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Aprocitentan, CAS:1103522-45-7

Name: Aprocitentan, CAS:1103522-45-7
Brand: Wuhan pnq
SKU: pr2605281341
Price: 10.3 USD
Availability: InStock

Unit Price:

$10.3-11.33/G FOB

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CAS No.:

1103522-45-7

Grade:

Chemical Grade

Content:

99%

Port:

Shanghai

Brand:

Wuhan pnq

Packaging:

Aluminum foil bag

Price valid (until):

2026-09-30

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Wuhan Pnq Int Trade Co., Ltd

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

30 days

Qualification:

Main Products:

Apigenin,PQQ,NMNH

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Product Description
Seller Information
History Price

Description

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Q1: What's your MOQ?

A:It depends on different products,we can accept sample order or provide free sample for your test.

Q2:How about delivery leadtime?

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q3: Is there a discount?

A:Different quantity has different discount.

Q4:How to start orders or make payments?

A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T or Bitcoin.

Q5: How do you treat quality complaint?

A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q6:We don't know you at all, how can we trust you?

A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.

Q7:Do you test all your goods before delivery?

A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.

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High purity Chemical

1, Aprocitentan, CAS:1103522-45-7

ECHEMI Editorial Reference

ACT-132577 is the major and pharmacologically active metabolite of macitentan, which is dual ETA/ETB antagonist designed for tissue targeting.
ACT-132577 is a member of the class of sulfamides in which one of the amino groups of sulfonamide is substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. An active metabolite of macitentan (obtained by oxidative depropylation), an orphan drug used for the treatment of pulmonary arterial hypertension. It has a role as an antihypertensive agent, an endothelin receptor antagonist, a drug metabolite and a xenobiotic metabolite. It is an aromatic ether, an organobromine compound, a member of pyrimidines and a member of sulfamides. It derives from an ethylene glycol.|Aprocitentan is under investigation in clinical trial NCT03541174 (A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety).

Basic Info

Product Name:

ACT-132577

Other Name:

ACT-132577;N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]sulfamide;N-Despropyl Macitentan;Aprocitentan;Despropyl Macitentan

CAS No.:

1103522-45-7

Molecular Formula:

C16H14Br2N6O4S

InChIKeys:

DKULOVKANLVDEA-UHFFFAOYSA-N

Molecular Weight:

546.19316

Exact Mass:

543.91600

UNII:

MZI81HV01P

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

150.59000

XLogP3:

4.38590

Density:

1.841±0.06 g/cm3(Predicted)

Boiling Point:

705.0±70.0 °C(Predicted)

See More ACT-132577 Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More ACT-132577 Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Apigenin,PQQ,NMNH

Location:
Room 1006, Building C6, Economic Development Wanda, Caidian District, Wuhan City, Hubei Province

Payment Terms:
100% TT in advance

Average lead Time:
30 days

Total Annual Revenue:
Less than $1 million

Total Employees:
5-10

Year of Establishment:
2021

Wuhan PNQ trade located in Wuhan, China, is an innovative natural products manufacturer and supplier that offers raw powders as dietary ingredients, food and beverage additives, sports nutrition supplements.
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Aprocitentan, CAS:1103522-45-7

Product Description

Seller Information

History Price

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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