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Lariciresinol dimethyl ether

Name: Lariciresinol dimethyl ether
Brand: Cuicheng Bio
SKU: pr2606081145
Price: 300000 USD
Availability: InStock

Unit Price:

$300000-350000/G FOB

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CAS No.:

67560-68-3

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

5mg

Price valid (until):

2026-07-08

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
Seller Information

Description

Lariciresinol dimethyl ether (also known as dimethyl lariciresinol) is a naturally occurring furanoid lignan compound. As the fully methylated derivative of lariciresinol, it is widely distributed within the volatile essential oils and lipophilic extracts of plants such as bay laurel, black pepper, nutmeg, and certain medicinal species within the Magnoliaceae and Lauraceae families.

Its primary functions span neuroinflammatory suppression, microglial protection, botanical chemical defense, and serving as a chiral template in organic synthesis.

1. Neuroinflammatory Suppression and Brain Protection

Inhibition of Microglial Activation: In neuropharmacological research, this compound demonstrates promising anti-neuroinflammatory activities. It has been shown to significantly suppress the abnormal activation of brain microglia (such as BV-2 cells) induced by lipopolysaccharides (LPS).
Downregulation of Pro-Inflammatory Mediators: Its core mechanism involves blocking specific intracellular signaling cascades to halt the overproduction of nitric oxide (NO), prostaglandin E2 (PGE₂), and key pro-inflammatory cytokines like TNF-α and IL-1β. This property makes it an active molecule of interest for researching preventive therapies against chronic neuroinflammation-driven conditions like Alzheimer's and Parkinson's diseases.

2. Botanical Chemical Defense Matrix

Natural Endogenous Phytoalexin: Within host plants, lariciresinol dimethyl ether functions as a robust secondary defense metabolite. It possesses broad-spectrum antimicrobial and antifungal activities, successfully shielding the plant's heartwood and bark tissues from wood-rotting fungi and opportunistic bacterial pathogens.
Insect Antifeedant and Deterrent: Due to its specific chemical structure and volatile traits, it exhibits clear contact toxicity and antifeedant properties against various agricultural pests and larvae, acting as a natural weapon to deter herbivores from grazing.

3. Antioxidant and Cytoprotective Activity

Mitigating Localized Oxidative Stress: Although the phenolic hydroxyl groups of its parent compound have been fully methylated, the central furanoid ring and benzene framework can still participate in electron-transfer pathways under specific cellular conditions. This allows the molecule to exert a baseline inhibition against lipid peroxidation, scavenging free radicals to help stabilize vulnerable cellular membranes.

4. Synthetic Chemistry and Analytical Reference Utility

Chiral Structural Scaffold: Lariciresinol dimethyl ether features a highly rigid, symmetrical tetrahydrofuran core with multiple continuous chiral centers. Because of its excellent lipophilicity and structural stability, it serves as a valuable chiral building block for medicinal chemists synthesizing more complex polyphenolic or functional lignan derivatives.
- Analytical Quality Reference Standard: High-purity forms are utilized in analytical chemistry as validated standards. Researchers employ it in high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) to map chemical fingerprints, authenticate botanical extracts, and prevent adulteration in commercial essential oils.

Basic Info

Product Name:

Lariciresil dimethyl ether

Other Name:

Lariciresil dimethyl ether;Lariciresinol diMethyl ether

CAS No.:

67560-68-3

Molecular Formula:

C22H28O6

InChIKeys:

AYWPHVUFQNWITL-PNLZDCPESA-N

Molecular Weight:

388.45412

Exact Mass:

388.188599

DSSTox ID:

DTXSID40217892

Categories:

Lignans

Characteristics

PSA:

66.38000

XLogP3:

3.18

Density:

1.2±0.1 g/cm3

Boiling Point:

528.4±50.0 °C at 760 mmHg

Flash Point:

273.4±30.1 °C

Refractive Index:

1.546

See More Lariciresil dimethyl ether Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Lariciresil dimethyl ether Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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Product Name	Grade / Content	Price	Supplier Name	Details
Lariciresinol Dimethyl Ether	Pharmaceutical grad/99	$100/KG EXW	Wuhan Pnq Int Trade Co., Ltd	Inquiry