite or alter eating habits, making it a safe and sustainable option for weight management .
2. Endurance Enhancement
By enhancing mitochondrial function and optimizing energy production, SLU-PP-332 significantly improves physical endurance. The compound increases the efficiency of ATP synthesis, providing muscles with a sustained energy supply during prolonged activity. This results in reduced fatigue and improved performance, allowing users to engage in physical activities for longer durations without feeling exhausted.
Hongbai Technology Co., Ltd. is a branch of Changsha Dolo Technology Co., Ltd.，which is a pioneering force in the biotechnology sector.
At the core of our operations is the unwavering commitment to our guiding principles : "Quality First, Service Supreme."Our mission is to spearhead advancements in biotechnology by consistently upholding the highest standards of quality and service. Through innovation and excellence, we aim to contribute to the betterment of global health and well-being.
Our primary focus encompasses a range of products , including weight loss peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Tirzepatide, Retatrutide, and others.Provides reliable and timely custom manufacturing services for API following stringent quality system and close communication with the Clients.We have professional sales team , focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market, our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers .
1.We have more than 10 years of experience in the field of chemical industry, the company's products are exported to more than 60 countries overseas, of which 80% are exported to Europe and America, 20% are exported to Southeast Asia, the Middle East, South Africa and other regions.
2.We have our own production plant and R & D center, to provide customers with technical support, product customization, free recipes and other whole industry chain services. Support full video inspection, testing, global delivery package.
3.We accept sample orders for testing, after purchasing products from our factory, we have a professional technical team and after-sales team to serve you and solve all your future problems. 100% quality assurance, 100% safe delivery.
Q1: Can I get a sample before placing an order?
A1: Yes, we can provide samples, you only need to pay the shipping fee and sample fee.
Q2: Why should you buy from us instead of other suppliers?
A2: Because we are a factory, we can provide lower prices and guaranteed quality. We have extensive experience in domestic and foreign trade and provide services in an honest, timely and efficient manner.
Q3: How to place an order for each product?
A3: Please send us an inquiry and let us know your requirements; we will send you a complete quotation including freight, confirm the order and send payment/deposit, we will arrange production or delivery of the goods after receiving the bank receipt.
Q4: Do you have stock?
A4: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
Welcome to be our distinguished customer,please do not hesitate to contact us!
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