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Home > Cosmetic Ingredient > Tonics > MOTS-c for Sale > MOTS-c (Human) Hot-selling high-quality Peptide Powder
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MOTS-c (Human) Hot-selling high-quality Peptide Powder buy - image1

MOTS-c (Human) Hot-selling high-quality Peptide Powder

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Unit Price: Get Latest Price
CAS No.:

1627580-64-6

Port:

Chinese mainland

Packaging:

10mg*10vials 20mg*10vials 40mg*10vials

Price valid (until):

2026-09-04

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
45 days
Qualification:
Main Products:

Semag lutide,Tirzepatide,Retatrutide,raw material,GHK-CU,TB500(Thymosin B4 AceTate)

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Pls input...

    MOTS-c is a peptide encoded in mitochondrial DNA. It is believed to be involved in skeletal muscle and glucose metabolism. It is upregulated in response to exercise, and is considered an exercise mimetic. MOTS-c binds to casein kinase 2.

    Recently, the positive effects of MOTS-c, one of the mitochondria-derived peptides, on various diseases have been gradually discovered and reported. MOTS-c targets skeletal muscle and can enhance glucose metabolism. Therefore, MOTS-c plays an important role in the regulation of cardiovascular, diabetes, exercise and longevity. It is a new mitochondrial signaling mechanism and plays a role in regulating intracellular and intercellular metabolism. It has been reported that MOTS-c is a kind of exercise-induced mitochondrial coding regulator, and the level of MOTS-c in skeletal muscle and blood of mice decreases with age. Additionally, as an endocrine factor, MOTS-c is likely to exert its effects through cellular entry, which is an ongoing investigation at multiple ends, including its cellular uptake. Understanding the detailed molecular details of MOTS-c is an ongoing endeavor. It was reported that after 30 minutes of treatment, MOTS-c can exert its effects by entering the cells and exerting its effects. There is still a great deal of unclarity as to how MOTS-c enters cells without being degraded and retains its biological activity. A future study of the mechanism by which MOTS-c enters cells will be of great importance in order to determine how it exerts its clinical therapeutic effect. As a potential target for treatment development, MOTS-c is expected to be used in the treatment development of a variety of diseases. Synthetic biology techniques, such as genetic engineering, can greatly improve biological activity and deliver MOTS-c directly to the acting site, thus further expanding the therapeutic application of MOTS-c. However, the subsequent biosafety problem has always been the focus of attention. How to reduce or eliminate the toxicity of genetically engineered bacteria to the body is a key scientific problem to be solved urgently

    ECHEMI Editorial Reference

    MOTS-c is a 16-amino-acid mitochondria-derived peptide encoded by a short open reading frame within the mitochondrial 12S rRNA region. It is associated with the folate-AICAR-AMPK signaling pathway and has been studied for its role in cellular metabolic regulation. As a peptide research and pharmaceutical raw material, MOTS-c is suitable for biochemical research, analytical studies, and pharmaceutical development.


    MOTS-C Synthetic is a single, non-glycosylated polypeptide chain containing 16 amino acids, having a molecular mass of 2174.59 Dalton and a Molecular formula of C10H152N280O22 S2.

    Certificates

    Basic Info
    Product Name:

    MOTS-c

    Other Name:

    MOTS-c;L-Arginine, L-methionyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-α-glutamyl-L-methionylglycyl-L-tyrosyl-L-isoleucyl-L-phenylalanyl-L-tyrosyl-L-prolyl-L-arginyl-L-lysyl-L-leucyl-;MOTS-C acetate;Cosmetic Peptide Mots-C;MOTS-c POWDER;MOTS-c peptide;MOTS-c 5mg/10mg;H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

    CAS No.:

    1627580-64-6

    Molecular Formula:

    C101H152N28O22S2

    InChIKeys:

    WYTHCOXVWRKRAH-JIJBDQHHNA-N

    Molecular Weight:

    2174.62

    Exact Mass:

    2174.1110958

    EC Number:

    200-001-8

    Color/Form:

    Solid lyophilized powder

    Categories:

    Tonics

    Characteristics
    Density:

    1.44±0.1 g/cm3(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    Mitochondrial-derived peptide (MDP), 16-amino-acid peptide

    Status:

    Research compound — Not FDA approved

    Mechanism:

    MOTS-c (mitochondrial ORF of the twelve S rRNA-c) is a 16-amino-acid peptide encoded by the mitochondrial genome (not nuclear DNA). It is a mitochondrial-derived peptide that regulates metabolic homeostasis by activating the AMPK/PGC-1\u03b1 pathway, improving insulin sensitivity, and enhancing exercise capacity. MOTS-c crosses the blood-brain barrier and has been shown to reduce body weight and improve glucose tolerance in preclinical models.

    Activity note:

    MOTS-c does not act via a traditional receptor. It functions as a metabolic regulator, activating AMPK. Functional effects are observed at micromolar concentrations in cell-based assays.

    Source:

    Lee C, et al. Cell Metab. 2015;21(3):443-454. MCE: MOTS-c (CAS 1627580-64-6).DOI

    References
    PubChem:

    PubChem

    Disclaimer:

    MOTS-c is NOT FDA-approved or EMA-approved. It is a research compound only. All data are from preclinical (cell/animal) studies; no human clinical trials have been completed. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Semag lutide,Tirzepatide,Retatrutide,raw material,GHK-CU,TB500(Thymosin B4 AceTate)

    Location:

    Room 1002-C3973, No. 80, Yongtai Modaonan Street, Yongping Subdistrict, Baiyun District, Guangzhou City

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    45 days

    Year of Establishment:

    2026

    Anymang is a US-based trading company dedicated to the global supply and formulation of high-quality cosmetic raw materials, with a core focus on peptide ingredients. Committed to bridging premium suppliers and beauty manufacturers worldwide, we deliver pure, stable, and efficacious peptides—including anti-aging, brightening, and firming peptides—alongside a full spectrum of cosmetic actives and custom formulation solutions. With rigorous quality control and compliance with US safety standards, we ensure consistent batch quality and reliable delivery. Our experienced team provides professional technical support and tailored services to help clients develop competitive skincare and personal care products. Trusted by partners across the globe, Anymang stands as your dependable partner for innovative, high-performance cosmetic raw materials and peptide formulations.

  • Inquiry History
    136 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Mots-C CAS 1627580-64-6

    5 G Apr 26, 2026
    United States

    Bodygrowth Peptides CAS 1627580-64-6 MOTS-c (Human) Acetate peptides powder

    1 G Feb 23, 2026
    United States

    MOTS-c (Human) Acetate peptides powder

    1 G Mar 12, 2026
    Brazil

    MOTS-c 10mg Peptide Raw Material High Purity

    10 PCS Feb 17, 2026
    United States

    Mots-C

    1 KG Sep 12, 2025
    Hongkong, China

    MOTS-C

    1 KG Sep 10, 2026
    United States

    MOTS-C

    10 MG Aug 12, 2026
    United States

    Mots/c

    100 MG Aug 10, 2026
    United States

    Mots-c

    1 MT Aug 2, 2026
    Ecuador

    MOTS-C

    20 MG Jul 30, 2026
    United States

    MOTS-C Acetate 99%

    50 G Jul 12, 2026
    United Arab Emirates

    MOTSc

    50 KG Jun 19, 2026
    United States

    MOTS C

    2 KG Jun 19, 2026
    China

    MOTS-C

    1000  Jun 15, 2026
    Thailand

    MOTS-c

    100 MG Jun 9, 2026
    United States

    Mots-C

    30 MG May 26, 2026
    United States

    MOTS-C

    10 MT May 15, 2026
    United States

    MOTS-c

    10 MG May 7, 2026
    Malaysia

    MOTS-C

    20 PCS May 2, 2026
    South Korea

    MOTS-c

    10 PCS Apr 26, 2026
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