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trans-ISRIB-A17 98%

Name: trans-ISRIB-A17 98%
Brand: Dideu
SKU: pr2605091491
Price: 1500 USD
Availability: InStock

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CAS No.:

1628478-15-8

Grade:

Pharmaceutical Grade

Content:

98%

Port:

Shaanxi

Brand:

Dideu

Packaging:

1G/BAG

Price valid (until):

2026-06-09

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Shaanxi Dideu Medichem Co. Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

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Description

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)-

trans-ISRIB (CAS 1597403-47-8) is a potent, blood-brain barrier-permeable Integrated Stress Response (ISR) inhibitor (IC${}_{50}$ = 5 nM). Supplied at $\ge $98% purity (HPLC), it reverses the effects of eIF2α phosphorylation, restores translation capacity, and enhances cognitive memory in rodents

Key Aspects of trans-ISRIBMechanism: Acts downstream of PERK by inhibiting the effects of eIF2α phosphorylation and targeting eIF2B-mediated signaling.Applications: Commonly used in research to study cognitive enhancement and to reverse cellular stress.CEPT Cocktail: Component of the CEPT cocktail (Chroman 1, Emricasan, Polyamines, and Trans-ISRIB) used to enhance human pluripotent stem cell survival, particularly after cryopreservation.Solubility: Soluble in DMSO (approx. 2 mg/mL) or dimethyl formamide.Storage: Store at +4°C

Items	Specifications
Appearance	White to off-white powder
Identity by MS	341.16±1
Heavy Metal	≤ 1000 PPM
Clarity and color of Solution	Clear and colorless
Moisture	≤ 2.0%
Purity	≥ 98.0%

Research & Reference Note

trans-ISRIB-A17 98% is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Authoritative sources

Disclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals

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Basic Info

Product Name:

Pharmaceutical Intermediate Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chloro-3-fluorophenoxy)- CAS1628478-15-8

CAS No.:

1628478-15-8

Categories:

Seller Information

Business Type:
Manufactory

Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

Location:
https://www.dideu.com/en/

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
Above $100 million

Total Employees:
Above 1000

Year of Establishment:
2016

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- ISO Certificate
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Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	trans-ISRIB-A17	1 G	May 9, 2026

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trans-ISRIB-A17 98%

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