Reduced Nicotinamide Adenine Dinucleotide NADH

Reduced nicotinamide adenine dinucleotide (NADH), also known as reduced coenzyme I, is a naturally occurring coenzyme in our body. It is the reduced form of oxidized Coenzyme I, NAD ⁺ ,participates in thousands of key biochemical reactions in the body. It is the core substance that maintains normal physiological functions of cells. NADH can directly act on the mitochondrial energy metabolism pathway, participate in oxidative phosphorylation reactions, promote ATP production, supply energy to various organs of the body, alleviate fatigue, and improve metabolic levels. At the same time, it has strong endogenous antioxidant effects, which can clear free radicals, reduce oxidative stress damage, and delay cell aging. As age increases, the body's ability to synthesize NADH continues to decline. Supplementing with high-purity NADH can quickly increase the levels of coenzymes in the body, repair cell damage, and improve the body's condition. It is a high-quality bioactive raw material used for anti-aging maintenance and energy regulation, and can be applied in dietary supplements and scientific research fields.

Product name: Reduced Nicotinamide Adenine Dinucleotide (NADH)

CAS number: 606-68-8

Molecular formula: C21H27N7Na2O14P2

Molecular weight: 709.4

EINECS number: 210-123-3

Purity: >95%

Grade: Food grade, Reagent grade available

Pakcage: 5kgs or 10kgs per bag

1、 Endogenous generation in the human body

NADH is synthesized in human cells through metabolic pathways such as glycolysis, tricarboxylic acid cycle, etc. It is mainly produced in mitochondria and cytoplasm and is the main source of the body; But with age increase, the endogenous synthesis will significantly decrease.

2、 Natural food sources (low content, limited absorption)

Animal based foods such as animal organs,meat, deep-sea fish, poultry meat, egg yolks, plant based foods such as avocado, broccoli, mushrooms, and nuts also contain small amounts of NADH. It is difficult to achieve effective supplementation doses in daily diet. In addition, NADH in food has poor stability and is easily decomposed when exposed to high temperatures. After oral administration, most of it is destroyed by digestive enzymes and has a low absorption rate.

3、 Artificial synthesis

Enzymatic synthesis: Using NAD ⁺ as a substrate, it is prepared by reductase catalysis, with high purity and good activity, and is widely used in health products and scientific research materials.

Chemical synthesis method: chemical reduction preparation, low cost, high impurities, mostly used for laboratory research.

NADH is a kind of coenzyme, it could be used in the following application:

1, Enzymatic reaction 

2, Diagnostic kits

3, New drug developement 

4, Distary supplement 

5, Pet health products