Factory Supply High quality β-Nicotinamide Adenine Dinucleotide NAD+

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Basic Info.

NAD+ (nicotinamide adenine dinucleotide) is an important coenzyme in human cells, primarily responsible for energy metabolism, DNA repair, and activating sirtuins, proteins associated with longevity. Its levels decline rapidly after age 30, making it a key factor in aging and the development of chronic diseases.

Molecular Structure of NAD+

I. Basic Information

Full Name: Nicotinamide Adenine Dinucleotide

CAS Number: 53-84-9

Molecular Formula: C₂₁H₂₇N₇O₁₄P₂

Molecular Weight: 663.43 Da

Forms: Oxidized (NAD+), Reduced (NADH)

Main Function: Longevity protein. Sirtuins are the only activating substrates and essential coenzymes for mitochondrial energy metabolism.

Age-related changes: Decreases by 8% to 10% annually after age 30, and by half between ages 40 and 60, accelerating aging.

II. Mechanism of Action (Three Major Pathways)

Energy Metabolism (ATP Generation)

Essential coenzymes for mitochondrial oxidative phosphorylation, glycolysis, and fatty acid oxidation

Enhances mitochondrial function, increasing cellular energy production

DNA Repair and Anti-aging

Activates PARP (DNA repair enzyme), repairing damage and reducing mutations

Activates Sirtuins (longevity proteins), regulating aging and extending cell lifespan

Antioxidant and Anti-inflammatory

Activates the Nrf2 pathway, increasing SOD and CAT expression, and scavenging ROS

Inhibits NF-κB, reducing pro-inflammatory factors such as TNF-α and IL-6

III. Main Functions ( (Research/Clinical Grade)

Anti-aging and Longevity: Slows down cellular aging, improves skin aging, and extends healthy lifespan.

Metabolic Regulation: Improves insulin sensitivity, lowers blood sugar, reduces visceral fat, and improves fatty liver.

Energy and Physical Performance: Enhances mitochondrial function, improves endurance, relieves fatigue, and restores physical strength.

Neuroprotection: Can cross the blood-brain barrier, has anti-inflammatory and antioxidant effects, improves cognitive function, and slows down neurodegenerative changes.

Cardiovascular Protection: Improves vascular endothelial function, lowers blood pressure, protects the myocardium, and reduces the risk of atherosclerosis.

Immunity and Repair: Enhances immunity, accelerates wound healing, improves inflammation, and maintains intestinal homeostasis.

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------FAQ------

Is tirzepatide available for weight loss?

It's also FDA approved for chronic weight management in adults with or without diabetes. Along with diet and exercise, tirzepatide can lead to significant weight loss — an average of 15% to 20% (34 lbs to 48 lbs). But tirzepatide for weight loss is only recommended for people who meet certain BMI criteria.

How fast do you lose weight on tirzepatide?

How quickly you lose weight depends on factors like lifestyle habits, diet, activity level, age, and other medications you may be taking. However, most people who follow a healthy diet and exercise routine begin reporting some weight loss within a month to two months of starting the medication.

Which payment is available for your company?

Bank Transfer,Paypal or Bitcoins usdt trc usdt erc and so on.  You can choose the way which is convenient for you.

May I get one sample before placing order?

Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.Mutual effort towards each other.

Why should you buy from us not from other suppliers?

1. Powerful R & D team
2. The ability of quantized production from grams to tons;
3. Various kinds of advanced equipment in the laboratory and plant;
4 .Strict QC standard to meet the demand of customers, advanced equipment for analysis and assay;
5. Efficient and safe logistic plans for chemical products transportation;
6 .Excellent after-sale service.
7. Highest quality and good package
8 .ISO certificate