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CAS 2381089-83-2 High Purity Retatrutide Peptides Weight LossTirzepatide Semaglutide factory price

Name: CAS 2381089-83-2 High Purity Retatrutide Peptides Weight LossTirzepatide Semaglutide factory price
Brand: zwxs
SKU: pr2603311269
Price: 100 USD
Availability: InStock

TDS 7503 Inquiries

Unit Price:

$100-110/MT FOB

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CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

guangzhou

Brand:

zwxs

Packaging:

10mg/vial,15mg/vial

Sample Available:

Yes

Price valid (until):

2026-12-25

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Jinan Zhiwenxinsheng Electric Technology Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

3 days

Qualification:

Main Products:

peptides

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Product Details
Seller Information
Inquiry History

Description

Product Detail

Name:Kate

Whatsapp:+86 18562300759

Email Address:zwxs2@zwxstech.com

Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

Name	Retatrutide
CAS RN	2381089-83-2
Solubility	Dissolved in dimethyl sulfoxide
Storage condition	-20°C
EINECS	200-001-8

Appearance: Powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Company profile

Jinan Zhiwen Technology Co., Ltd was established in 2020 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures.

With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical peptides and proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, functional peptides and protein products, etc.

Its core team is composed of technical experts in the fields of pharmaceutical engineering, fermentation engineering and protein engineering. The company has built a 3,300-square-meter recombinant drug research and development center in Shibei, Yuelu District, Changsha City. It has a complete pharmaceutical engineering, preparation and quality research system and talent team, and has built a GMP workshop to meet the international market API supply and CDMO services.

At present, our company has realized the industrialization of a variety of biosynthetic peptide products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.

Why choose us

Our company has independent factories, mass production of pharmaceutical intermediates, organic intermediates and other raw materials, widely used in medicine, health care products, cosmetics, nutritional supplements, food additives and other fields.

Our company adheres to the business philosophy of integrity and cooperation. scientific innovation and service first.With absolute quality assurance as the purpose and perfect service system as the basis, our company provides efficient and satisfactory consulting services, sincerely welcomes your business inquiries,and looks forward to working with you to create a new future.

Key Products:
Our primary focus encompasses a range of products, including weight loss peptides, medicinal peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Semaglutide, Tirzepatide, Retatrutide, and others.

ECHEMI Editorial Reference

Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

Certificates

Basic Info

Product Name:

Retatrutide

Other Name:

Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

CAS No.:

2381089-83-2

InChIKeys:

MLOLQJNKXBNWFW-SAGGEDDASA-N

Molecular Weight:

EC Number:

200-001-8

Color/Form:

White lyophilized

Categories:

Bulk Drug Intermediates

Characteristics

Water Solubility:

Soluble in water (5mg/ml).

Storage Conditions:

-20°C

Critical Temperature & Pressure:

-20°C

Research

Class:

Triple agonist — GCGR, GIPR, GLP-1R

Status:

Investigational (Phase 3)

Mechanism:

Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

EC50 (Human GCGR):

5.79 nM

EC50 (Mouse GIPR):

0.191 nM

EC50 (Mouse GLP1R):

0.794 nM

EC50 (Mouse GCGR):

2.32 nM

EC50 (Human GLP1R):

0.775 nM

EC50 (Human GIPR):

0.0643 nM

Source:

Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

Clinical Development:

NCT04881760; NCT05882045; NCT06354660

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Jastreboff et al. (2023) — Phase 2 Trial; FDA Drugs@FDA

Disclaimer:

Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

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Seller Information

Business Type:
Trader

Main Products:
peptides

Location:
No. 41-9, Fenghuangshan Road, Beiyuan Street, Tianqiao District, Jinan City, Shandong Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
3 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2026

Jinan Zhiwen Technology Co., Ltd. is a professional manufacturer and supplier of pharmaceutical raw materials, peptide compounds and fine chemicals. We own standardized laboratories and complete quality inspection procedures, strictly testing every batch for purity and consistency. Our product portfolio covers hot‑sale peptide APIs, chemical intermediates for biomedical research. Serving clients worldwide, we provide custom synthesis, sample support, flexible order volumes and end‑to‑end supply‑chain solutions. Committed to quality‑first principle, we strive to become your long‑term and dependable partner for biochemical raw‑material procurement.

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:

Peak season lead time: within 3 Workday; Off season lead time: within 1 Workday

Inquiry History

7503 Inquiries

Country	Product	Purchase Quantity	Date Posted
Malaysia	Retatrutide	20 MG	Oct 28, 2026
Brazil	Retatrutide	10	Oct 29, 2026
Australia	Retaturtide	100 MG	Oct 29, 2026
United States	Retatrutide 30mg and 50mg	20 PCS	Oct 29, 2026
Belgium	Retatrutide	1 MG	Oct 29, 2026
Romania	Retatrutide	10 G	Oct 29, 2026
United States	Retatrutide	2 MT	Oct 29, 2026
United States	Retatrutide	1 MT	Oct 29, 2026
United Kingdom	Retatrutide	1 PCS	Oct 28, 2026
United States	Retatrutide	30 MT	Oct 28, 2026
United Kingdom	Retatrutide	10 MT	Oct 28, 2026
United States	retatrutide	30 MG	Oct 28, 2026
Czech	Retatrutide	10 MG	Oct 28, 2026
Austria	retatrutide	30 MG	Oct 28, 2026
United States	Retatrutide	100 KG	Oct 28, 2026
Malta	Retatrutide	10 MT	Oct 28, 2026
United States	Retatrutide	600 MG	Oct 28, 2026
United States	Retatrutide	500 G	Oct 28, 2026
United States	Retatrutide	60 G	Oct 28, 2026
Croatia	Retatrutide	10 MG	Oct 28, 2026

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CAS 2381089-83-2 High Purity Retatrutide Peptides Weight LossTirzepatide Semaglutide factory price

Product Details

Seller Information

Inquiry History

Name

Retatrutide

CAS RN

2381089-83-2

Solubility

Dissolved in dimethyl sulfoxide

Storage condition

-20°C

EINECS

200-001-8

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