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Sodium Ascorbate High-Purity, Stable Vitamin C Sodium Salt for Pharmaceutical, Nutritional, and Cosmetic Applications

Name: Sodium Ascorbate High-Purity, Stable Vitamin C Sodium Salt for Pharmaceutical, Nutritional, and Cosmetic Applications
Brand: ONERBIO
SKU: pr2606021250
Price: 10.56 USD
Availability: InStock

TDS 5 Inquiries

Unit Price:

$10.56/KG EXW

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CAS No.:

134-03-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-12-31

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Wuhan Oner Biotech Co.,Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

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Product Description
Seller Information
Inquiry History

Description

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Product Name: Sodium Ascorbate
CAS Number: 134-03-2
Molecular Formula: C₆H₇NaO₆
Molecular Weight: 198.11 g/mol
Appearance: White to off-white crystalline powder.

Sodium Ascorbate (CAS 134-03-2) is the highly stable, water-soluble sodium salt of L-ascorbic acid (Vitamin C), offering superior antioxidant activity with a less acidic profile compared to ascorbic acid itself. This white to off-white crystalline powder exhibits excellent solubility in aqueous media, making it the preferred choice for parenteral formulations, oral supplements, food fortification, and cosmetic products where pH sensitivity is a concern. As a potent free-radical scavenger, it effectively protects against oxidative stress, supports collagen biosynthesis, enhances iron absorption, and maintains redox balance in biological systems. Its enhanced stability against oxidation in solution, combined with its gentle, non-irritating nature, renders it suitable for sensitive formulations including infant nutrition, geriatric care, and topical serums. Manufactured under strict quality control to meet USP, EP, and FCC standards, Sodium Ascorbate delivers consistent purity, low heavy-metal content, and reliable batch-to-batch reproducibility for both research and large-scale industrial production. The compound should be stored in a cool, dry, light-protected environment to preserve its integrity and full antioxidant potency.

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ITEMS	STANDARDS		RESULTS
Description	White to almost white powder		White powder
UV absorbance ratio	A250/A260 A280/A260	0.41-0.49 2.03-2.71	0.45 2.14
PH	2.0-4.0		2.68
Loss on drying	≤5.0%		2.64%
Assay (UV)	≥98.0%		99.17%
Transmittance	≥98.5%		99.1%
Heavy metals	≤10ppm		＜10ppm
Purity (HPLC)	≥98.0%		99.6%
Conclusion	It complies to the standard

For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.
Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).
Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).
Heavy Metals: NMT 20 ppm (typically lower for injectable grades).
Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).
Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.

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As a high-purity pharmaceutical intermediate, L-Tyrosine Ethyl Ester Hydrochloride is predominantly utilized in the chemical synthesis of bioactive peptides, dopamine analogs, and melanin precursors. Its excellent solubility profile makes it an ideal chiral building block for asymmetric synthesis and a critical substrate in enzymatic reactions. Available in purity grades of ≥98% (HPLC), it meets stringent requirements for R&D and cGMP manufacturing processes. Reliable supply ensures batch-to-batch consistency for long-term project scalability.

Vidarabine is classified as a potential reproductive hazard and an irritant. Safety Data Sheets (SDS) mandate the following:

Hazard Statements (H360): May damage fertility or the unborn child (Category 1B).
Precautionary Measures: Use fume hoods and wear impermeable gloves (e.g., nitrile), lab coats, and safety goggles. Avoid generating airborne dust.
First Aid: In case of skin contact, wash immediately with copious soap and water. If inhaled, move to fresh air.
Storage: Store in tightly sealed, light-resistant containers at 2°C to 8°C (refrigerated) for long-term stability. Avoid freezing.

While superseded by newer nucleoside analogs (Acyclovir, Ganciclovir) for systemic use due to better bioavailability and lower toxicity, Vidarabine retains niche value. Its primary current application is ophthalmic ointment (3%) . Pharmacokinetically, the raw material has poor oral bioavailability (<10%) and is rapidly deaminated in the gastrointestinal tract, necessitating parenteral or topical administration.

Vidarabine API is a well-characterized, stable crystalline nucleoside analog. While its systemic use has declined, it remains a critical raw material for topical antiviral ophthalmic preparations, particularly where resistance to other agents occurs. Manufacturers must strictly control impurities (especially Ara-Hx) and water content to ensure final drug product efficacy.

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Certificates

Basic Info

Product Name:

Sodium ascorbate

Other Name:

L-Ascorbic acid,sodium salt (1:1);L-Ascorbic acid,monosodium salt;Ascorbic acid,sodium deriv.;Ascorbicin;Ascorbin;Natrascorb;Natri-C;3-Oxo-L-gulofuranolactone sodium;Sodascorbate;Sodium ascorbate;Sodium L-ascorbate;Vitamin C sodium;Cebitate;Cenolate;Monosodium ascorbate;Ascorbic acid sodium salt;L-Ascorbic acid sodium salt;Iskia C;HBL 508;ASK-P 10KR;CK 40;CK 40 (ascorbate);E 301;E 301 (antioxidant);Limcee;Monosodium L-ascorbate;Vitamin C Na salt;Sodium (+)-L-ascorbate;Sodium L-(+)-ascorbate;Vitamin C Na;Sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate;129940-98-3;156683-68-0;884311-57-3;1017795-34-4;1184919-96-7

CAS No.:

134-03-2

Molecular Formula:

C6H8O6.Na

InChIKeys:

InChIKey=WTTKTIBMFBIUSE-RXSVEWSESA-N

Molecular Weight:

198.11

Exact Mass:

198.014038

BRN:

3767246

EC Number:

205-126-1

UNII:

S033EH8359

DSSTox ID:

DTXSID0020105

Color/Form:

Minute crystals|Minute white to yellow crystals

Categories:

Nutrition Supplements

Characteristics

PSA:

110

XLogP3:

-1.53490

Appearance:

white to slightly yellow powder

Density:

1.799 g/cm3

Melting Point:

220 °C

Boiling Point:

235 °C

Flash Point:

238.2ºC

Refractive Index:

105.5 ° (C=10, H2O)

Water Solubility:

H2O: 620 g/L (20 ºC)

Storage Conditions:

Store at RT.

Vapor Pressure:

1.62E-14mmHg at 25°C

Flammability characteristics:

Flammable; burning produces toxic sodium oxide fumes

Specific rotation:

104 º (c=1, H2O 25 ºC)

Odor:

Odorless

PH:

Between 6,5 and 8,0 (10 % aqueous solution)

Air and Water Reactions:

Water soluble. Aqueous solutions are subject to quick air oxidation at pH greater than 6.0.

Reactive Group:

Alcohols and Polyols

Reactivity Profile:

A weak base. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

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Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Sodium ascorbate Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

Location:
Changqing 5th Road, Jianghan District

Payment Terms:
TT against copy of documents

Average lead Time:
5

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2020

Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Sodium ascorbate	25 KG	May 30, 2025
India	Sodium ascorbate	25 MT	Dec 27, 2023
United States	Sodium Ascorbate	2 MT	Sep 23, 2025
United States	sodium ascorbate	10 MT	Aug 13, 2024
India	Sodium Ascorbate	2 MT	Apr 3, 2024

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