Omarigliptin (MK-3102) CAS1226781-44-7
2 Inquiries
1226781-44-7
Industrial Grade
99%
shanghai
Dideu
25kg/Cardboard Drum
2035-07-19
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceOmarigliptin(MK-3102) is a potent, selective and long-acting DPP-4 inhibitor with IC50 of 1.6 nM; highly selective over allproteases tested (IC50 > 67 μM).IC50 value: 1.6 nM [1]Target: DPP-4 inhibitorin vitro: Omarigliptin has weak ion channel activity (IC50 > 30 μM at IKr, Cav1.2, and Nav1.5). An expansive selectivity counterscreen (168 radioligand binding or enzymatic assays) was carried out at MDS Pharma. An IC50 > 10 μM was obtained in all assays. in vivo: When orally administered 1
Omarigliptin is a pyrrolopyrazole.|Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.Basic Info-
Product Name:
Omarigliptin
Other Name:2H-Pyran-3-amine,2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-,(2R,3S,5R)-;(2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine;(2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine;Omarigliptin;1446021-64-2
CAS No.:1226781-44-7
Molecular Formula:C17H20F2N4O3S
InChIKeys:InChIKey=MKMPWKUAHLTIBJ-ISTRZQFTSA-N
Molecular Weight:398.43
Exact Mass:398.43
EC Number:1592732-453-0
UNII:CVP59Q4JE1
DSSTox ID:DTXSID70153678
Categories:
Characteristics-
PSA:
98.8
XLogP3:0.3
Density:1.6±0.1 g/cm3
Flash Point:274.0±32.9 °C
Refractive Index:1.689
Hazard IdentificationClassification of the substance or mixture
Specific target organ toxicity â repeated exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P319 Get medical help if you feel unwell.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Location:
https://www.dideu.com/en/
-
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
7 days
-
Total Annual Revenue:
Above $100 million
-
Total Employees:
Above 1000
-
Year of Establishment:
2016
Company Certificates-
ISO Certificate
-
REACH
">Company Profile -
-
Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Canada
Omarigliptin
1 KG May 8, 2026
Serbia
omarigliptin
10 Feb 6, 2024 Post an enquiry for this product
More from this Seller
-
-
-
2- (2 '- hydroxy-3', 5 '- diterpentylphenyl) benzotriazole
National Grade / 99%
-
-
-
-
Thiourea 99% Powder 62-56-6 Dideu
Chemical Grade / 99%
$1/KG FOB
-
-
-
-
Potassium hydroxide CAS1310-58-3 high-quality plant extract, reliable bulk and sample supply for global buyers
Pharmaceutical Grade / 99.9%
$1/MT FOB
-
-
-
-
Phenylacetylene 99% Liquid Dideu
Industrial Grade / 99%
-