307297-39-8 Epitalon 1g Epithalon Freeze-dried powder Eptifibatide / Selank /dihexa / Semax / N acetyl selank /epitalon
ISO TDS 53 Inquiries
307297-39-8
Pharmaceutical Grade
99%
g
HORLDEN
10mg/vial, 10 vials a box./1g
2026-06-13
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceEpitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa[1].Certificates
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TDS
Basic Info-
Product Name:
Epitalon
Other Name:AE-0 peptide;Ala-Glu-Asp-Gly;alanyl-glutamyl-aspartyl-glycine;epitalon;epithalon;epithalone;307297-39-8;UNII-O65P17785G
CAS No.:307297-39-8
Molecular Formula:C14H22N4O9
InChIKeys:HGHOBRRUMWJWCU-FXQIFTODSA-N
Molecular Weight:390.346
Exact Mass:390.138672
Categories:
Characteristics-
PSA:
225
XLogP3:-2.02
Density:1.5±0.1 g/cm3
Boiling Point:959.8±65.0 °C at 760 mmHg
Flash Point:534.3±34.3 °C
Refractive Index:1.559
Research-
Class:
Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator
Status:Research compound — Not FDA approved
Mechanism:A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.
EC50 (HGF Binding KD):65 pM
Activity note:Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).
Source:Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.
Clinical Development:
References-
PubChem:UNII:Literature:
Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status
Disclaimer:Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
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Seller Information
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Business Type:
Trader
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Main Products:
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide
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Location:
9th Floor, Room 923, Building 3, Shiyuan Daguan, Xingtai 1st Street, Chanba Ecological District, Xi'an City, Shaanxi Province
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Payment Terms:
100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History53 Inquiries
Country Product Purchase Quantity Date Posted 
United States
N-Acetyl Epitalon Amidate CAS 307297-39-8 Epitalon 99% White Powder 99% N-Acetyl Epitalon Amidate
1 Oct 4, 2023
United States
N-Acetyl Epitalon Amidate CAS 307297-39-8 Epitalon 99% White Powder 99% N-Acetyl Epitalon Amidate
1 G Oct 7, 2023
United States
Epitalon, NAD+, DSIP, 5-Amino-1MQ, PEG-MGF
1 May 9, 2026
United States
epitalon
500 MG Aug 23, 2026
United States
Epithalon
0.1 G Jul 13, 2026 
Canada
Epitalon
20 MG Jun 8, 2026
United States
epithalon
10 MG Jun 3, 2026
United States
Epitalon
100 MG May 17, 2026 
Netherlands
N-Acetly Epitalon
1 G Apr 27, 2026
United States
Peptides
1 MT Apr 26, 2026 
Nigeria
Cagrilinitide
10 G Apr 17, 2026
United States
Epithalon
500 MG Mar 25, 2026
United States
Epitalon
10 MT Mar 24, 2026
United States
Epitalon
1 PCS Mar 10, 2026
United States
epitalon
1 MG Feb 18, 2026
United States
Epithalin
100 G Jan 20, 2026
United States
Epitalon
2 G Jan 6, 2026
United States
Na Epitalon Amidate
1 G Nov 28, 2025 
South Korea
epitalon
1 G Feb 22, 2025
South Korea
N Acetyl Epitalon
2 G Feb 18, 2025 Post an enquiry for this product
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