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Factory Supply Whole Sale and Retail CAS 58725-39-6 N-Dodecanoyl-L-Proline 99%

Name: Factory Supply Whole Sale and Retail CAS 58725-39-6 N-Dodecanoyl-L-Proline 99%
Brand: ONERBIO
SKU: pr2606021231
Price: 10.33 USD
Availability: InStock

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Unit Price:

$10.33-10.5/KG EXW

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CAS No.:

58725-39-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-12-31

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Wuhan Oner Biotech Co.,Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

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Product Description
Seller Information
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Description

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Product Name: N-Dodecanoyl-L-proline
CAS Number: 58725-39-6
Molecular Formula: C₁₇H₃₁NO₃
Molecular Weight: 297.43 g/mol
Appearance: White to off-white crystalline powder.

N-Dodecanoyl-L-proline (CAS 58725-39-6), also known as N-lauroyl-L-proline, is a high-purity, amino acid-derived compound formed through the acylation of L-proline with a dodecanoyl (lauryl) fatty acid chain. This amphiphilic structure combines the hydrophilic properties of an amino acid with the lipophilic characteristics of a long-chain fatty acid, yielding a molecule with useful interfacial and compatibility properties in formulation systems. It serves as a versatile chiral intermediate and building block in organic synthesis, particularly for the design of peptide-based therapeutics and specialty functional derivatives. In cosmetic and personal care development, it is evaluated as a mild, amino acid-based surfactant raw material, offering compatibility and structural stability in ingredient screening. The compound is also utilized in research involving functional surfactants, bio-derived amphiphiles, and analytical reference standards for chromatographic method development and purity verification of fatty acid–amino acid conjugates. Supplied as a white to off-white crystalline powder with high purity specifications, it demonstrates solubility in DMSO, ethanol, and methanol, and is suitable for laboratory, formulation, and industrial research applications requiring reproducible material performance

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ITEMS	STANDARDS		RESULTS
Description	White to almost white powder		White powder
UV absorbance ratio	A250/A260 A280/A260	0.41-0.49 2.03-2.71	0.45 2.14
PH	2.0-4.0		2.68
Loss on drying	≤5.0%		2.64%
Assay (UV)	≥98.0%		99.17%
Transmittance	≥98.5%		99.1%
Heavy metals	≤10ppm		＜10ppm
Purity (HPLC)	≥98.0%		99.6%
Conclusion	It complies to the standard

For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.
Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).
Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).
Heavy Metals: NMT 20 ppm (typically lower for injectable grades).
Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).
Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.

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As a high-purity pharmaceutical intermediate, L-Tyrosine Ethyl Ester Hydrochloride is predominantly utilized in the chemical synthesis of bioactive peptides, dopamine analogs, and melanin precursors. Its excellent solubility profile makes it an ideal chiral building block for asymmetric synthesis and a critical substrate in enzymatic reactions. Available in purity grades of ≥98% (HPLC), it meets stringent requirements for R&D and cGMP manufacturing processes. Reliable supply ensures batch-to-batch consistency for long-term project scalability.

Vidarabine is classified as a potential reproductive hazard and an irritant. Safety Data Sheets (SDS) mandate the following:

Hazard Statements (H360): May damage fertility or the unborn child (Category 1B).
Precautionary Measures: Use fume hoods and wear impermeable gloves (e.g., nitrile), lab coats, and safety goggles. Avoid generating airborne dust.
First Aid: In case of skin contact, wash immediately with copious soap and water. If inhaled, move to fresh air.
Storage: Store in tightly sealed, light-resistant containers at 2°C to 8°C (refrigerated) for long-term stability. Avoid freezing.

While superseded by newer nucleoside analogs (Acyclovir, Ganciclovir) for systemic use due to better bioavailability and lower toxicity, Vidarabine retains niche value. Its primary current application is ophthalmic ointment (3%) . Pharmacokinetically, the raw material has poor oral bioavailability (<10%) and is rapidly deaminated in the gastrointestinal tract, necessitating parenteral or topical administration.

Vidarabine API is a well-characterized, stable crystalline nucleoside analog. While its systemic use has declined, it remains a critical raw material for topical antiviral ophthalmic preparations, particularly where resistance to other agents occurs. Manufacturers must strictly control impurities (especially Ara-Hx) and water content to ensure final drug product efficacy.

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Research & Reference Note

Factory Supply Whole Sale and Retail CAS 58725-39-6 N-Dodecanoyl-L-Proline 99% is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Authoritative sources

Disclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals

Certificates

Basic Info

Product Name:

1-(1-Oxododecyl)-L-proline

Other Name:

L-Proline,1-(1-oxododecyl)-;1-(1-Oxododecyl)-L-proline;N-Lauroyl-L-proline;N-Dodecanoylproline;N-Dodecanoyl-L-proline;(S)-N-Dodecanoylproline;(2S)-1-Dodecanoylpyrrolidine-2-carboxylic acid

CAS No.:

58725-39-6

Molecular Formula:

C17H31NO3

InChIKeys:

InChIKey=AJWFQCNUNFFTHX-HNNXBMFYSA-N

Molecular Weight:

297.43

Exact Mass:

297.43

EC Number:

261-407-9

Categories:

Nutrition Supplements

Characteristics

PSA:

57.6

XLogP3:

3.92080

Density:

1.031 g/cm3

Boiling Point:

465.3ºC at 760 mmHg

Flash Point:

235.2ºC

Refractive Index:

1.492

See More 1-(1-Oxododecyl)-L-proline Properties 

Hazard Identification

Classification of the substance or mixture

Serious eye damage, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H318 Causes serious eye damage
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1-(1-Oxododecyl)-L-proline Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

Location:
Changqing 5th Road, Jianghan District

Payment Terms:
TT against copy of documents

Average lead Time:
5

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2020

Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.
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Factory Supply Whole Sale and Retail CAS 58725-39-6 N-Dodecanoyl-L-Proline 99%

Product Description

Seller Information

History Price