Supply High Purity 99% Pharmaceutical Raw Powder Antihypertensive CAS 21829-25-4 Powder Nifedipine
TDS 2 Inquiries
21829-25-4
Pharmaceutical Grade
99%
Shanghai
HNB
1kg/bag, 25kg/drum or as request
2026-05-07
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceYellow crystals. Melting point 172-174 ℃. Soluble in acetone, chloroform, ethyl acetate, dissolved in hot methanol, insoluble in water. It easily deteriorates in case of light.
Nifedipine appears as odorless yellow crystals or powder. Tasteless. (NTP, 1992)|Solid
Nifedipine appears as odorless yellow crystals or powder. Tasteless. (NTP, 1992)|Nifedipine is a dihydropyridine, a methyl ester and a C-nitro compound. It has a role as a calcium channel blocker, a vasodilator agent, a tocolytic agent and a human metabolite.|Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine]. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer durations of action. The most popular of the third generation dihydropyridines is [amlodipine]. Nifedipine was granted FDA approval on 31 December 1981.|Nifedipine is a Dihydropyridine Calcium Channel Blocker. The mechanism of action of nifedipine is as a Calcium Channel Antagonist.|Nifedipine is a first generation calcium channel blocker used to treat hypertension and angina pectoris. Nifedipine therapy is associated with a low rate of serum enzyme elevations and has been linked to several instances of clinically apparent acute liver injury.|Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)|A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.CertificatesBasic Info-
Product Name:
Nifedipine
Other Name:3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-,dimethyl ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-,dimethyl ester;Nifedipine;BAY-a 1040;4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine;Adalat;BAY 1040;2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine;Corynphar;Corinfar;Procardia;Fenihidine;Glopir;TN 873R;Cordafen;2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester;Cordaflex;Niphedipine;Dimethyl 4-(o-Nitrophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate;Procardia XL;Nifelate;Sepamit R;Adalat CC;Nifelan;Nifedipine retard;UV-ENP 349PINA;Macorel;Duranifin;Adalat 10;Nifangin;Anpine;Dignokonstant;Zenusin;Adalat LA;Nifedipres;Adalat GITS 30;Fedcor Retard;Alonix S;Fedipin;Coracten;Vasdalat;Fenamon SR;Adalat 20;Nifedirex LP;Nifelat;Ecodipin;Fenamon;Pidilat;Adalat CR;Nifedin;Nifedine;Hadipine;Cordalat;Myogard;Adalat LP;Nifecard;Adalat 5;Calcilat;Nifidine;Adalat GITS;Tibricol;Nificard;Osmo-Adalat;Chronadalate LP;Sepamit;Nyefax;Nifebene;Vasofed;Tensopin;Alpha-Nifedipine Retard;Cordipin;Corotrend;Ecodipin E;Nifelat Q;Adalat FT;Adapine;Citilat;Alonix;Cardifen;Dilcor;Normadil;Adalat PA;Dipinkor;Nifdemin;Adalat Oros;Nicardia;Apo-Nifed;Fedcor;Adalate;101539-70-2;101554-38-5;11104-22-6
CAS No.:21829-25-4
Molecular Formula:C17H18N2O6
InChIKeys:InChIKey=HYIMSNHJOBLJNT-UHFFFAOYSA-N
Molecular Weight:346.34
Exact Mass:346.33
EC Number:244-598-3
UNII:I9ZF7L6G2L
NSC Number:757242
DSSTox ID:DTXSID2025715
NCI Thesaurus Code:C29290
Color/Form:Yellow crystals
ATC Code:C08CA05|C - Cardiovascular system
HScode:29333990
Categories:
Characteristics-
PSA:
110
XLogP3:2
Appearance:yellow powder
Density:1.2109 (rough estimate)
Melting Point:172-174 °C
Boiling Point:475.3ºC at 760 mmHg
Flash Point:241.2ºC
Refractive Index:1.584
Water Solubility:H2O: <0.1 g/100 mL at 19.5 ºC;DMSO: soluble
Storage Conditions:2-8°C
Vapor Pressure:2.6X10-8 mm Hg at 25 deg C
Toxicity:Oral-rat LD50: 1022 mg/kg; Oral-Mouse LD50: 310 mg/kg
Flammability characteristics:Combustion produces toxic nitrogen oxide fumes; medicinal side effects: low blood pressure, cardiomyopathy, local blood flow disorders, hyperglycemia, psychosis
Henrys Law Constant:Henry's Law constant = 7.3X10-14 atm-cu m/mol at 25 °C (est)
Collision Cross Section:169.4 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Very light sensitive in solution|Hydroxyl radical reaction rate constant = 1.1X10-10 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions:Aqueous solutions are very sensitive to light. (NTP, 1992). Insoluble in water.
Reactive Group:Amines, Phosphines, and Pyridines
Reactivity Profile:NIFEDIPINE is sensitive to light.
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Nifedipine liquid-filled capsules should be protected from light and moisture and stored in tight, light-resistant containers at a temperature of 15-25 deg C, and extended-release tablets of the drug should be protected from light and moisture and stored in tight, light-resistant containers at a temperature less than 30 deg C.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China
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Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2017
Company Certificates-
ISO
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ISO
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Germany
Nifedipine
160 KG Dec 31, 2025 
Egypt
Nifidipine
1 KG May 12, 2024 Post an enquiry for this product
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