Tesa purity of over 99% TSM

TSM is a synthetic growth hormone-releasing hormone (GHRH) analog composed of 44 amino acids. Its structure has been modified from natural GHRH to significantly improve stability and half-life, preventing rapid degradation by DPP-IV enzymes. It mimics GHRH secreted by the hypothalamus, physiologically stimulating the pituitary gland to release growth hormone (GH) in a pulsatile manner, thereby regulating body composition, promoting fat breakdown, and improving metabolic health.
Full name: TSM Acetate
Other names:TSM, TH9507, EGRIFTA
CAS: 901758-09-6
Purity: ≥99% (HPLC verified)
Appearance: White lyophilized powder
Specifications: 5mg/bottle, 10mg/bottle (customizable)
Molecular weight: ≈5135.9 Da
Half-life: ≈26 minutes (long-lasting, stable, pulsed release)

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1. Effectively reduces visceral fat (VAT)
Clinical studies have shown that 26 weeks of continuous use can reduce visceral fat by approximately 15–18%. The effect is most significant on deep abdominal fat, which is associated with metabolic risks. Subcutaneous fat isn’t affected by this treatment.
2. Naturally promotes GH/IGF-1 secretion – safe and gentle
It stimulates the pituitary gland to release GH in a physiological manner, rather than providing exogenous GH directly. This approach preserves the hypothalamic-pituitary feedback mechanism, thereby reducing the risks of  resistance, edema, and blood sugar fluctuations.
3. Improve metabolic indicators and protect the cardiovascular system
Reduces triglycerides, increases high-density lipoprotein, improves  sensitivity, and reduces the risk of metabolic syndrome and cardiovascular diseases. National Center for Biotechnology Information.
4. Maintain lean muscle mass and improve body composition
Promotes protein synthesis, reduces muscle breakdown, helps with fat loss while protecting muscles. Ideal for body composition optimization and anti-aging research.
5. Improving aging-related metabolic decline (under research)
For middle-aged and elderly individuals experiencing decreased growth hormone levels (somatopause), this treatment can restore GH rhythms, increase energy levels, and improve body fat distribution.

1. Activating GHRH receptors: By mimicking endogenous GHRH, it binds precisely to pituitary receptors, thereby triggering pulsatile release of GH.
2. Resistance to enzyme degradation: N-terminal structural modifications enhance resistance to DPP-IV hydrolysis, resulting in a longer half-life and more stable activity.
3. Dual pathways of lipolysis and synthesis: GH activates lipolysis in fat cells and promotes fatty acid oxidation. At the same time, it stimulates muscle protein synthesis.
4. Feedback-regulated safety: Does not disrupt the body’s GH regulatory mechanism, thereby avoiding long-term side effects associated with high GH levels

✅ High-purity quality control: ≥99%. A COA quality inspection report is provided for each batch.
✅ Stable structure: The lyophilized powder can be stored at -20°C for long periods. It remains stable, does not degrade easily, and maintains high activity.
✅ Thorough clinical validation: The drug’s active ingredient (EGRIFTA) has been approved by the FDA, with substantial data from Phase III clinical trials supporting its efficacy.
✅ Safe and user-friendly: No water retention, no feminizing effects, no significant impact on blood sugar levels. Good tolerance.

Research on the Mechanisms of Visceral Fat and Metabolic Syndrome
Body Composition Optimization (Fat Loss and Muscle Retention) and Body Shaping Research
Research on somatopause, the decline of growth hormone associated with aging
Research on Non-Alcoholic Fatty Liver Disease (NAFLD) and Lipid Metabolism Disorders
Research on Interventions and Protections against Cardiovascular and Metabolic Risks
Research on Sports Nutrition, Physical Performance Improvement, and Recovery