Premium Quality MOTS-C Peptide Powder CAS 1627580-64-6 Direct Manufacturer

What is MOTS-C?

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid microprotein encoded by mitochondrial DNA. Unlike traditional mitochondrial proteins, MOTS-c acts as a signaling molecule that regulates systemic metabolic homeostasis.

Mechanism of Action

MOTS-c works through two primary pathways：

1. AMPK Pathway Activation (Metabolic Core)

• Inhibits folate cycle and de novo purine synthesis → AICAR accumulation → AMPK activation

• AMPK is the cell’s "energy sensor" that promotes glucose uptake, fatty acid oxidation, and mitochondrial biogenesis

2. CK2 Kinase Binding (Latest Discovery 2024)

• MOTS-c directly binds to and activates the CK2α subunit (KD = 1 nM)

• This mechanism explains its regulatory effects on muscle mass and glucose metabolism

Key Features & Potential Benefits

✅ 1. Glucose & Lipid Metabolism

Enhances insulin sensitivity, improves glycemic control, prevents diet-induced obesity

✅ 2. Muscle Health

Prevents muscle atrophy, promotes myotube formation, enhances muscle glucose uptake

✅ 3. Anti-inflammatory & Neuro protection

Inhibits NF-κB pathway, reduces neurological deficits after traumatic brain injury

✅ 4. Cardiovascular Protection

Improves LVEF and LVFS in diabetic cardiomyopathy, reduces fibrosis and apoptosis

✅ 5. Exercise-mimetic Effects

Exercise induces endogenous MOTS-c; exogenous supplementation mimics some exercise benefits

Because of its potential benefits in supporting glucose regulation and metabolic activity, MOTS-C is widely supplied for scientific research and laboratory applications.

We provide high purity MOTS-C peptide powder with stable quality, competitive pricing, and bulk supply availability for research use.

Shipping Record

FAQ

Q: How to order this product?

A:You can send us your Purchase order, or just send a simple confirmation by email or message, we will send you order confirmation, then you can make your order accordingly.

Q: How long can I receive my ordered goods?

A: We offer door-to-door service. Typically, you can expect to receive the goods within 8-15 days after shipment. *(Note: This excludes order processing time, which usually takes 1-2 days.)*

Q: What's your MOQ?

A:For the regular products, our MOQ is 1box.

Q: Is there a discount?

A: Yes, we offer significant discounts for bulk orders. The discount rate will increase with the order quantity. Please let us know your target quantity, and we will provide you with a best price accordingly.

Q: Is the product in stock?
A: Our inventory changes quickly. For the most current availability, please contact us directly with the product model number. We will confirm the status for you within one business day.