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Boc-D-Leu-OH buy - large image1
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Boc-D-Leu-OH

Unit Price: Get Latest Price
CAS No.:

16937-99-8

Grade:

Reagent Grade

Content:

95%

Port:

CHINA

Brand:

Chongqing Yuhan Technology Co., Ltd.

Packaging:

5g/bottle or 25kg/drum

Price valid (until):

2026-05-09

Company Type:
Trader
Location:
China
Qualification:
Main Products:

CARBONOCHLORIDOTHIOIC ACID,5-OCTYLESTER

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    1. N-Boc-Protected D-Amino Acid

    BOC-D-leucine is an N-tert-butoxycarbonyl (Boc) protected form of the non-natural D-enantiomer of leucine . The Boc group serves as a temporary protecting group for the amino function, which can be selectively removed under mild acidic conditions (e.g., TFA) without affecting other acid-labile protecting groups . This protection strategy is fundamental in peptide synthesis, allowing for controlled, stepwise assembly of peptides.


    2. Essential Building Block for Peptide Synthesis

    This compound is a crucial starting material and intermediate in solid-phase and solution-phase peptide synthesis . It provides the D-leucine residue in synthetic peptides, which can enhance resistance to enzymatic degradation and introduce specific conformational constraints. BOC-D-leucine has been employed in the synthesis of various bioactive peptides, including gastrin antagonists and analogs of the peptide antibiotic gramicidin S .


    3. High-Purity Research Chemical with Defined Optical Activity

    BOC-D-leucine is commercially available as a white to off-white crystalline powder with high purity (≥98% to 99%) . Key identification parameters include a melting point of 85-87°C and a specific optical rotation of [α]20D +25±1° (c=1 in AcOH), which confirms its D-configuration and chiral purity . These well-defined physical properties are essential for quality control in research and industrial applications.

    Items Specifications






    Basic Info
    Product Name:

    tert-Butoxycarbonyl-D-leucine

    Other Name:

    D-Leucine,N-[(1,1-dimethylethoxy)carbonyl]-;Leucine,N-carboxy-,N-tert-butyl ester,D-;N-[(1,1-Dimethylethoxy)carbonyl]-D-leucine;N-(tert-Butoxycarbonyl)-D-leucine;tert-Butoxycarbonyl-D-leucine;N-Boc-D-leucine;(R)-2-(tert-Butoxycarbonylamino)-4-methylpentanoic acid;D-Boc leucine;(R)-N-(t-Butoxycarbonyl)leucine;(2R)-2-[[[tert-Butoxy)carbonyl]amino]-4-methylpentanoic acid;(R)-2-[[tert-Butoxycarbonyl)amino]-4-methylpentanoicacid;(2R)-2-[[(tert-Butoxy)carbonyl]amino]-4-methylpentanoic acid;(2R)-4-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid

    CAS No.:

    16937-99-8

    Molecular Formula:

    C11H21NO4

    InChIKeys:

    InChIKey=MDXGYYOJGPFFJL-MRVPVSSYSA-N

    Molecular Weight:

    249.3

    Exact Mass:

    231.29

    BRN:

    2331060

    EC Number:

    1312995-182-4

    HScode:

    29241990

    Categories:

    Organic Reagents

    Characteristics
    PSA:

    84.86000

    XLogP3:

    2.33700

    Appearance:

    White fine crystals

    Density:

    1.061±0.06 g/cm3(Predicted)

    Melting Point:

    85-87 °C(lit.)

    Boiling Point:

    356.0±25.0 °C(Predicted)

    Flash Point:

    169.1±23.2 °C

    Refractive Index:

    25 ° (C=2, AcOH)

    Storage Conditions:

    −20°C

    Vapor Pressure:

    4.98E-06mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    CARBONOCHLORIDOTHIOIC ACID,5-OCTYLESTER

    Location:

    B9-2, LIANGFENG COMMUNITY, CHANGSHENGQIAO TOWN, NANAN DISTRICT, CHONGQING CITY,CHINA

    Payment Terms:

    TT against copy of documents,D/P,L/C

    Average lead Time:

    60

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2017

    Certifications:

    GSG,Awards,Certificate of Record for the Handling of Non-Pharmaceutical Precursor Chemicals, Category II,Certificate of Registration for Entities Handling Explosive Hazardous Chemicals,Registration form for foreign trade operators,Hazardous Chemicals Operating License,Certificate of Record for the Handling of Non-Pharmaceutical Precursor Chemicals, Category III,Customs Receipt of Registration for Import/Export Consignees and Consignors,Business License

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