ACE031 Lyophilized Powder| High Purity Raw Peptide| Factory Supply
1 Inquiries
595-33-5
Pharmaceutical Grade
99%
GUANGZHOU
HuiTu
1mg/vial 10vials/box
2026-06-29
Peptides,Retatrutide,GHK-CU
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceMegestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HegG2.Target: Progesterone ReceptorMegestrol acetate, also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, and sometimes abbreviated as MGA or MA, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects. Megestrol acetate is a good candidate for muscle wasting treatment and future
Megestrol acetate is a steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer. It has a role as an antineoplastic agent, an appetite enhancer, a contraceptive drug, a progestin and a synthetic oral contraceptive. It is a steroid ester, an acetate ester, a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It derives from a megestrol.|17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.|Megestrol Acetate is the acetate salt form of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone with potential anti-estrogenic and antineoplastic activity. Mimicking the action of progesterone, megestrol acetate binds to and activates nuclear progesterone receptors in the reproductive system, and causes the ligand-receptor complex to be translocated to the nucleus where it binds to and promotes expression of target genes. This leads to an alteration in protein synthesis, which modulates cell growth of reproductive tissues. Due to the negative feedback mechanism seen with progesterone, megestrol also blocks luteinizing hormone (LH) release from the pituitary gland, thereby leading to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. Furthermore, without stimulation of LH, estrogen release from the ovaries is stopped, hence impedes the growth of estrogen-sensitive tumor cells.|Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)Research & Reference NoteACE031 Lyophilized Powder| High Purity Raw Peptide| Factory Supply is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Authoritative sourcesDisclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals
Basic Info-
Product Name:
Megestrol acetate
Other Name:Pregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-methyl-;Pregna-4,6-diene-3,20-dione,17-hydroxy-6-methyl-,acetate;17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione;BDH 1298;5071;SC 10363;17α-Acetoxy-6-dehydro-6-methylprogesterone;DMAP;17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;Megestrol acetate;6-Methyl-6-dehydro-17α-acetoxyprogesterone;6-Methyl-17α-hydroxy-Δ6-progesterone acetate;17α-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;6-Dehydro-6-methyl-17α-acetoxyprogesterone;6-Methyl-17α-acetoxy-4,6-pregnadiene-3,20-dione;17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;17α-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;6-Methyl-Δ4,6-pregnadien-17α-ol-3,20-dione acetate;Megace;Niagestin;Megestryl acetate;Magestin;Megeron;Ovarid;MGA;Megestin;Nia;Megestat;Maygace;Megestil;Ovaban;NSC 71423;Megalia
CAS No.:595-33-5
Molecular Formula:C24H32O4
InChIKeys:InChIKey=RQZAXGRLVPAYTJ-GQFGMJRRSA-N
Molecular Weight:384.51
Exact Mass:384.51
EC Number:209-864-5
UNII:TJ2M0FR8ES
NSC Number:71423
DSSTox ID:DTXSID9040683
NCI Thesaurus Code:C1156
HScode:29372390
Categories:
Characteristics-
PSA:
60.4
XLogP3:3.2
Appearance:Crystalline Solid
Density:1.2±0.1 g/cm3
Melting Point:214 °C
Boiling Point:431.17°C (rough estimate)
Flash Point:218.5±30.2 °C
Refractive Index:1.551
Water Solubility:2 µg/mL (at 37 °C for the acetate salt)
Storage Conditions:Refrigerator
Toxicity:LD50 intravenous in mouse: 56mg/kg
Specific rotation:D24 +5° (chloroform)
Collision Cross Section:180.1 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Carcinogenicity, Category 2
Specific target organ toxicity â repeated exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H351 Suspected of causing cancer
H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Peptides,Retatrutide,GHK-CU
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Location:
Room 503, 5th Floor, Office Unit 501, New Triumphal Arch Health Products Mall, Changzheng Road, Chengguan Town, Taihe County, Fuyang City, Anhui Province
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Payment Terms:
TT against copy of documents,D/P,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
3
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
51-100
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Year of Establishment:
2026
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Megestrol acetate
15 KG Mar 12, 2024 Post an enquiry for this product
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