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Irenolone

Name: Irenolone
Brand: Cuicheng Bio
SKU: pr2606081159
Price: 150000 USD
Availability: InStock

Unit Price:

$150000-180000/G FOB

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CAS No.:

149184-19-0

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

5mg

Price valid (until):

2026-07-08

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
Seller Information

Description

Irenolone (chemically known as 2-hydroxy-4-(4-hydroxyphenyl)phenalen-1-one) is a natural phenylphenalenone-type phytoalexin found primarily in plants of the banana family (Musaceae), such as Musa paradisiaca and Musa itinerans.

Its primary functions include serving as an inducible plant immune defense agent, a potent antifungal molecule, and a valuable chemical marker in metabolomics and fragrance research.

1. Core Biological and Plant Defense Functions (Phytoalexin)

Inducible Immune Defense: Irenolone functions as a classic phytoalexin. It is not heavily accumulated in healthy banana tissues under normal conditions, but its synthesis is rapidly upregulated when the plant experiences fungal infection, mechanical wounding, or exposure to elicitors like methyl jasmonate (MeJA) or certain antibiotics.
Antifungal Activity Against Banana Pathogens: It exhibits clear antifungal and antimicrobial properties. In nature, it serves to suppress the growth and spread of destructive fungal pathogens, including Mycosphaerella fijiensis (the causative agent of Black Sigatoka disease) and Colletotrichum musae (which causes banana anthracnose).

2. Pharmacological and Bioactivity Research

Low Cytotoxicity Screening: In oncological research, irenolone has been screened against various human cancer cell lines, such as human erythroleukemia (K562) and lung carcinoma (A549). Studies show that it displays negligible direct cytotoxicity even at higher concentrations (e.g., 50 μM), making it valuable as a low-toxicity natural scaffold for comparative drug discovery.
Antioxidant Capabilities: Containing multiple phenolic hydroxyl groups, its structure allows it to act as a potential free radical scavenger, helping to mitigate localized oxidative stress in botanical and early-stage cellular models.

3. Commercial and Industrial Applications

Fragrance and Perfumery Ingredient: In fine chemical manufacturing, specific commercial formulations of irenolone (CAS: 149184-19-0) are utilized in the fragrance industry as an aromatic compound to formulate unique scent profiles and fixative notes.
Metabolomic Quality Standard: In phytochemistry and agricultural science, purified irenolone is used as a reference standard in HPLC and LC-MS. Researchers use it to profile disease-resistance traits in banana cultivars, helping to select and breed crops with stronger natural immunity.

Basic Info

Product Name:

Irenolone

Other Name:

1H-Phenalen-1-one,2-hydroxy-4-(4-hydroxyphenyl)-;2-Hydroxy-4-(4-hydroxyphenyl)-1H-phenalen-1-one;Irenolone

CAS No.:

149184-19-0

Molecular Formula:

C19H12O3

InChIKeys:

InChIKey=UQMKPTIDKHEGFW-UHFFFAOYSA-N

Molecular Weight:

288.29678

Exact Mass:

288.30

Categories:

Phenols

Characteristics

PSA:

57.5

XLogP3:

4.3

Density:

1.433±0.06 g/cm3(Predicted)

Melting Point:

285 °C

Boiling Point:

573.7±50.0 °C(Predicted)

Water Solubility:

2.482 mg/L @ 25 °C (est)

See More Irenolone Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Irenolone Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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Irenolone

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities