Dibucaine/Cinchocaine/Cinchocaine/ INN / BAN
85-79-0
Pharmaceutical Grade
99%
shenzhen
Flying
10g/1kg/ 10kg/ 25kg
2026-05-29
vitamin
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceDibucaine is a local anesthetic of the amide type now generally used for surface anesthesia.Target: Sodium ChannelDibucaine is an amide local anesthetic. Dibucaine reduced the degradation of BSA-gold complex in the reservosomes, which was not caused either by an inhibition of the whole proteolytic activity of the parasite or by a reduction on the expression levels of cruzipain [1].Dibucaine, a quaternary ammonium compound, inhibited SChE to a minimum within 2 min in a reversible manner.
Solid
Cinchocaine is a monocarboxylic acid amide that is the 2-(diethylamino)ethyl amide of 2-butoxyquinoline-4-carboxylic acid. One of the most potent and toxic of the long-acting local anesthetics, its parenteral use was restricted to spinal anesthesia. It is now generally only used (usually as the hydrochloride) in creams and ointments and in suppositories for temporary relief of pain and itching associated with skin and anorectal conditions. It has a role as a topical anaesthetic. It is a monocarboxylic acid amide, a tertiary amino compound and an aromatic ether.|A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)|Dibucaine is a Standardized Chemical Allergen. The physiologic effect of dibucaine is by means of Increased Histamine Release, and Cell-mediated Immunity.|Dibucaine is a quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.Basic Info-
Product Name:
Dibucaine
Other Name:4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-;Cinchoninamide,2-butoxy-N-[2-(diethylamino)ethyl]-;2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide;2-Butoxy-N-[2-(diethylamino)ethyl]cinchoninamide;Dibucaine;Dibucaine base;Nupercainal;Nupercaine;N-[2-(Diethylamino)ethyl]-2-butoxycinchoninamide;Cinchocaine;Dermacaine;Percamine;NSC 159055;2-Butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide;8023-28-7;8055-06-9
CAS No.:85-79-0
Molecular Formula:C20H29N3O2
InChIKeys:InChIKey=PUFQVTATUTYEAL-UHFFFAOYSA-N
Molecular Weight:343.46
Exact Mass:343.46
EC Number:201-632-1
UNII:L6JW2TJG99
NSC Number:159055
DSSTox ID:DTXSID3045271
NCI Thesaurus Code:C28984
Color/Form:Colorless or almost colorless powder
ATC Code:C - Cardiovascular system|D - Dermatologicals|N - Nervous system|S - Sensory organs
HScode:2933499090
Categories:
Characteristics-
PSA:
54.5
XLogP3:4.2
Appearance:Solid
Density:1.1±0.1 g/cm3
Melting Point:64 °C
Boiling Point:491.5±55.0 °C at 760 mmHg
Flash Point:251.1±31.5 °C
Refractive Index:1.549
Water Solubility:68.01mg/L(temperature not stated)
Odor:Odorless
PKA:8.85None
Dissociation Constants:8.85
Collision Cross Section:196.2 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Experimental Properties:BITTER, ACRID TASTE; PROLONGED ANESTHETIC ACTION WHEN APPLIED TO TONGUE /DIBUCAINE HYDROCHLORIDE/|Somewhat hygroscopic.
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Serious eye damage, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H302 Harmful if swallowed
H318 Causes serious eye damage
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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