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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Dihexa for Sale > Best Price Nootropics Dihexa CAS NO.1401708-83-5 dihexa Powder hotsales
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Best Price Nootropics Dihexa CAS NO.1401708-83-5 dihexa Powder hotsales

TDS 172 Inquiries

Unit Price:

$11-12/MT FOB

Get Latest Price
CAS No.:

1401708-83-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

zhongshuan

Packaging:

10vials/box

Price valid (until):

2027-03-05

Company Type:
Trader
Location:
China
Average Lead Time:
15 days
Qualification:
Main Products:

peptide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Contact Name : Anne
    whatsapp number :+8618034597101
    Email :18034597101@163.com


    Dihexa is a small peptide composed of eight amino acids, and it is closely associated with cognitive enhancement and potential neurological benefits. It is a derivative of the angiotensin IV, which has been studied for its effects on memory and learning. Researchers have investigated Dihexa for its ability to promote synaptogenesis, the formation of new synapses in the brain, which may help in conditions such as neurodegenerative disorders and cognitive decline.

    Items Specifications
    Product Name

    Dihe xa

    CAS No 1401708-83-5
    Purity ≥99.0%
    Appearance Appearance
    Packaging 5mg 10mg


    Dihexa dramatically improves cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

    Dihexa, with the chemical formula C30H53N11O9, has the CAS number 1401708-83-5. It is a peptide compound that belongs to the class of nootropic drugs. Dihexa appears as a white powder with no distinct odor. Its basic structure consists of a hexapeptide chain attached to a dipeptide chain. This compound is soluble in water. Dihexa is considered to be safe for use in research and experimental purposes. However, its safety for human consumption has not been fully evaluated. It is important to handle Dihexa with caution and follow proper safety protocols when working with this compound.

    Product: Dihexa
    Synonyms:PNB-0408; PNB 0408; PNB0408; Dihexa; N-hexanoic-Tyr-Ile-(6) aminohexanoic amide; N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide
    CAS #: 1401708-83-5
    Molecular Formula: C27H44N4O5
    Molecular Mass: 504.672  (g/mol)
    Amino Acid Sequence: Hexanoyl-Tyr-Ile-Ahx-NH2
    Purity: 99.0%
    Appearance: White Lyophilized Powder
    Minimum Order Quantity: 1g
    Test Method: HPLC
    Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below-18° C. 

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    About us

    Shop Sufficient supply Hot Selling Best Price Dihexa cas1401708-83-5 dihexa Powder-Detailed Image 11 Shop Sufficient supply Hot Selling Best Price Dihexa cas1401708-83-5 dihexa Powder-Detailed Image 12 Shop Sufficient supply Hot Selling Best Price Dihexa cas1401708-83-5 dihexa Powder-Detailed Image 13 Shop Sufficient supply Hot Selling Best Price Dihexa cas1401708-83-5 dihexa Powder-Detailed Image 14

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    FAQ


    Q1: About the after-sale service

    A: After purchasing the products from our Lab, we have A professional technical team and after-sales team to serve you and solve all your problems in the future

    Q2: Do you have stock?

    A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.

    Q3: How do I start paying?

    Payment can be made by Bitcoin,wire transfer or paypal

    Q4: How to confirm product quality before placing an order?

    A: We got good feedback from customers and Tested by third-party institutions. You also can get free samples of some products. You just have to pay the shipping fee for the sample .

    You can send us your product specifications and requirements and we can customize for you.

    Q5: What is your MOQ?

    A: The minimum quantity we can order is 1 box.

    But usually we can accept a smaller quantity, say 100g, at the cost of 100% sample charge.

    Q6: Time for delivery?

    A: Leading time within 3 business days,Shipping time about 8-10 business days.

    Q7: Why should I choose you?

    A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5years, in average.Strict quality control-comes form our sophisticated management system.Professional and warm sales team-since we believe we can only win via our hard work in a competitive world.Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service.


    ECHEMI Editorial Reference

    Dihexa is a synthetic peptide-based compound and angiotensin IV analog. As a research and pharmaceutical raw material, Dihexa is characterized by its defined molecular structure and peptide properties. It is primarily used for research, analytical testing, compound evaluation, and pharmaceutical development.

    Certificates

    Basic Info
    Product Name:

    Dihexa

    Other Name:

    L-Isoleucinamide,N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide;Dihexa;N-Hexanoic-Tyr-Ile-(6)aminohexanoic amide

    CAS No.:

    1401708-83-5

    Molecular Formula:

    C27H44N4O5

    InChIKeys:

    InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N

    Molecular Weight:

    504.7

    Exact Mass:

    504.66

    Characteristics
    Density:

    1.111±0.06 g/cm3(Predicted)

    Boiling Point:

    866.2±65.0 °C(Predicted)

    Research
    Class:

    Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

    Status:

    Research compound — Not FDA approved

    Mechanism:

    A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

    EC50 (HGF Binding KD):

    65 pM

    Activity note:

    Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

    Source:

    Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

    Clinical Development:

    NCT04488419

    References
    PubChem:

    PubChem

    UNII:

    9WYX65A5C2

    Disclaimer:

    Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    peptide

    Location:

    Room A0693, 6th Floor, Building 3, No.5 Lvtai Road, Zhongtai Subdistrict, Yuhang District, Hangzhou City, Zhejiang Province

    Average lead Time:

    15 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    51-100

    Year of Establishment:

    2025

    Company Certificates
    • Hangzhou Zhongshuan Technology Co., Ltd.TR60 COA TR60 COA

    Hangzhou ZhongShuan Technology Co., Ltd. specializes in the R&D and manufacturing of pharmaceutical-grade and healthcare-grade bioactive raw materials and their derivatives, which are widely used in pharmaceuticals, nutraceuticals and cosmetics industries and have gained global recognition for superior bioactivity and safety. Our 100,000-square-meter factory is built in strict compliance with GMP standards, boasting a clean production environment, scientific layout, and complete R&D and manufacturing facilities for deep processing of bioactive raw materials and solvent purification, laying a solid foundation for product quality. We are committed to providing global customers with high-quality products and customized professional solutions, and strive to drive product upgrading across various industries through in-depth cultivation of biotechnology.

    Global Market Reach
    The company's products, with their outstanding quality and stable performance, are exported to over, including the Middle East, South America, North America, Southeast Asia, Africa, Europe, etc., and have accumulated a good reputation in overseas markets. Relying on our professional team and global resource integration capabilities, we fully leverage our geographical and supply chain advantages, continuously optimize localized operations, and effectively help customers reduce costs and improve efficiency while ensuring high-quality products.

    Engaged in Raw Materials for 10+ Years
    We are a biotech enterprise engaged in the R&D, production, and sales of peptides and raw materials for more than 10 years.  The company has complete experimental facilities. Advanced testing instruments ensure the stability of product quality from all aspects. If you're interested in our products, don't hesitate to contact us.

  • Inquiry History
    172 Inquiries
    Country Product Purchase Quantity Date Posted
    Canada

    Dihexa lyophilized 1401708-83-5

    1  Aug 23, 2026
    Canada

    Dihexa 1401708-83-5

    1 G Mar 8, 2026
    Bulgaria

    Customized peptides high purity Dihexa with fast shipping door to door CAS 1401708-83-5

    10 G May 27, 2025
    United States

    Dihexa

    500 G Aug 19, 2026
    United States

    Dihexa

    25 G Jan 26, 2025
    Russia

    DIHEXA

    50.00 G Aug 14, 2024
    United States

    Dihexa

    10 G Sep 9, 2026
    India

    Dihexa

    10 MG Sep 4, 2026
    Norway

    Dihexa

    1 G Aug 26, 2026
    United States

    Dihexa

    1 G Aug 22, 2026
    United States

    Dihexa

    1 G Aug 4, 2026
    United States

    Dihexa

    1 G Jul 30, 2026
    United States

    Dihexa

    1 G Jul 8, 2026
    United States

    Dihexa

    10 MG Jul 6, 2026
    Australia

    Dihexa

    1 G Jun 30, 2026
    United States

    Dihexa Peptide Nootropic Neurotrophy Dihexa Powder (Pharmaceutical Grade)

    1.0 G Jun 5, 2026
    United States

    Dihexa

    1 MT May 9, 2026
    United States

    dihexa

    1 KG May 8, 2026
    Canada

    Dihexa

    3 G May 7, 2026
    United States

    Dihexa

    123456 G May 4, 2026
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