High Purity Factory Supply CAS 106685-40-9 Adapalene Powder

Adapalene is a retinoic acid compound that has been proven to have anti-inflammatory properties in in vivo and in vitro inflammation models. It has a stable chemical structure and is not easily decomposed in air and light. The mechanism of action is the same as that of retinoic acid, and it can bind to specific retinoic acid nuclear receptors. The difference is that adapalene does not bind to protein-binding cytoplasmic receptors.

As a third-generation retinoic acid drug, adapalene is more powerful than all-trans retinoic acid and other retinoic acid drugs in regulating epidermal cell differentiation, inhibiting the proliferation and keratinization of hair follicle orifice keratinocytes, and inhibiting sebaceous gland cells. In addition to its effects on hyperplasia and dissolving horn plugs and acne, it also has a strong anti-inflammatory effect. Because of its unique stability, its efficacy and tolerability are significantly improved compared to other retinoic acid drugs.

The retinoic acid analogue, adapalene, is a RARβ and RARγ receptor agonist. Adapalene inhibits cell proliferation and induces apoptosis in colorectal cancer cells in vitro. Adapalene gel is an effective acne treatment.

Xian Harmonious Natural Bio- Technology Co., Ltd was founded in 2017, and located in Xian International Logistics Industrial Zone, Xian City. Shaanxi Province, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainless extraction equipment.

We have 2 sales deparments over 20 people and sell our products allover the word. We also have strong professional research and development team talented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
HNB mainly engaged in export of products incuding,without limitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acids minerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond and Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
Passion to innovate, Power to deliver !

Q1 Can i get some samples?

A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2 How to start orders or make payments?

A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information.

Payment by T/T,or Paypal or Escrow(Alibaba).

Q3 How to confirm the Product Quality before placing orders?

A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier

to us and take the samples. You can send us your product specifications and requests,we will manufacture

the products according to your requests.

Q4 What’s your MOQ?

A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge

is 100% paid.

Q5 How about delivery leadtime?

A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6 Is there a discount?

A6 Different quantity has different discount.

Q7 How do you treat quality complaint?

A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem

caused by us, we will send you free goods for replacement or refund your loss.

Q8 How to contact us ?

A8 You can choose your interested products and send inquiry to us.