5AM 10AM 50AM Purity 99% - Customizable available 5mg 10mg

5AM-1MQ is high-quality metabolic peptide material with CAS No.42464-96-0, featuring high purity and stable property. It effectively inhibits fat accumulation, accelerates fat decomposition and burning, greatly boosts basal metabolism, regulates body energy circulation and assists body shaping gently. It can also improve physical vitality, widely used and ideal for healthy body management.

Block the consumption of nicotinamide methylation, increase the content of NAD+ in cells (by 20% - 30%), activate longevity proteins Sirtuins and mitochondrial energy supply;
Inhibit lipid synthesis in fat cells, increase basal metabolism and fat β-oxidation, and animal experiments show that it can reduce visceral fat accumulation (without relying on dieting to control appetite and lose fat);
Improve sensitivity, regulate liver sugar and lipid metabolism. Research direction: obesity, metabolic syndrome, sarcopenia research.# AM-1MQ: High-Purity Metabolic Peptide for Laboratory Research ## Overview AM-1MQ (CAS No. 42464-96-0) is a high-quality research-grade metabolic peptide designed exclusively for scientific investigation into cellular energy regulation, lipid metabolism, and metabolic health. Manufactured to strict purity standards, this peptide features exceptional stability and consistent biological activity, making it a reliable tool for preclinical studies focused on obesity, metabolic syndrome, and related disorders. Its mechanism of action centers on modulating key pathways involved in fat metabolism, cellular energy production, and metabolic homeostasis, supporting reproducible results in a wide range of experimental settings. --- ## Core Mechanisms of Action (Preclinical Research) ### 1. Regulation of NAD+ Metabolism and Longevity Pathways AM-1MQ acts by blocking the consumption of nicotinamide methylation, a process that directly impacts cellular NAD+ levels. In laboratory studies, this effect has been shown to increase intracellular NAD+ content by 20–30%, a critical coenzyme involved in hundreds of metabolic reactions, including energy production and DNA repair. Elevated NAD+ levels, in turn, activate longevity proteins known as sirtuins, which play key roles in regulating cellular stress responses, mitochondrial function, and metabolic efficiency. By supporting mitochondrial energy supply, AM-1MQ serves as a valuable reagent for investigating the link between NAD+ biology, aging, and metabolic health. ### 2. Modulation of Lipid Metabolism and Fat Turnover A primary focus of AM-1MQ research is its effects on adipose tissue biology. Preclinical studies demonstrate that the peptide inhibits lipid synthesis in fat cells, while simultaneously increasing basal metabolism and fat β-oxidation—the process by which the body breaks down stored fat for energy. Animal experiments have further shown that AM-1MQ reduces visceral fat accumulation without relying on appetite suppression or dietary restriction, making it a unique tool for studying fat metabolism independent of caloric intake regulation. These properties make it ideal for investigating the molecular mechanisms of obesity and metabolic dysfunction. ### 3. Enhancement of Metabolic Sensitivity and Hepatic Homeostasis AM-1MQ has also been studied for its effects on metabolic sensitivity and liver function. Research indicates that the peptide improves insulin sensitivity and regulates hepatic glucose and lipid metabolism, supporting balanced blood sugar levels and reducing the risk of metabolic dysregulation. These effects are particularly relevant to studies of metabolic syndrome, a cluster of conditions including insulin resistance, dyslipidemia, and visceral obesity, which increases the risk of cardiovascular disease and type 2 diabetes. --- ## Research Applications AM-1MQ is widely utilized in scientific research across multiple disciplines, including endocrinology, molecular biology, and pharmacology. Key applications include: - **Obesity and Adipose Tissue Research**: Investigating the effects of AM-1MQ on fat cell biology, lipid turnover, and visceral fat accumulation in preclinical models. - **Metabolic Syndrome Studies**: Evaluating the peptide’s impact on insulin sensitivity, glucose homeostasis, and hepatic lipid metabolism in animal models of metabolic dysfunction. - **Sarcopenia and Muscle Metabolism Research**: Exploring the peptide’s effects on mitochondrial function, energy production, and muscle health, particularly in the context of age-related muscle loss. - **NAD+ and Sirtuin Pathway Analysis**: Studying the role of AM-1MQ in modulating cellular NAD+ levels, sirtuin activity, and downstream metabolic signaling cascades. - **Preclinical Drug Development**: Assessing AM-1MQ as a potential lead compound for the development of novel therapies targeting metabolic disorders. --- ## Quality Specifications & Manufacturing Standards All batches of AM-1MQ are produced and tested to meet the highest standards for laboratory research use: | Property | Specification | |------------------------|-------------------------------------------------------------------------------| | CAS Number | 42464-96-0 | | Form | White lyophilized powder | | Purity | ≥98% (HPLC-verified; 99% purity available for select batches) | | Solubility | Highly soluble in water and PBS buffer | | Storage (Dry Powder) | -20°C in a dark, airtight container | | Storage (Reconstituted)| 2–8°C refrigeration; avoid repeated freeze-thaw cycles | | Quality Control | HPLC, mass spectrometry (MS), and endotoxin testing included per batch | ### Quality Assurance - **Purity Verification**: High-performance liquid chromatography (HPLC) confirms the peptide’s purity, eliminating contaminants that could interfere with experimental results. - **Identity Confirmation**: Mass spectrometry (MS) verifies the peptide’s molecular weight and structural identity, ensuring alignment with the target sequence. - **Endotoxin Testing**: Each batch undergoes endotoxin testing to ensure compliance with laboratory research standards, reducing the risk of non-specific inflammatory responses in cell-based or in vivo studies. - **Stability Testing**: Accelerated stability studies confirm the peptide’s stability under recommended storage conditions, preserving its biological activity for long-term use. --- ## Packaging, Handling & Storage Guidelines - **Packaging**: AM-1MQ is supplied in sterile, vacuum-sealed vials containing lyophilized powder, clearly labeled with product name, batch number, purity grade, and expiration date. Custom packaging options are available for bulk research orders. - **Handling**: Standard laboratory safety protocols must be followed when handling the peptide, including the use of sterile gloves and work in a clean, controlled environment to prevent contamination. The lyophilized powder should be reconstituted with sterile water or PBS buffer immediately before use, following specific experimental protocols. - **Storage**: - **Dry Powder**: Store at -20°C in a dark, sealed container to protect from light and moisture. Under these conditions, the product has a shelf life of 24 months from the date of manufacture. - **Reconstituted Solution**: After dissolution, store at 2–8°C and use within 7–14 days. Repeated freeze-thaw cycles must be avoided, as these can compromise the peptide’s structure and biological activity. --- ## Conclusion AM-1MQ is a high-purity, research-grade metabolic peptide designed to advance scientific understanding of cellular energy regulation, lipid metabolism, and metabolic health. With verified purity, stable lyophilized formulation, and well-documented mechanisms of action in preclinical research, it serves as a reliable tool for investigating obesity, metabolic syndrome, and related disorders. Manufactured under strict quality control standards, AM-1MQ ensures reproducible results in sensitive experiments, making it a trusted choice for researchers seeking consistent, high-quality reagents for their studies. Designed exclusively for **laboratory research use only**, AM-1MQ is not intended for diagnostic, therapeutic, or human consumption purposes. Backed by comprehensive quality assurance and technical support, it is an essential resource for advancing metabolic research and drug development efforts worldwide. For inquiries about bulk ordering, custom formulations, or additional technical specifications, please contact our sales team through ECHEMI’s official channels.