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Betuak Betulin

Name: Betuak Betulin
Brand: Cuicheng Bio
SKU: pr2606011613
Price: 15 USD
Availability: InStock

4 Inquiries

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CAS No.:

473-98-3

Grade:

Industrial Grade

Content:

98%

Port:

guanghzou

Brand:

Cuicheng Bio

Packaging:

g/kg

Price valid (until):

2026-07-03

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
Seller Information
Inquiry History

Description

Betuak® Betulin is a high-purity, branded commercial form of betulin (CAS Number: 473-98-3). It is a natural lupane-type pentacyclic triterpenoid extracted predominantly from the outer bark of the white birch tree (Betula platyphylla).

Betuak® Betulin functions primarily as a multi-target bioactive ingredient in skincare, dietary supplements, and pharmaceutical research:

Key Biological and Pharmacological Functions

Dermatological and Wound Healing Support: It accelerates skin regeneration by stimulating fibroblast activity and promoting extracellular matrix production. It effectively promotes epithelialization (the closing of wounds) while calming localized irritation. [1]
Anti-Inflammatory and Immunomodulatory Activity: It works by down-regulating major pro-inflammatory signaling pathways, including the NF-$\kappa\text{B}$ and MAPK cascades. This inhibits the secretion of chronic inflammatory cytokines like Interleukin-6 (IL-6). [1, 2]
Antitumor and Pro-Apoptotic Effects: It exhibits antineoplastic properties against several malignant profiles, such as melanoma, lung cancer, and breast cancer. It induces cell death (apoptosis and ferroptosis) selectively in abnormal or precancerous lesions (like actinic keratosis) while leaving healthy tissue intact. [1, 2, 3]
Metabolic and Liver-Protective Regulation: It aids in weight and lipid homeostasis by lowering postprandial hyperglycemia via the inhibition of $\alpha $-amylase and $\alpha $-glucosidase. It protects liver cells by preventing systemic lipid peroxidation and oxidative stress. [1, 2]
Antioxidant and Membrane Stabilization: Betulin molecules naturally intercept free fatty acids and embed themselves within cellular membranes, shielding cell walls from breakdown caused by reactive oxygen species (ROS). [1, 2]
Antimicrobial Protection: It provides broad-spectrum bacteriostatic protection by physically disrupting bacterial membranes. This action interferes with the metabolic pathways of pathogens such as E. coli and Staphylococcus aureus. [1]

Industrial and Formulation Functions

Precursor for Betulinic Acid: In pharmaceutical synthesis, it serves as the foundational chemical building block for manufacturing betulinic acid, a compound with even higher potency for anti-HIV and selective anti-melanoma research. [1]
Cosmetic and Hair Care Stabilizer: In high-end cosmetic lines, it is used in shampoos and scalp treatments to curb scalp inflammation, soothe atopic dermatitis, and strengthen hair follicles. [1, 2]

ECHEMI Editorial Reference

Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.
Solid
Betulin is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-hydroxymethyl substituents. It has a role as a metabolite, an antiviral agent, an analgesic, an anti-inflammatory agent and an antineoplastic agent. It is a pentacyclic triterpenoid and a diol. It derives from a hydride of a lupane.

Basic Info

Product Name:

Betulin

Other Name:

Lup-20(29)-ene-3,28-diol,(3β)-;Lup-20(29)-ene-3β,28-diol;Lup-20(30)-ene-3β,28-diol;3aH-Cyclopenta[a]chrysene,lup-20(29)-ene-3,28-diol deriv.;(3β)-Lup-20(29)-ene-3,28-diol;Betuline;Betulin;Betulinol;Trochol;Betulol;3β,28-Dihydroxylup-20(29)-ene;NSC 4644;Betulinic alcohol;(+)-Betulin;3,28-Dihydroxy-lupeol;1406-58-2;1192133-66-6;1417540-43-2;2088830-44-6

CAS No.:

473-98-3

Molecular Formula:

C30H50O2

InChIKeys:

InChIKey=FVWJYYTZTCVBKE-ROUWMTJPSA-N

Molecular Weight:

442.71700

Exact Mass:

442.72

EC Number:

207-475-5

UNII:

6W70HN7X7O

NSC Number:

692218

HScode:

29181985

Categories:

Skin Conditioning

Characteristics

PSA:

40.46000

XLogP3:

6.99720

Appearance:

white crystalline powder

Density:

0.9777 g/cm³ @ Temp: 16 °C

Melting Point:

250 °C

Boiling Point:

157.8 °C @ Press: 12 Torr

Flash Point:

210.9ºC

Refractive Index:

1.5186

Water Solubility:

0.0001726 mg/L @ 25 °C (est)

Storage Conditions:

2-8ºC

Vapor Pressure:

4.32E-13mmHg at 25°C

Collision Cross Section:

208.3 Å² [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Betulin Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Betulin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
Poland	betulin	10 KG	Dec 11, 2023
Sweden	Betulin 95%	1 KG	Jan 23, 2026
Australia	Beuteniol 99%	1 KG	Jun 11, 2026
Austria	Betulin	10 KG	Jun 11, 2024

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Betulin 98%HPLC ,Aktin chemicals, the largest producer of Betulin in China	Pharmaceutical Grade/98		Aktinchem	Inquiry
Betulin, CAS:473-98-3	Reagent Grade/99	$20-24/KG FOB	Guangzhou Yaoguang Technology Co., Ltd.	Inquiry

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Betuak Betulin

Product Description

Seller Information