Decapeptide-12 Powder CAS 137665-91-9 | Cosmetic Peptide Raw Materials

Decapeptide-12, as a linear peptide chain composed of ten amino acid residues, has attracted extensive attention in basic research fields such as cell signal transduction, dermatobiology and neural regulation because of its unique molecular configuration and potential biological activity.

Chemical structure and nomenclature specification of Decapeptide -12
The standard sequence of Decapeptide-12 is Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-Thr-Gly-NH, which belongs to the derivative structure of opioid peptide family. The sequence started with tyrosine (Tyr) as the N-terminal, and the C-terminal was amidated, which enhanced its stability in vitro.

It is worth noting that D- Alanine, an unnatural amino acid, is significantly different from endogenous peptides, which makes it show unique behavior in receptor binding selectivity.

Decapeptide -12 usually exists in the form of white to white freeze-dried powder at room temperature, and is easily soluble in dilute aceticacid or water solution containing a small amount of organic solvent (such as DMSO). Its molecular weight is about 1200 Da, and the specific value fluctuates slightly due to the difference of batch purity and salt type.

Because it contains easily oxidizable residues such as tryptophan (Trp) and me thionine (Met), the peptide is sensitive to light, heat and oxidation environment. It is suggested to store it in the dark below -20℃ and avoid repeated freezing and thawing.

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