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TB500 High purity

Name: TB500 High purity
Brand: Suitai
SKU: pr2606051195
Price: 10 USD
Availability: InStock

Unit Price: Get Latest Price 

Grade:

Research Grade

Content:

99%

Port:

Guangzhou

Brand:

Suitai

Packaging:

10mg, 50mg, 100mg, 1g, 5g, 10g per vial or foil bag; Custom packaging available upon request

Price valid (until):

2026-07-05

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STARBEAUTY BIOTECH LIMITED

Company Type:

Trader

Location:

Hongkong, China

Qualification:

Main Products:

peptide,Cosmetics

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Product Description
Seller Information

Description
TB500
Items Specifications

Apperance Powder

Key words H10

Function Weight Loss

1. Product Basic Overview

TB500 is a synthetic bioactive peptide fragment derived from the active domain of composed of the core active amino acid sequence Ac-LKKTETQ, sourced via standardized laboratory chemical synthesis. The parent exists in mammalian somatic cells, platelets and tissue fluid, functioning as a key actin-binding regulatory substance in organisms. Our TB500 is supplied as lyophilized white powder, strictly manufactured as research laboratory raw material only, not for human medication, injection, oral intake or clinical treatment purposes.

Core Specs

Appearance: White sterile lyophilized powder

HPLC Purity: ≥99%

Available Specification: 5mg/10mg per vial

Molecular Formula & Weight: Standard synthetic peptide specification, COA certification attached per batch

Storage Condition: Sealed storage at 2–8℃ under dry, dark environment; reconstituted solution requires refrigerated preservation and short-cycle usage

2. Molecular Research Principle

In published pre-laboratory studies, TB500 mainly regulates intracellular free G-actin protein balance, optimizes cytoskeleton construction and accelerates orderly migration of fibroblasts, epithelial cells and endothelial cells toward damaged tissue areas; meanwhile it modulates partial inflammation-related signaling pathways to ease excessive inflammatory response during tissue remodeling and restrain abnormal fibrocyte hyperplasia which causes excess scar formation. Its unique peptide structure supports in-vitro experimental research focusing on cell mobility, angiogenesis and tissue remodeling mechanisms.

3. Main Research Application Directions

Skin tissue related laboratory research: Widely adopted for in-vitro tests of epidermal micro-damage repair, barrier reconstruction, inflammatory skin model exploration, scar inhibition and microcirculation improvement experiments for cosmetic raw material development.

Musculoskeletal tissue study: Applied in preclinical cell and tissue experiments targeting tendon, ligament and skeletal muscle cell repair, focusing on post-damage tissue remodeling research in lab animal models.

Angiogenesis & anti-inflammation research: Used for lab exploration of new capillary formation, chronic inflammatory cell regulation and anti-fibrosis related basic biological research across multiple organ tissue models.

Biomedical raw material development research: Core test substance for regenerative biological raw material screening, formulation compatibility verification in cosmetic & biomaterial lab development.

4. Product Advantages

✅ High-purity refined production: Adopts strict HPLC purification technology, batch-by-batch test with complete COA quality report, low impurity residue and stable chemical property for repeated lab tests.

✅ Strict sterile lyophilization process: Vacuum freeze-dried under aseptic workshop, effectively avoid peptide activity degradation during shelf storage.

✅ Stable batch consistency: Fixed synthetic production route, uniform molecular activity between different batches to guarantee reproducible experimental data.

✅ Flexible packaging: Multiple specification vial packing to satisfy different lab test dosage demands, fast global warehouse shipment.

5. Important Disclaimer Statement

All descriptions above are summarized based on existing public academic laboratory research literature only. This product is exclusively sold as raw material for scientific laboratory research and in-vitro experiment, prohibited from any human body administration, clinical diagnosis, therapeutic usage or personal non-laboratory application; buyers shall bear full responsibility for compliance with local regional import and usage regulatory rules.
Basic Info

Product Name:
TB500, Tβ4, Cibinetide, Peptide API, Regenerative Medicine, Wound Healing, Anti-inflammatory Peptide, GMP Grade, Research Chemical

Categories:
Polypeptide

Research

Class:
Actin-sequestering protein / 43-amino-acid peptide

Status:
Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)

Mechanism:
A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.

Activity note:
Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.

Source:
Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI

Clinical Development:
NCT02974907; NCT02600429; NCT00376974

References

DrugBank:
DB04951

PubChem:
PubChem

UNII:
549LM7U24W

Literature:
PubMed: Goldstein AL et al. (2003) — Review; ClinicalTrials.gov: ARISE-1 (NCT02974907)

Disclaimer:
Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Seller Information

Business Type:
Trader

Main Products:
peptide,Cosmetics

Location:
FLAT E19, 10/F, NO .52 HUNG TO ROAD, KWUN TONG HONG KONG

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
3

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2026

Introduction to Peptide Manufacturing Factory

Our peptide manufacturing factory is a professional, standardized and intelligent production base dedicated to the research, development and mass production of high-purity custom peptides and standard peptides. Adhering to strict pharmaceutical and biochemical production standards, we integrate independent R&D, precision production, rigorous quality testing and customized technical services, committing to providing high-quality peptide products and reliable solutions for global customers.

Equipped with advanced fully automated peptide synthesis production lines, purification systems and freeze-drying equipment, the factory supports multi-scale production ranging from milligram-level laboratory samples to kilogram-level industrial mass production. We cover mainstream synthesis technologies such as solid-phase peptide synthesis and liquid-phase peptide synthesis, and can efficiently customize various complex peptides, including long-chain peptides, cyclic peptides, modified peptides, fluorescent-labeled peptides and phosphorylated peptides. Our product portfolio widely serves biopharmaceutical research, cosmetic raw material development, food additive production, academic scientific research, diagnostic reagent preparation and other fields.

Quality control is the core of our production management. The factory has built a complete quality management system in line with ISO international standards, with independent professional testing laboratories. We adopt high-performance liquid chromatography (HPLC), mass spectrometry (MS), infrared spectroscopy and other precision testing methods to strictly monitor raw material screening, synthesis reaction, purification treatment, finished product packaging and every production link. This ensures that all peptide products feature high purity, stable properties, accurate molecular weight and low impurity content, meeting the differentiated quality requirements of scientific research experiments and industrial production.

With a professional technical team composed of senior peptide synthesis engineers and biochemical researchers, we have rich experience in solving difficult peptide synthesis problems and optimizing production processes. While guaranteeing product quality and production efficiency, we continuously optimize production processes, reduce production costs and shorten delivery cycles. In addition, we provide one-stop services including peptide design scheme optimization, technical consultation, after-sales technical support and personalized packaging, winning long-term trust and cooperative relationships with customers at home and abroad.

Sticking to the development concept of "technology innovation, quality supremacy, customer-oriented", our factory keeps upgrading production equipment and R&D capabilities, and strives to become a competitive professional peptide manufacturing supplier in the global biochemical industry.
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Items	Specifications
Apperance	Powder
Key words	H10
Function	Weight Loss

TB500 High purity

Product Description

Seller Information

1. Product Basic Overview

Core Specs

2. Molecular Research Principle

3. Main Research Application Directions

4. Product Advantages

5. Important Disclaimer Statement

Related Products