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Home > Food Additives > Nutrition Supplements > Hesperidin for Sale > Bioactive Citrus Flavonone for Advanced Nutraceutical Hesperidin Powder
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Bioactive Citrus Flavonone for Advanced Nutraceutical Hesperidin Powder

TDS 8 Inquiries

Unit Price:

$12/KG EXW

Get Latest Price
CAS No.:

520-26-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-12-31

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

  • Product Description

  • Seller Information

  • History Price

  • Inquiry History

  • Description

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    Chemical Name Hesperidin (also known as Hesperetin 7-rutinoside)
    CAS Number 520-26-3
    Molecular Formula C₂₈H₃₄O₁₅
    Molecular Weight 610.56 g/mol
    Physical Form Fine powder
    Color Off-white to light yellow-brown
    Odor Odorless or slight characteristic odor
    Solubility Practically insoluble in water; freely soluble in pyridine and alkaline solutions; sparingly soluble in methanol and hot glacial acetic acid; insoluble in chloroform and ether
    Melting Point 227–233 °C (decomposes)
    Purity (Typical) ≥ 90% – 98% (HPLC, depending on grade)


    Hesperidin is a naturally occurring flavanone glycoside predominantly found in the peel and membranous parts of citrus fruits, particularly oranges, lemons, and grapefruits. Chemically classified as a citrus bioflavonoid, it consists of the aglycone hesperetin linked to the disaccharide rutinose. This compound is widely recognized for its potent antioxidant properties, capable of scavenging free radicals and reducing oxidative stress at the cellular level.

    In physiological applications, hesperidin has been extensively studied for its capacity to support capillary integrity, improve venous tone, and promote healthy microcirculation, making it a key ingredient in formulations for vascular and circulatory health. Additionally, it exhibits anti-inflammatory, anti-allergic, and mild cholesterol-lowering activities. As a dietary supplement ingredient, hesperidin is valued for its synergistic effects when combined with vitamin C, enhancing overall bioavailability and immune support. Its poor aqueous solubility often drives the development of advanced delivery systems or water-soluble derivatives (such as hesperidin methyl chalcone) to broaden its functional applications in nutraceuticals, functional foods, and cosmetic products. Standardized hesperidin extracts are typically assayed by high-performance liquid chromatography (HPLC) to ensure consistent potency and quality.

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    ITEMS

    STANDARDS

    RESULTS

    Description

    White to almost white powder

    White powder

    UV absorbance ratio

    A250/A260

    A280/A260

    0.41-0.49

    2.03-2.71

    0.45

    2.14

    PH

    2.0-4.0

    2.68

    Loss on drying

    5.0%

    2.64%

    Assay (UV)

    98.0%

    99.17%

    Transmittance

    98.5%

    99.1%

    Heavy metals

    10ppm

    10ppm

    Purity (HPLC)

    98.0%

    99.6%

    Conclusion

    It complies to the standard


    For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

    • Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.

    • Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).

    • Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).

    • Heavy Metals: NMT 20 ppm (typically lower for injectable grades).

    • Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).

    • Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.

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    As a high-purity pharmaceutical intermediate, L-Tyrosine Ethyl Ester Hydrochloride is predominantly utilized in the chemical synthesis of bioactive peptides, dopamine analogs, and melanin precursors. Its excellent solubility profile makes it an ideal chiral building block for asymmetric synthesis and a critical substrate in enzymatic reactions. Available in purity grades of ≥98% (HPLC), it meets stringent requirements for R&D and cGMP manufacturing processes. Reliable supply ensures batch-to-batch consistency for long-term project scalability.


    Vidarabine is classified as a potential reproductive hazard and an irritant. Safety Data Sheets (SDS) mandate the following:

    • Hazard Statements (H360): May damage fertility or the unborn child (Category 1B).

    • Precautionary Measures: Use fume hoods and wear impermeable gloves (e.g., nitrile), lab coats, and safety goggles. Avoid generating airborne dust.

    • First Aid: In case of skin contact, wash immediately with copious soap and water. If inhaled, move to fresh air.

    • Storage: Store in tightly sealed, light-resistant containers at 2°C to 8°C (refrigerated) for long-term stability. Avoid freezing.


    While superseded by newer nucleoside analogs (Acyclovir, Ganciclovir) for systemic use due to better bioavailability and lower toxicity, Vidarabine retains niche value. Its primary current application is ophthalmic ointment (3%) . Pharmacokinetically, the raw material has poor oral bioavailability (<10%) and is rapidly deaminated in the gastrointestinal tract, necessitating parenteral or topical administration.


    Vidarabine API is a well-characterized, stable crystalline nucleoside analog. While its systemic use has declined, it remains a critical raw material for topical antiviral ophthalmic preparations, particularly where resistance to other agents occurs. Manufacturers must strictly control impurities (especially Ara-Hx) and water content to ensure final drug product efficacy.

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    Certificates

    Basic Info
    Product Name:

    Hesperidin

    Other Name:

    4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-,(2S)-;Hesperidin;4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-,(S)-;Flavanone,3′,5,7-trihydroxy-4′-methoxy-,7-(6-O-α-L-rhamnosyl-D-glucoside);(2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one;Cirantin;Hesperidoside;Hesperetin 7-rutinoside;Hesperidine;Hesperetin 7-rhamnoglucoside;NSC 44184;(2S)-Hesperidin;Atripliside B;Hesperetin 7-O-rutinoside;Hesperitin 7-O-rutinoside;15512-51-3;16643-24-6;17654-22-7;28283-75-2;30927-97-0;32737-61-4;106904-63-6;960582-50-7;1817614-33-7

    CAS No.:

    520-26-3

    Molecular Formula:

    C28H34O15

    InChIKeys:

    InChIKey=QUQPHWDTPGMPEX-QJBIFVCTSA-N

    Molecular Weight:

    610.56

    Exact Mass:

    610.56

    EC Number:

    208-288-1

    UNII:

    E750O06Y6O

    DSSTox ID:

    DTXSID9044328

    HScode:

    29389090

    Categories:

    Nutrition Supplements

    Characteristics
    PSA:

    234

    XLogP3:

    -1.1

    Appearance:

    light brown Powder

    Density:

    1.3290 (rough estimate)

    Melting Point:

    262 °C

    Boiling Point:

    930.1°C at 760 mmHg

    Flash Point:

    305.5ºC

    Refractive Index:

    1.695

    Water Solubility:

    Insoluble in water. soluble in organic solvents such as DMSO.

    Storage Conditions:

    2-8°C

    Specific rotation:

    -76 º (c=2,pyridine)

    Collision Cross Section:

    227 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

    Location:

    Changqing 5th Road, Jianghan District

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    5

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2020

    Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

  • Weekly Price

    The chart shows the price trend of the product in the past 12 months.

  • Inquiry History
    8 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Hesperidin 520-26-3

    20 MT Jul 24, 2023
    United Kingdom

    Hesperidin

    25 KG Jun 1, 2026
    Egypt

    Hesperidin

    400.00 KG Jan 29, 2026
    Mexico

    Hesperidin

    3 KG Sep 16, 2025
    India

    Hesperedin

    2.00 KG Feb 26, 2025
    Turkey

    Hesperedin

    1 TON Oct 8, 2024
    Brazil

    Hesperidin

    50 MT Nov 22, 2024
    India

    hesperidin

    10  Apr 22, 2024
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