 Home > Biochemical Engineering > Polypeptide > Degarelix Acetate for Sale > GMP factory supply Degarelix CAS 214766-78-6 with DMF

GMP factory supply Degarelix CAS 214766-78-6 with DMF buy - large image1

GMP factory supply Degarelix CAS 214766-78-6 with DMF buy - image1

GMP factory supply Degarelix CAS 214766-78-6 with DMF

Name: GMP factory supply Degarelix CAS 214766-78-6 with DMF
Brand: Bovita
SKU: pr2604102618
Price: 300 USD
Availability: InStock

3 Inquiries

Unit Price: Get Latest Price 

CAS No.:

214766-78-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

BEIJING

Brand:

Bovita

Packaging:

aluminium foil bag

Price valid (until):

2026-05-10

Contact Supplier

 Chat Now

Bovitabiomed

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Peptides Powder,Dietary Supplements Powder,APIs Active Pharmaceutical Ingredientsal ingredient,Pharmaceutical Intermediates,Food Additives,Pharmaceuticals Machinery

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Details: Degarelix Acetate CAS 214766-78-6

Product Overview

Degarelix (also known as degarelix acetate) is a synthetic, long‑acting gonadotropin‑releasing hormone (GnRH) receptor antagonist peptide. It acts by competitively blocking GnRH receptors in the pituitary gland, rapidly suppressing luteinizing hormone (LH) and follicle‑stimulating hormone (FSH) secretion, thereby reducing testosterone production without the initial testosterone surge typical of GnRH agonists. It is widely used in endocrine and urological research focused on hormone‑dependent conditions.

Product Specifications

Parameter	Details
Product Name	Degarelix Acetate
CAS Number	214766-78-6
Synonyms	FE-200486, Firmagon
Molecular Formula	C₈₂H₁₀₃ClN₁₈O₁₆
Molecular Weight	≈ 1632.28 g/mol
Peptide Type	Synthetic Decapeptide
Purity	≥99.0% (HPLC Tested)
Appearance	White to off-white lyophilized powder
Solubility	Soluble in water, aqueous buffers
Storage	Lyophilized: -20°C long-term, 2–8°C short-term Reconstituted: 2–8°C, use within 7 days
Form	Lyophilized Powder
Grade	Research Use Only (RUO)
Packaging	1mg, 5mg, 10mg, 50mg, 100mg sealed vials
Shelf Life	2 years under recommended storage

Key Features & Benefits

High Purity: ≥99% verified by HPLC and MS for reliable research outcomes.
Direct GnRH Receptor Antagonism: No testosterone flare, enabling consistent hormone‑suppression studies.
Long‑acting Pharmacology: Suitable for sustained‑release and long‑term animal model research.
Excellent Stability: Lyophilized form ensures stability during transport and storage.
Strict QC Standards: Full CoA included with each batch.

Research Applications

Prostate cancer research (hormone‑dependent tumor models)
GnRH receptor pharmacology and signaling studies
Testosterone regulation and hypothalamic–pituitary–gonadal axis research
Hormone ablation therapy mechanism studies
In vitro and in vivo endocrine pharmacology assays
Urological and reproductive system research

Mechanism of Action

Degarelix binds competitively and reversibly to pituitary GnRH receptors, inhibiting endogenous GnRH stimulation. This rapidly reduces LH and FSH secretion, which in turn suppresses testicular testosterone production. Unlike GnRH agonists, degarelix does not cause an initial testosterone surge, making it ideal for research requiring immediate and sustained androgen deprivation.

Storage & Handling

Store lyophilized powder at −20°C, protected from light and moisture.
Avoid repeated freeze–thaw cycles.
Reconstitute with sterile water or buffer prior to use.
Aliquot and refreeze at −20°C for extended storage.

Important Disclaimer

FOR RESEARCH USE ONLY (RUO). NOT FOR HUMAN, THERAPEUTIC, OR VETERINARY USE.

This product is sold exclusively to qualified researchers and laboratories. It is not intended for clinical, diagnostic, therapeutic, or household use. Users are responsible for compliance with all local, national, and international regulations governing research chemicals and peptides.

Quality Assurance

HPLC purity ≥99%
Identity confirmed by Mass Spectrometry (MS)
Endotoxin tested
TSE/BSE-free, no animal-derived materials
Sterile filtration and lyophilization
Full Certificate of Analysis (CoA) provided

ECHEMI Editorial Reference

Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
Degarelix is a polypeptide.|Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in testosterone is important in treating men with advanced prostate cancer. Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which are D-amino acids. FDA approved on December 24, 2008.|Degarelix is a Gonadotropin Releasing Hormone Receptor Antagonist. The mechanism of action of degarelix is as a Gonadotropin Releasing Hormone Receptor Antagonist. The physiologic effect of degarelix is by means of Decreased GnRH Secretion.|Degarelix is a parenterally administered, gonadotropin releasing hormone (GnRH) antagonist that effectively blocks androgen production and is used to treat advanced prostate cancer. Degarelix therapy is associated with serum enzyme elevations during therapy, but has yet to be linked to instances of clinically apparent acute liver injury.|Degarelix is a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes.

Basic Info

Product Name:

Degarelix Acetate

CAS No.:

214766-78-6

Molecular Formula:

C82H103ClN18O16

InChIKeys:

MEUCPCLKGZSHTA-XYAYPHGZSA-N

Molecular Weight:

1632.28

Exact Mass:

1630.748779

EC Number:

1312995-182-4

UNII:

SX0XJI3A11

NCI Thesaurus Code:

C48385

ATC Code:

L02BX02|L - Antineoplastic and immunomodulating agents

Categories:

Polypeptide

Characteristics

PSA:

513

XLogP3:

4.45

Density:

1.3±0.1 g/cm3

Refractive Index:

1.620

Experimental Properties:

White to off-white amorphous powder /Degarelix, acetate anhydrate/

See More Degarelix Acetate Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 1A

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H360 May damage fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Degarelix Acetate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptides Powder,Dietary Supplements Powder,APIs Active Pharmaceutical Ingredientsal ingredient,Pharmaceutical Intermediates,Food Additives,Pharmaceuticals Machinery

Location:
Room 403 No.62 of Shan Shui Huihao Gardan, Dou Dian Town,Fangshan District, Beijing,China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2026

Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to bridging scientific excellence with global wellness demands, with a core focus on serving the North American and European markets.

Company Profile

Inquiry History