ARA-290 (Cibinetide)

I. Basic Chemical Identification

• Common Names: ARA-290, Cibinetide
• Amino Acid Sequence: Gln-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser (linear undecapeptide, EPO derivative)
• CAS Registry Number: 1208243-50-8
• Molecular Weight: 1257.31 Da
• Molecular Formula: C₅₁H₈₄N₁₆O₂₁

II. Key Physicochemical Properties

• Appearance: White lyophilized powder, no visible foreign matter
• Solubility: Soluble in purified water and dimethyl sulfoxide (DMSO), easily soluble in aqueous solution
• Stability: Stable in a dark, sealed and dry environment; freezing at -20℃ is recommended for long-term storage, avoiding repeated freeze-thaw

III. Synthesis & Quality Standards

Adopting the standard Fmoc Solid-Phase Peptide Synthesis (SPPS) process, the process is mature and controllable, which can accurately ensure the integrity of the amino acid sequence, and the purity is easy to control.

• HPLC Purity: ≥98.0% (≥99.5% for research grade)
• Key Indicators: Qualified amino acid composition, moisture ≤8.0%, heavy metal (Pb) ≤10 ppm

IV. Storage & Transportation Requirements

• Packaging: Sealed packaging with built-in desiccant to prevent moisture absorption
• Storage: Frozen at -20℃, protected from light and moisture, avoiding high temperature and repeated freeze-thaw; it is recommended to use within 1 month after dissolving in solvent
• Transportation: General cargo channel, properly protected to avoid packaging damage and moisture absorption; blue ice transportation can be provided according to requirements

V. Applications & Specifications

• Main Applications: Life science research; R&D of fine chemical intermediates and pharmaceutical intermediates
• Specifications: Marked "For Research/Chemical Raw Material Use Only", strictly prohibited for clinical medical use, complying with relevant industrial standards